Genetic Study of Psoriasis Highlights its Close Link with Socioeconomic Status and Affective Symptoms

Psoriasis is an inflammatory skin disease with an estimated heritability of around 70%. Previous GWASs have detected several risk loci for psoriasis. To further improve the understanding of the genetic risk factors impacting the disease, we conducted a discovery GWAS in FinnGen and a subsequent repl...

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Veröffentlicht in:	Journal of investigative dermatology Jg. 144; H. 12; S. 2719
Hauptverfasser:	Heikkilä, Anni, Sliz, Eeva, Huilaja, Laura, Reis, Kadri, Palta, Priit, Elnahas, Abdelrahman G, Reigo, Anu, Esko, Tõnu, Laisk, Triin, Teder-Laving, Maris, Tasanen, Kaisa, Kettunen, Johannes
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.12.2024
Schlagworte:	Affect Estonia - epidemiology Genetic Predisposition to Disease Genome-Wide Association Study Humans Polymorphism, Single Nucleotide Psoriasis - epidemiology Psoriasis - genetics Psoriasis - psychology Risk Factors Social Class UK Biobank - statistics & numerical data United Kingdom - epidemiology United Kingdom Estonia GWASs Human Genetics Psoriasis
ISSN:	1523-1747, 1523-1747
Online-Zugang:	Weitere Angaben
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