The role of vascular smooth muscle cell apoptosis and migration during uterine spiral artery remodeling in normal human pregnancy

During human uterine spiral artery (SpA) remodeling, vascular smooth muscle cells (VSMCs) are lost and replaced by fibrinoid, incorporating extravillous trophoblast (EVT) cells. The aim of the current study was to determine the relative contributions of apoptosis and migration to VSMC loss during Sp...

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Vydané v:	The FASEB journal Ročník 26; číslo 7; s. 2975
Hlavní autori:	Bulmer, Judith N, Innes, Barbara A, Levey, Joanne, Robson, Stephen C, Lash, Gendie E
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.07.2012
Predmet:	Angiopoietin-2 - pharmacology Apoptosis - physiology Calmodulin-Binding Proteins - metabolism Caspase 3 - metabolism Cell Line Cell Movement - drug effects Cell Movement - physiology Female Humans Immunohistochemistry Lamins - metabolism Matrix Metalloproteinases - metabolism Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - physiology Myocytes, Smooth Muscle - cytology Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - physiology Pregnancy Transforming Growth Factor beta1 - pharmacology Trophoblasts - cytology Trophoblasts - physiology Urokinase-Type Plasminogen Activator - metabolism Uterine Artery - cytology Uterine Artery - physiology Vascular Endothelial Growth Factor A - pharmacology Vascular Endothelial Growth Factor C - pharmacology
ISSN:	1530-6860, 1530-6860
On-line prístup:	Zistit podrobnosti o prístupe
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