Proenkephalin expression and enkephalin release are widely observed in non-neuronal tissues

Enkephalins are opioid peptides that are found at high levels in the brain and endocrine tissues. Studies have shown that enkephalins play an important role in behavior, pain, cardiac function, cellular growth, immunity, and ischemic tolerance. Our global hypothesis is that enkephalins are released...

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Bibliographic Details
Published in:	Peptides (New York, N.Y. : 1980) Vol. 29; no. 1; pp. 83 - 92
Main Authors:	Denning, Gerene M., Ackermann, Laynez W., Barna, Thomas J., Armstrong, John G., Stoll, Lynn L., Weintraub, Neal L., Dickson, Eric W.
Format:	Journal Article
Language:	English
Published:	New York, NY Elsevier Inc 2008 Elsevier Science
Subjects:	Animals Biological and medical sciences Blotting, Western Enkephalins Enkephalins - biosynthesis Enkephalins - chemistry Enkephalins - genetics Enkephalins - metabolism Enzyme-Linked Immunosorbent Assay Epithelium - metabolism Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Profiling Heart - physiology Humans Intestines - cytology Intestines - metabolism Kidney - cytology Kidney - metabolism Male Mice Mice, Inbred C57BL Microscopy, Confocal Middle Aged Muscle, Skeletal - cytology Muscle, Skeletal - metabolism Muscle, Smooth - cytology Muscle, Smooth - metabolism Proenkephalin Protein Precursors - biosynthesis Protein Precursors - chemistry Protein Precursors - genetics Rats Rats, Sprague-Dawley Reverse Transcriptase Polymerase Chain Reaction - methods RNA, Messenger - genetics Skeletal muscle Striated muscle. Tendons Swine Vertebrates: endocrinology Vertebrates: osteoarticular system, musculoskeletal system Proenkephalin Gene expression Skeletal muscle Enkephalins Enkephalin Striated muscle Neuropeptide Opioid peptide Release
ISSN:	0196-9781, 1873-5169
Online Access:	Get full text
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