CAPRIN1/TYMS/MTHFD2 axis promotes EMT process in nasopharyngeal carcinoma development

Nasopharyngeal carcinoma (NPC) is a type of malignant tumor occurring in the nasopharynx. It frequently leads to treatment failure after metastasis, often resulting from epithelial-mesenchymal transition (EMT). Thymidylate synthetase (TYMS) is a key enzyme involved in DNA synthesis and replication....

Full description

Saved in:

Bibliographic Details
Published in:	The international journal of biochemistry & cell biology Vol. 185; p. 106784
Main Authors:	Wang, Kunrong, Yu, Hanbing, Guo, Shuang, Sun, Guihu, Cao, Hongwei, Xing, Dongsheng, Li, Dawei, Yan, Aihui
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01.08.2025
Subjects:	adjuvants Animals cadherins CAPRIN1 carcinoma caudal vein Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cell Line, Tumor Cell Movement DNA replication Epithelial Mesenchymal Transformation Epithelial-Mesenchymal Transition Gene Expression Regulation, Neoplastic Humans Lentivirus lungs metastasis Methylenetetrahydrofolate Dehydrogenase (NADP) - genetics Methylenetetrahydrofolate Dehydrogenase (NADP) - metabolism Mice Mice, Nude MTHFD2 Nasopharyngeal Carcinoma Nasopharyngeal Carcinoma - genetics Nasopharyngeal Carcinoma - metabolism Nasopharyngeal Carcinoma - pathology Nasopharyngeal Neoplasms - genetics Nasopharyngeal Neoplasms - metabolism Nasopharyngeal Neoplasms - pathology nasopharynx oxidoreductases plasmids precipitin tests RNA sequence analysis therapeutics thymidylate synthase Thymidylate Synthase - genetics Thymidylate Synthase - metabolism TYMS Epithelial Mesenchymal Transformation Nasopharyngeal Carcinoma TYMS MTHFD2 CAPRIN1
ISSN:	1357-2725, 1878-5875, 1878-5875
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!