Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers

To examine the associations between postmortem Alzheimer disease (AD) neuropathology and autopsy-verified cardiovascular disease. The authors examined 99 subjects (mean age at death = 87.6; SD = 8.7) from the Mount Sinai School of Medicine Department of Psychiatry Brain Bank who were devoid of cereb...

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Bibliographic Details
Published in:	Neurology Vol. 66; no. 9; p. 1399
Main Authors:	Beeri, M S, Rapp, M, Silverman, J M, Schmeidler, J, Grossman, H T, Fallon, J T, Purohit, D P, Perl, D P, Siddiqui, A, Lesser, G, Rosendorff, C, Haroutunian, V
Format:	Journal Article
Language:	English
Published:	United States 09.05.2006
Subjects:	Aged, 80 and over Alleles Alzheimer Disease - complications Alzheimer Disease - genetics Alzheimer Disease - pathology Aortic Diseases - complications Aortic Diseases - genetics Apolipoprotein E4 Apolipoproteins E - genetics Atherosclerosis - complications Atherosclerosis - genetics Brain - pathology Cardiomegaly - complications Cardiomegaly - genetics Cardiomegaly - pathology Comorbidity Coronary Disease - complications Coronary Disease - genetics Female Genetic Predisposition to Disease Genotype Heart Ventricles - pathology Humans Male Neurofibrillary Tangles Organ Size Plaque, Amyloid Severity of Illness Index
ISSN:	1526-632X, 1526-632X
Online Access:	Get more information
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