Sex- and age-specific reference intervals of 16 steroid metabolites quantified simultaneously by LC-MS/MS in sera from 2458 healthy subjects aged 0 to 77 years

•A novel, specific, and sensitive isotope diluted LC-MS/MS method was developed for simultaneous quantitation of 16 steroid hormone metabolites.•Steroid metabolites in serum from healthy infants, children, adolescents, and adults aged 0.17 months to 77 years (n = 2458) were analysed.•Sex- and age sp...

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Bibliographic Details

Published in:	Clinica chimica acta Vol. 562; p. 119852
Main Authors:	Frederiksen, Hanne, Johannsen, Trine Holm, Andersen, Stine Ehlern, Petersen, Jørgen Holm, Busch, Alexander Siegfried, Ljubicic, Marie Lindhardt, Fischer, Margit Bistrup, Upners, Emmie N., Hagen, Casper P., Main, Katharina M., Aksglaede, Lise, Jørgensen, Niels, Lund Kårhus, Line, Linneberg, Allan, Andersson, Anna-Maria, Flück, Christa E., Juul, Anders
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 15.08.2024
Subjects:	Infant LC-MS/MS Puberty Reference interval Sex difference Steroid hormone Puberty LC-MS/MS Infant Reference interval Steroid hormone Sex difference
ISSN:	0009-8981, 1873-3492, 1873-3492
Online Access:	Get full text
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