Macroporous scaffold surface modified with biological macromolecules and piroxicam-loaded gelatin nanofibers toward meniscus cartilage repair

Meniscus cartilage has poor self-healing capacity in the inner zone and its damage leads to articular cartilage degeneration. Here we have developed hybrid constructs using polycaprolactone (PCL) and polyurethane (PU) surface modified by gelatin (G), chitosan (C), and hyaluronic acid (H) biomacromol...

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Vydáno v:	International journal of biological macromolecules Ročník 183; s. 1327 - 1345
Hlavní autoři:	Abpeikar, Zahra, Javdani, Moosa, Mirzaei, Seyed Abbas, Alizadeh, Akram, Moradi, Lida, Soleimannejad, Mostafa, Bonakdar, Shahin, Asadpour, Shiva
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Netherlands Elsevier B.V 31.07.2021
Témata:	Animals Biological macromolecules cartilage Cartilage, Articular - surgery cell movement chitosan chondrocytes crosslinking Fourier transform infrared spectroscopy gelatin Gelatin - chemistry gene expression humans hyaluronic acid Meniscus Meniscus - surgery modulus of elasticity nanofibers Nanofibers - chemistry Piroxicam - chemistry Polyesters - chemistry polyurethanes porous media Rabbits Scaffold fabrication Tissue Engineering - methods Tissue Scaffolds - chemistry viability assays Biological macromolecules Scaffold fabrication Meniscus
ISSN:	0141-8130, 1879-0003, 1879-0003
On-line přístup:	Získat plný text
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