Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence

Cellular senescence is a largely irreversible form of cell cycle arrest triggered by various types of damage and stress, including oncogene expression (termed oncogene-induced senescence or OIS). We and others have previously demonstrated that OIS occurs in human benign lesions, acting as a potent t...

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Veröffentlicht in:	Carcinogenesis (New York) Jg. 36; H. 11; S. 1263
Hauptverfasser:	Lenain, Christelle, Gusyatiner, Olga, Douma, Sirith, van den Broek, Bram, Peeper, Daniel S
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.11.2015
Schlagworte:	Autophagy Cell Line Cell Nucleus Shape Cellular Senescence Humans Nuclear Envelope - metabolism Nuclear Proteins - metabolism Oncogenes Proteolysis
ISSN:	1460-2180, 1460-2180
Online-Zugang:	Weitere Angaben
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