An evaluation of numerical integration algorithms for the estimation of the area under the curve (AUC) in pharmacokinetic studies

Six numerical integration algorithms based on linear and log trapezoidal methods as well as four cubic-spline methods were proposed for estimation of area under the curve (AUC). These six different algorithms were implemented using IMSL/IDL command language and evaluated using data simulated under f...

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Bibliographic Details

Published in:	Biopharmaceutics & drug disposition Vol. 16; no. 1; p. 37
Main Authors:	Yu, Z, Tse, F L
Format:	Journal Article
Language:	English
Published:	England 01.01.1995
Subjects:	Algorithms Biological Availability Models, Theoretical Pharmacokinetics Quality Control
ISSN:	0142-2782
Online Access:	Get more information
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