Outcomes of children with BCR-ABL1–like acute lymphoblastic leukemia treated with risk-directed therapy based on the levels of minimal residual disease

BCR-ABL1–like acute lymphoblastic leukemia (ALL) is a recently identified B-cell ALL (B-ALL)subtype with poor outcome that exhibits a gene expression profile similar to BCR-ABL1-positive ALL but lacks the BCR-ABL1 fusion protein. We examined the outcome of children with BCR-ABL1–like ALL treated wit...

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Bibliographic Details
Published in:	Journal of clinical oncology Vol. 32; no. 27; p. 3012
Main Authors:	Roberts, Kathryn G, Pei, Deqing, Campana, Dario, Payne-Turner, Debbie, Li, Yongjin, Cheng, Cheng, Sandlund, John T, Jeha, Sima, Easton, John, Becksfort, Jared, Zhang, Jinghui, Coustan-Smith, Elaine, Raimondi, Susana C, Leung, Wing H, Relling, Mary V, Evans, William E, Downing, James R, Mullighan, Charles G, Pui, Ching-Hon
Format:	Journal Article
Language:	English
Published:	United States 20.09.2014
Subjects:	Adolescent Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Child Child, Preschool Disease-Free Survival Female Fusion Proteins, bcr-abl - drug effects Fusion Proteins, bcr-abl - genetics Gene Expression Profiling Humans Infant Kaplan-Meier Estimate Male Molecular Targeted Therapy - methods Neoplasm, Residual - drug therapy Neoplasm, Residual - genetics Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology Risk Assessment Risk Factors Salvage Therapy - methods
ISSN:	1527-7755, 1527-7755
Online Access:	Get more information
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