ChemRAP uncovers specific mRNA translation regulation via RNA 5′ phospho-methylation

5′-end modifications play key roles in determining RNA fates. Phospho-methylation is a noncanonical cap occurring on either 5′-PPP or 5′-P ends. We used ChemRAP, in which affinity purification of cellular proteins with chemically synthesized modified RNAs is coupled to quantitative proteomics, to id...

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Bibliographic Details

Published in:	EMBO reports Vol. 25; no. 3; pp. 1570 - 1588
Main Authors:	Ipas, Hélène, Gouws, Ellen B, Abell, Nathan S, Chiou, Po-Chin, Devanathan, Sravan K, Hervé, Solène, Lee, Sidae, Mercado, Marvin, Reinsborough, Calder, Halabelian, Levon, Arrowsmith, Cheryl H, Xhemalçe, Blerta
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 12.03.2024
Subjects:	Biomedical and Life Sciences EMBO32 EMBO36 Life Sciences BCDIN3D Local Translation RNA Modification Reader LRPPRC RNA Phospho-methylation
ISSN:	1469-3178, 1469-221X, 1469-3178
Online Access:	Get full text
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