Exploring the role of phage plasmids in gene transfers

Bacteriophages and plasmids drive horizontal gene transfer (HGT) in bacteria. Phage-plasmids (P-Ps) are hybrids of plasmid and phages. Pfeifer and Rocha recently demonstrated that P-Ps can serve as intermediates in gene exchanges between these two types of elements, identified categories of preferen...

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Veröffentlicht in:Trends in genetics Jg. 40; H. 7; S. 555 - 557
Hauptverfasser: Szczepankowska, Agnieszka K., Łobocka, Małgorzata
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England Elsevier Ltd 01.07.2024
Schlagworte:
antibiotic resistance genes
Bacteria - genetics
Bacteria - virology
Bacteriophages - genetics
Gene Transfer, Horizontal - genetics
horizontal gene transfer
mobile genetic elements
phage-plasmids
Plasmids - genetics
recombination events
virulence factors
mobile genetic elements
recombination events
antibiotic resistance genes
horizontal gene transfer
phage-plasmids
virulence factors
ISSN:0168-9525
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Zusammenfassung:Bacteriophages and plasmids drive horizontal gene transfer (HGT) in bacteria. Phage-plasmids (P-Ps) are hybrids of plasmid and phages. Pfeifer and Rocha recently demonstrated that P-Ps can serve as intermediates in gene exchanges between these two types of elements, identified categories of preferentially transferred genes, and reconstructed gene flows involving phage P1-like P-Ps. Bacteriophages and plasmids drive horizontal gene transfer (HGT) in bacteria. Phage-plasmids (P-Ps) are hybrids of plasmid and phages. Pfeifer and Rocha recently demonstrated that P-Ps can serve as intermediates in gene exchanges between these two types of elements, identified categories of preferentially transferred genes, and reconstructed gene flows involving phage P1-like P-Ps.
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ISSN:0168-9525
DOI:10.1016/j.tig.2024.04.011