Robust Detection and Segmentation for Diagnosis of Vertebral Diseases Using Routine MR Images

The diagnosis of certain spine pathologies, such as scoliosis, spondylolisthesis and vertebral fractures, is part of the daily clinical routine. Very frequently, magnetic resonance image data are used to diagnose these kinds of pathologies in order to avoid exposing patients to harmful radiation, li...

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Bibliographic Details
Published in:Computer graphics forum Vol. 33; no. 6; pp. 190 - 204
Main Authors: Zukić, Dženan, Vlasák, Aleš, Egger, Jan, Hořínek, Daniel, Nimsky, Christopher, Kolb, Andreas
Format: Journal Article
Language:English
Published: Oxford Blackwell Publishing Ltd 01.09.2014
Subjects:
Analysis
Computer graphics
detection
diagnosis
efficient
I.4.6 [Image processing and computer vision]: Segmentation Pixel classification
Image processing systems
inflation
Medical diagnosis
Medical imaging
MRI
Pathology
Scoliosis
segmentation
Spine
Studies
vertebra
Vertebrae
ISSN:0167-7055, 1467-8659
Online Access:Get full text
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Summary:The diagnosis of certain spine pathologies, such as scoliosis, spondylolisthesis and vertebral fractures, is part of the daily clinical routine. Very frequently, magnetic resonance image data are used to diagnose these kinds of pathologies in order to avoid exposing patients to harmful radiation, like X‐ray. We present a method which detects and segments all acquired vertebral bodies, with minimal user intervention. This allows an automatic diagnosis to detect scoliosis, spondylolisthesis and crushed vertebrae. Our approach consists of three major steps. First, vertebral centres are detected using a Viola–Jones like method, and then the vertebrae are segmented in a parallel manner, and finally, geometric diagnostic features are deduced in order to diagnose the three diseases. Our method was evaluated on 26 lumbar datasets containing 234 reference vertebrae. Vertebra detection has 7.1% false negatives and 1.3% false positives. The average Dice coefficient to manual reference is 79.3% and mean distance error is 1.76 mm. No severe case of the three illnesses was missed, and false alarms occurred rarely—0% for scoliosis, 3.9% for spondylolisthesis and 2.6% for vertebral fractures. The main advantages of our method are high speed, robust handling of a large variety of routine clinical images, and simple and minimal user interaction. The diagnosis of certain spine pathologies, such as scoliosis, spondylolisthesis and vertebral fractures, are part of the daily clinical routine. Very frequently, MRI data are used to diagnose these kinds of pathologies in order to avoid exposing patients to harmful radiation, like X‐ray. We present a method which detects and segments all acquired vertebral bodies, with minimal user intervention. This allows an automatic diagnosis to detect scoliosis, spondylolisthesis and crushed vertebrae.
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ISSN:0167-7055
1467-8659
DOI:10.1111/cgf.12343