Microbiota Promotes Chronic Pulmonary Inflammation by Enhancing IL-17A and Autoantibodies

Changes in the pulmonary microbiota are associated with progressive respiratory diseases including chronic obstructive pulmonary disease (COPD). Whether there is a causal relationship between these changes and disease progression remains unknown. To investigate the link between an altered microbiota...

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Bibliographic Details
Published in:	American journal of respiratory and critical care medicine Vol. 193; no. 9; pp. 975 - 987
Main Authors:	Yadava, Koshika, Pattaroni, Céline, Sichelstiel, Anke K., Trompette, Aurélien, Gollwitzer, Eva S., Salami, Olawale, von Garnier, Christophe, Nicod, Laurent P., Marsland, Benjamin J.
Format:	Journal Article
Language:	English
Published:	United States American Thoracic Society 01.05.2016
Subjects:	Animals Autoantibodies - immunology Disease Models, Animal Inflammation - complications Inflammation - immunology Inflammation - physiopathology Interleukin-17 - immunology Lung - immunology Lung - physiopathology Mice Mice, Inbred BALB C Microbiota Pulmonary Disease, Chronic Obstructive - complications Pulmonary Disease, Chronic Obstructive - immunology Pulmonary Disease, Chronic Obstructive - physiopathology microbiome; COPD; autoimmunity; IL-17
ISSN:	1073-449X, 1535-4970
Online Access:	Get full text
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