Association between cholelithiasis and sialolithiasis: Two longitudinal follow-up studies

This study aimed to evaluate the association between cholelithiasis and sialolithiasis using a national sample cohort in Korea.The Korean National Health Insurance Service-National Sample Cohort (patients ≥20 years old) was collected from 2002 to 2013. In study I, we extracted cholelithiasis patient...

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Published in:Medicine (Baltimore) Vol. 98; no. 25; p. e16153
Main Authors: Kim, So Young, Kim, Hyung-Jong, Lim, Hyun, Lim, Man Sup, Kim, Miyoung, Park, Il-Seok, Choi, Hyo Geun
Format: Journal Article
Language:English
Published: United States the Author(s). Published by Wolters Kluwer Health, Inc 01.06.2019
Wolters Kluwer Health
Subjects:
Adult
Aged
Aged, 80 and over
Case-Control Studies
Cholelithiasis - epidemiology
Cholelithiasis - physiopathology
Cohort Studies
Female
Follow-Up Studies
Humans
Longitudinal Studies
Male
Middle Aged
Observational Study
Proportional Hazards Models
Republic of Korea - epidemiology
Salivary Gland Calculi - epidemiology
Salivary Gland Calculi - physiopathology
Republic of Korea
ISSN:0025-7974, 1536-5964, 1536-5964
Online Access:Get full text
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Summary:This study aimed to evaluate the association between cholelithiasis and sialolithiasis using a national sample cohort in Korea.The Korean National Health Insurance Service-National Sample Cohort (patients ≥20 years old) was collected from 2002 to 2013. In study I, we extracted cholelithiasis patients (n = 21,170) and 1:4 matched control I subjects (n = 84,680) and analyzed the occurrence of sialolithiasis. In study II, we extracted sialolithiasis patients (n = 761) and 1:4 matched control II subjects (n = 3044) and analyzed the occurrence of cholelithiasis. Hazard ratios (HRs) were determined using the stratified Cox proportional hazard model.The HR for sialolithiasis was 1.49 (95% CI = 0.88-2.52) in the cholelithiasis group (P = .14), and the HR for cholelithiasis was 1.18 (95% CI = 0.53-2.59) in the sialolithiasis group (P = .69).We did not find an association between cholelithiasis and sialolithiasis.
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ISSN:0025-7974
1536-5964
1536-5964
DOI:10.1097/MD.0000000000016153