An ensemble method for nuclei detection of overlapping cervical cells
The Pap test is a preventive approach that requires specialized and labor-intensive examination of cytological preparations to track potentially cancerous cells from the internal and external cervix surface. A cytopathologist must analyze many microscopic fields while screening for abnormal cells. T...
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| Vydáno v: | Expert systems with applications Ročník 185; s. 115642 |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
New York
Elsevier Ltd
15.12.2021
Elsevier BV Elsevier |
| Témata: | |
| ISSN: | 0957-4174, 1873-6793 |
| On-line přístup: | Získat plný text |
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| Shrnutí: | The Pap test is a preventive approach that requires specialized and labor-intensive examination of cytological preparations to track potentially cancerous cells from the internal and external cervix surface. A cytopathologist must analyze many microscopic fields while screening for abnormal cells. Therefore there is hope that a support decision system could assist with clinical diagnosis, for example, by identifying sub-cellular abnormalities, such as changes in the nuclei features. This work proposes an ensemble method for cervical nuclei detection aiming to reduce the workload of cytopathologists. First, a preprocessing phase divides the original image into superpixels, which are input to feature extraction and selection algorithms. The proposed ensemble method combines three classifiers: Decision Tree (DT), Nearest Centroid (NC), and k-Nearest Neighbors (k-NN), which are evaluated against the ISBI’14 Overlapping Cervical Cytology Image Segmentation Challenge dataset. Experiments show that the proposed method is the state-of-the-art algorithm of the literature for recall (0.999) and F1 values (0.993). It produced a recall very close to the optimum value and also kept high precision (0.988).
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•Ensemble of classifiers to provide a more assertive cervical cell nuclei segmentation.•Automatic inspection of Pap smear test to reduce the human workload in cervical cell analysis.•Superpixel computation and feature extraction to improve cell characterization and classification. |
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| Bibliografie: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 AC02-05CH11231 USDOE Office of Science (SC) |
| ISSN: | 0957-4174 1873-6793 |
| DOI: | 10.1016/j.eswa.2021.115642 |