Development of a reliable automated screening system to identify small molecules and biologics that promote human β-cell regeneration

Numerous compounds stimulate rodent β-cell proliferation; however, translating these findings to human β-cells remains a challenge. To examine human β-cell proliferation in response to such compounds, we developed a medium-throughput in vitro method of quantifying adult human β-cell proliferation ma...

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Bibliographic Details
Published in:American journal of physiology: endocrinology and metabolism Vol. 311; no. 5; p. E859
Main Authors: Aamodt, Kristie I, Aramandla, Radhika, Brown, Judy J, Fiaschi-Taesch, Nathalie, Wang, Peng, Stewart, Andrew F, Brissova, Marcela, Powers, Alvin C
Format: Journal Article
Language:English
Published: United States 01.11.2016
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ISSN:1522-1555, 1522-1555
Online Access:Get more information
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