The device-aided intrajejunal delivery of levodopa–entacapone–carbidopa intestinal gel the treatment of Parkinson’s disease: overview of efficacy and safety

Device-aided therapies (DATs) have been developed to provide continuous drug delivery (CDD) to people with advanced Parkinson's disease (PD) whose symptoms can no longer be effectively managed with oral or transdermal therapy. Intrajejunal infusion of levodopa-carbidopa intestinal gel (LCIG), d...

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Bibliographic Details
Published in:	Expert review of medical devices Vol. 22; no. 6; pp. 533 - 544
Main Authors:	Popławska-Domaszewicz, Karolina, Metta, Vinod, Odin, Per, Chaudhuri, K Ray
Format:	Journal Article
Language:	English
Published:	England 03.06.2025
Subjects:	Antiparkinson Agents - administration & dosage Antiparkinson Agents - therapeutic use Carbidopa - administration & dosage Carbidopa - adverse effects Carbidopa - therapeutic use Catechols - administration & dosage Catechols - adverse effects Catechols - therapeutic use Clinical Medicine Drug Combinations Drug Delivery Systems - instrumentation Gels Humans Jejunum Klinisk medicin Levodopa - administration & dosage Levodopa - adverse effects Levodopa - therapeutic use Medical and Health Sciences Medicin och hälsovetenskap Neurologi Neurology Nitriles - administration & dosage Nitriles - adverse effects Nitriles - therapeutic use Parkinson Disease - drug therapy Treatment Outcome advanced parkinson’s disease infusion pump Device-aided therapy LECIGON medical device levodopa–carbidopa–entacapone
ISSN:	1743-4440, 1745-2422, 1745-2422
Online Access:	Get full text
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