Sex cord-like elements in Müllerian lesions: Report of two rare cases and review of the literature

Sex cord-like elements (SCLEs) are uncommon in non-ovarian sex cord lesions in the female genital tract and are most commonly observed in uterine endometrial stromal tumors (EST) and uterine tumors resembling ovarian sex cord tumors (UTROSCT). Here, we describe two rare cases harboring SCLEs. The fi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Human Pathology Reports Ročník 42; s. 300799
Hlavní autoři: Yildiz, Bahadir, Zhang, Huina, McDowell, Jamie Linn, Katerji, Hani, Varghese, Sharlin, Wang, Xi
Médium: Journal Article
Jazyk:angličtina
Vydáno: Elsevier Inc 01.11.2025
Témata:
Adenosarcoma
Endometrial polyp
Pathology
Sex cord-like elements
Adenosarcoma
Sex cord-like elements
Endometrial polyp
ISSN:2772-736X, 2772-736X
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Sex cord-like elements (SCLEs) are uncommon in non-ovarian sex cord lesions in the female genital tract and are most commonly observed in uterine endometrial stromal tumors (EST) and uterine tumors resembling ovarian sex cord tumors (UTROSCT). Here, we describe two rare cases harboring SCLEs. The first case was a 72-year-old female with postmenopausal bleeding. Endometrial curettage showed endometrial polyps with SCLEs, confirmed by immunohistochemical staining for calretinin, Melan A, and inhibin. The second case was a 71-year-old female with a complex cystic and solid mass in the left ovary, and bilateral salpingo-oophorectomy revealed an ovarian adenosarcoma with extensive SCLEs. Both patients recovered well and the presence of SCLEs did not change the fate of the parent lesions. Our report highlights the importance of awareness of SCLEs in these Müllerian lesions, although exceedingly rare, to avoid diagnostic confusion.
ISSN:2772-736X
2772-736X
DOI:10.1016/j.hpr.2025.300799