A birth–death model to understand bacterial antimicrobial heteroresistance from time-kill curves

Antimicrobial heteroresistance refers to the presence of different subpopulations with heterogeneous antimicrobial responses within the same bacterial isolate, so they show reduced susceptibility compared with the main population. Though it is widely accepted that heteroresistance can play a crucial...

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Bibliographic Details

Published in:	Mathematical biosciences Vol. 376; p. 109278
Main Authors:	Martínez-López, Nerea, Vilas, Carlos, García, Míriam R.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.10.2024
Subjects:	AMR fitness cost Antimicrobial Resistance (AMR) Maximum Likelihood Estimation (MLE) Model identifiability Stochastic modelling Stochastic Simulation Algorithm (SSA) Stochastic Simulation Algorithm (SSA) Maximum Likelihood Estimation (MLE) Stochastic modelling AMR fitness cost Antimicrobial Resistance (AMR) Model identifiability
ISSN:	0025-5564, 1879-3134, 1879-3134
Online Access:	Get full text
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