Next-generation sequencing reveals high concordance of recurrent somatic alterations between primary tumor and metastases from patients with non-small-cell lung cancer

Characterization of the genomic changes that drive an individual patient's disease is critical in management of many cancers. In patients with non-small-cell lung cancer (NSCLC), obtaining tumor samples of sufficient size for genomic profiling on recurrence is often challenging. We undertook th...

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Bibliographic Details
Published in:	Journal of clinical oncology Vol. 31; no. 17; p. 2167
Main Authors:	Vignot, Stéphane, Frampton, Garrett M, Soria, Jean-Charles, Yelensky, Roman, Commo, Frédéric, Brambilla, Christian, Palmer, Gary, Moro-Sibilot, Denis, Ross, Jeffrey S, Cronin, Maureen T, André, Fabrice, Stephens, Philip J, Lazar, Vladimir, Miller, Vincent A, Brambilla, Elisabeth
Format:	Journal Article
Language:	English
Published:	United States 10.06.2013
Subjects:	Adult Aged Aged, 80 and over Base Sequence Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - pathology DNA Copy Number Variations DNA, Neoplasm - genetics Female Humans Lung Neoplasms - genetics Lung Neoplasms - pathology Male Middle Aged Mutation Neoplasm Metastasis
ISSN:	1527-7755, 1527-7755
Online Access:	Get more information
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