SPULTRA: Low-Dose CT Image Reconstruction With Joint Statistical and Learned Image Models

Low-dose CT image reconstruction has been a popular research topic in recent years. A typical reconstruction method based on post-log measurements is called penalized weighted-least squares (PWLS). Due to the underlying limitations of the post-log statistical model, the PWLS reconstruction quality i...

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Bibliographic Details
Published in:IEEE transactions on medical imaging Vol. 39; no. 3; pp. 729 - 741
Main Authors: Ye, Siqi, Ravishankar, Saiprasad, Long, Yong, Fessler, Jeffrey A.
Format: Journal Article
Language:English
Published: United States IEEE 01.03.2020
The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
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ISSN:0278-0062, 1558-254X, 1558-254X
Online Access:Get full text
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Summary:Low-dose CT image reconstruction has been a popular research topic in recent years. A typical reconstruction method based on post-log measurements is called penalized weighted-least squares (PWLS). Due to the underlying limitations of the post-log statistical model, the PWLS reconstruction quality is often degraded in low-dose scans. This paper investigates a shifted-Poisson (SP) model based likelihood function that uses the pre-log raw measurements that better represents the measurement statistics, together with a data-driven regularizer exploiting a Union of Learned TRAnsforms (SPULTRA). Both the SP induced data-fidelity term and the regularizer in the proposed framework are nonconvex. The proposed SPULTRA algorithm uses quadratic surrogate functions for the SP induced data-fidelity term. Each iteration involves a quadratic subproblem for updating the image, and a sparse coding and clustering subproblem that has a closed-form solution. The SPULTRA algorithm has a similar computational cost per iteration as its recent counterpart PWLS-ULTRA that uses post-log measurements, and it provides better image reconstruction quality than PWLS-ULTRA, especially in low-dose scans.
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ISSN:0278-0062
1558-254X
1558-254X
DOI:10.1109/TMI.2019.2934933