Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2

Severe pneumonia may evoke acute lung injury, and sphingosine-1-phosphate is involved in the regulation of vascular permeability and immune responses. However, the role of sphingosine-1-phosphate and the sphingosine-1-phosphate producing sphingosine kinase 1 in pneumonia remains elusive. We examined...

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Bibliographic Details

Published in:	Critical care medicine Vol. 46; no. 3; p. e258
Main Authors:	Gutbier, Birgitt, Schönrock, Stefanie M, Ehrler, Carolin, Haberberger, Rainer, Dietert, Kristina, Gruber, Achim D, Kummer, Wolfgang, Michalick, Laura, Kuebler, Wolfgang M, Hocke, Andreas C, Szymanski, Kolja, Letsiou, Eleftheria, Lüth, Anja, Schumacher, Fabian, Kleuser, Burkhard, Mitchell, Timothy J, Bertrams, Wilhelm, Schmeck, Bernd, Treue, Denise, Klauschen, Frederick, Bauer, Torsten T, Tönnies, Mario, Weissmann, Norbert, Hippenstiel, Stefan, Suttorp, Norbert, Witzenrath, Martin
Format:	Journal Article
Language:	English
Published:	United States 01.03.2018
ISSN:	1530-0293, 1530-0293
Online Access:	Get more information
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