An ensemble method for nuclei detection of overlapping cervical cells

The Pap test is a preventive approach that requires specialized and labor-intensive examination of cytological preparations to track potentially cancerous cells from the internal and external cervix surface. A cytopathologist must analyze many microscopic fields while screening for abnormal cells. T...

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Vydáno v:Expert systems with applications Ročník 185; s. 115642
Hlavní autoři: Diniz, Débora Nasser, Vitor, Rafael Ferreira, Bianchi, Andrea Gomes Campos, Delabrida, Saul, Carneiro, Cláudia Martins, Ushizima, Daniela Mayumi, de Medeiros, Fátima Nelsizeuma Sombra, Souza, Marcone Jamilson Freitas
Médium: Journal Article
Jazyk:angličtina
Vydáno: New York Elsevier Ltd 15.12.2021
Elsevier BV
Elsevier
Témata:
ISSN:0957-4174, 1873-6793
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Shrnutí:The Pap test is a preventive approach that requires specialized and labor-intensive examination of cytological preparations to track potentially cancerous cells from the internal and external cervix surface. A cytopathologist must analyze many microscopic fields while screening for abnormal cells. Therefore there is hope that a support decision system could assist with clinical diagnosis, for example, by identifying sub-cellular abnormalities, such as changes in the nuclei features. This work proposes an ensemble method for cervical nuclei detection aiming to reduce the workload of cytopathologists. First, a preprocessing phase divides the original image into superpixels, which are input to feature extraction and selection algorithms. The proposed ensemble method combines three classifiers: Decision Tree (DT), Nearest Centroid (NC), and k-Nearest Neighbors (k-NN), which are evaluated against the ISBI’14 Overlapping Cervical Cytology Image Segmentation Challenge dataset. Experiments show that the proposed method is the state-of-the-art algorithm of the literature for recall (0.999) and F1 values (0.993). It produced a recall very close to the optimum value and also kept high precision (0.988). [Display omitted] •Ensemble of classifiers to provide a more assertive cervical cell nuclei segmentation.•Automatic inspection of Pap smear test to reduce the human workload in cervical cell analysis.•Superpixel computation and feature extraction to improve cell characterization and classification.
Bibliografie:ObjectType-Article-1
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content type line 14
AC02-05CH11231
USDOE Office of Science (SC)
ISSN:0957-4174
1873-6793
DOI:10.1016/j.eswa.2021.115642