Integrated Skin Transcriptomics and Serum Multiplex Assays Reveal Novel Mechanisms of Wound Healing in Diabetic Foot Ulcers

Nonhealing diabetic foot ulcers (DFUs) are characterized by low-grade chronic inflammation, both locally and systemically. We prospectively followed a group of patients who either healed or developed nonhealing chronic DFUs. Serum and forearm skin analysis, both at the protein expression and the tra...

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Bibliographic Details
Published in:	Diabetes (New York, N.Y.) Vol. 69; no. 10; p. 2157
Main Authors:	Theocharidis, Georgios, Baltzis, Dimitrios, Roustit, Matthieu, Tellechea, Ana, Dangwal, Seema, Khetani, Radhika S, Shu, Bin, Zhao, Wanni, Fu, Jianfang, Bhasin, Swati, Kafanas, Antonios, Hui, Daniel, Sui, Shannan Ho, Patsopoulos, Nikolaos A, Bhasin, Manoj, Veves, Aristidis
Format:	Journal Article
Language:	English
Published:	United States 01.10.2020
Subjects:	Adult Aged Aged, 80 and over Cell Movement - genetics Cell Movement - physiology Cytochrome P-450 CYP1A1 - genetics Cytochrome P-450 CYP1A1 - metabolism Diabetic Foot - metabolism Diabetic Foot - pathology Humans Middle Aged Organic Anion Transporters - genetics Organic Anion Transporters - metabolism Sequence Analysis, RNA Skin - metabolism Skin - pathology Transcriptome - genetics Transcriptome - physiology Vascular Endothelial Growth Factor A - metabolism Wound Healing - genetics Wound Healing - physiology Young Adult
ISSN:	1939-327X, 1939-327X
Online Access:	Get more information
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