CAPRIN1/TYMS/MTHFD2 axis promotes EMT process in nasopharyngeal carcinoma development

Nasopharyngeal carcinoma (NPC) is a type of malignant tumor occurring in the nasopharynx. It frequently leads to treatment failure after metastasis, often resulting from epithelial-mesenchymal transition (EMT). Thymidylate synthetase (TYMS) is a key enzyme involved in DNA synthesis and replication....

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Veröffentlicht in:	The international journal of biochemistry & cell biology Jg. 185; S. 106784
Hauptverfasser:	Wang, Kunrong, Yu, Hanbing, Guo, Shuang, Sun, Guihu, Cao, Hongwei, Xing, Dongsheng, Li, Dawei, Yan, Aihui
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier Ltd 01.08.2025
Schlagworte:	adjuvants Animals cadherins CAPRIN1 carcinoma caudal vein Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cell Line, Tumor Cell Movement DNA replication Epithelial Mesenchymal Transformation Epithelial-Mesenchymal Transition Gene Expression Regulation, Neoplastic Humans Lentivirus lungs metastasis Methylenetetrahydrofolate Dehydrogenase (NADP) - genetics Methylenetetrahydrofolate Dehydrogenase (NADP) - metabolism Mice Mice, Nude MTHFD2 Nasopharyngeal Carcinoma Nasopharyngeal Carcinoma - genetics Nasopharyngeal Carcinoma - metabolism Nasopharyngeal Carcinoma - pathology Nasopharyngeal Neoplasms - genetics Nasopharyngeal Neoplasms - metabolism Nasopharyngeal Neoplasms - pathology nasopharynx oxidoreductases plasmids precipitin tests RNA sequence analysis therapeutics thymidylate synthase Thymidylate Synthase - genetics Thymidylate Synthase - metabolism TYMS Epithelial Mesenchymal Transformation Nasopharyngeal Carcinoma TYMS MTHFD2 CAPRIN1
ISSN:	1357-2725, 1878-5875, 1878-5875
Online-Zugang:	Volltext
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