Temporal changes in postprandial blood transcriptomes reveal subject-specific pattern of expression of innate immunity genes after a high-fat meal

White blood cells are among the first responders to dietary components and their metabolites absorbed from the gut. The objective of this study was to determine the whole blood transcriptome response to high-fat challenge meals. A total of 45 fasting and postprandial (3-h and 6-h) whole blood transc...

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Bibliographic Details
Published in:	The Journal of nutritional biochemistry Vol. 72; p. 108209
Main Authors:	Lemay, Danielle G, Huang, Shurong, Huang, Liping, Alkan, Zeynep, Kirschke, Catherine, Burnett, Dustin J, Wang, Yining E, Hwang, Daniel H
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.10.2019
Subjects:	beta oxidation Biomarkers Blood transcriptome blueberries circadian rhythm digestive system docosahexaenoic acid fasting gene expression regulation genes high fat diet high fat foods High-fat Inflammation innate immunity leukocytes metabolites monitoring nutritional intervention placebos Postprandial receptors reverse transcriptase polymerase chain reaction RNA-Seq sequence analysis temporal variation transcriptome variance Biomarkers Inflammation High-fat Postprandial RNA-Seq Blood transcriptome
ISSN:	0955-2863, 1873-4847, 1873-4847
Online Access:	Get full text
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