Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 1: normal and chronic wounds: biology, causes, and approaches to care

This is the first installment of 2 articles that discuss the biology and pathophysiology of wound healing, review the role that growth factors play in this process, and describe current ways of growth factor delivery into the wound bed. Part 1 discusses the latest advances in clinicians' unders...

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Vydané v:Advances in skin & wound care Ročník 25; číslo 7; s. 304
Hlavní autori: Demidova-Rice, Tatiana N, Hamblin, Michael R, Herman, Ira M
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States 01.07.2012
Predmet:
Anti-Infective Agents - therapeutic use
Biofilms - growth & development
Chronic Disease
Debridement - methods
Humans
Intercellular Signaling Peptides and Proteins - genetics
Intercellular Signaling Peptides and Proteins - metabolism
Intercellular Signaling Peptides and Proteins - therapeutic use
Keratinocytes - metabolism
Wound Healing - physiology
Wounds and Injuries - classification
Wounds and Injuries - physiopathology
Wounds and Injuries - therapy
ISSN:1538-8654, 1538-8654
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Shrnutí:This is the first installment of 2 articles that discuss the biology and pathophysiology of wound healing, review the role that growth factors play in this process, and describe current ways of growth factor delivery into the wound bed. Part 1 discusses the latest advances in clinicians' understanding of the control points that regulate wound healing. Importantly, biological similarities and differences between acute and chronic wounds are considered, including the signaling pathways that initiate cellular and tissue responses after injury, which may be impeded during chronic wound healing.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1538-8654
1538-8654
DOI:10.1097/01.ASW.0000416006.55218.d0