Silencing of FTS increases radiosensitivity by blocking radiation-induced Notch1 activation and spheroid formation in cervical cancer cells

Increasing evidence(s) suggests that cancer stem cells (CSC) in tumours contribute to radio-resistance and recurrence. Notch plays an important role in the maintenance of CSC in many cancers including cervical cancer. Previously, we have reported the role of Fused Toes Homolog (FTS) in conferring ra...

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Veröffentlicht in:	International journal of biological macromolecules Jg. 126; S. 1318 - 1325
Hauptverfasser:	Prabakaran, D.S., Muthusami, Sridhar, Sivaraman, T., Yu, Jae-Ran, Park, Woo-Yoon
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier B.V 01.04.2019
Schlagworte:	Cancer stem cells Cervical cancer Fused Toes Homolog humans irradiation neoplasm cells Notch precipitin tests Radiation radiation resistance stem cells uterine cervical neoplasms Fused Toes Homolog Cancer stem cells Cervical cancer Notch Radiation
ISSN:	0141-8130, 1879-0003, 1879-0003
Online-Zugang:	Volltext
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