Influence of microvascular sutures on shear strain rate in realistic pulsatile flow

Arterial thrombus formation is directly related to the mechanical shear experienced by platelets within flow. High shear strain rates (SSRs) and large shear gradients cause platelet activation, aggregation and production of thrombus. This study, for the first time, investigates the influence of puls...

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Bibliographic Details
Published in:	Microvascular research Vol. 118; pp. 69 - 81
Main Authors:	Wain, R.A.J., Smith, D.J., Hammond, D.R., Whitty, J.P.M.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.07.2018
Subjects:	Anastomosis Anastomosis, Surgical Animals Arterial Occlusive Diseases - blood Arterial Occlusive Diseases - diagnostic imaging Arterial Occlusive Diseases - etiology Arterial Occlusive Diseases - physiopathology Blood Flow Velocity Chickens Computational Fluid Dynamics (CFD) Computer Simulation Female Femoral Artery - diagnostic imaging Femoral Artery - physiopathology Femoral Artery - surgery Humans Hydrodynamics Laser-Doppler Flowmetry Microvascular Models, Cardiovascular Platelet Aggregation Pulsatile Pulsatile Flow Regional Blood Flow Risk Factors Shear strain rate Stress, Mechanical Suture Techniques - adverse effects Suture Techniques - instrumentation Sutures Sutures - adverse effects Thrombosis - blood Thrombosis - diagnostic imaging Thrombosis - etiology Thrombosis - physiopathology Time Factors Sutures Microvascular Computational Fluid Dynamics (CFD) Shear strain rate Pulsatile Anastomosis
ISSN:	0026-2862, 1095-9319, 1095-9319
Online Access:	Get full text
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