Structural characterization and anticancer properties of a novel mushroom-derived rhamnogalactan in a triple-negative breast cancer model

Mushroom-derived polysaccharides are known for their diverse biological activities, including immunomodulatory and anticancer properties. Breast cancer, the leading cause of cancer-related death among women worldwide, lacks targeted molecular therapies, underscoring the need for novel therapeutic ag...

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Veröffentlicht in:	Carbohydrate polymers Jg. 364; S. 123735
Hauptverfasser:	de Lara, Eliane Leal, Zavadinack, Matheus, da Silva Milhorini, Shayane, Wurzer, Karin Maciel, Klassen, Giseli, Cordeiro, Lucimara M.C., Iacomini, Marcello
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Elsevier Ltd 15.09.2025
Schlagworte:	additive effect Agaricales - chemistry Anticancer effect Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology breast neoplasms Cell Line, Tumor Cell Proliferation - drug effects Cell Survival - drug effects cell viability death drug therapy drugs Female Galactans - chemistry Galactans - isolation & purification Galactans - pharmacology galactose Heteropolysaccharides Humans Lactarius Lactarius quieticolor molecular weight mushrooms paclitaxel Paclitaxel - pharmacology polysaccharides Rhamnogalactan rhamnose Triple Negative Breast Neoplasms - drug therapy Triple Negative Breast Neoplasms - pathology Triple-negative breast cancer Heteropolysaccharides Anticancer effect Lactarius quieticolor Rhamnogalactan Triple-negative breast cancer
ISSN:	0144-8617, 1879-1344, 1879-1344
Online-Zugang:	Volltext
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