Involvement of human monogenic cardiomyopathy genes in experimental polygenic cardiac hypertrophy

Hypertrophic cardiomyopathy thickens heart muscles, reducing functionality and increasing risk of cardiac disease and morbidity. Genetic factors are involved, but their contribution is poorly understood. We used the hypertrophic heart rat (HHR), a unique normotensive polygenic model of cardiac hyper...

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Bibliographic Details
Published in:	Physiological genomics Vol. 50; no. 9; p. 680
Main Authors:	Prestes, P R, Marques, F Z, Lopez-Campos, G, Lewandowski, P, Delbridge, L M D, Charchar, F J, Harrap, S B
Format:	Journal Article
Language:	English
Published:	United States 01.09.2018
Subjects:	Animals Binding Sites Cardiomegaly - genetics Cardiomyopathies - genetics Gene Expression Profiling Gene Expression Regulation Genome-Wide Association Study Humans Multifactorial Inheritance - genetics Myocardium - metabolism Myocardium - pathology Polymorphism, Single Nucleotide - genetics Rats RNA, Messenger - genetics RNA, Messenger - metabolism Sequence Analysis, DNA microRNA cardiac hypertrophy cardiomyopathy gene expression DNA sequencing
ISSN:	1531-2267, 1531-2267
Online Access:	Get more information
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