Genome-Wide Analysis Identifies Two Susceptibility Loci for Positive Thyroid Peroxidase and Thyroglobulin Antibodies

Abstract Introduction Thyroid peroxidase (TPO) and thyroglobulin (Tg) are main components of the thyroid gland and play an essential role in thyroid hormone synthesis. The development of antibodies to thyroid peroxidase (TPOAb) and thyroglobulin (TgAb) is the major diagnostic hallmark and early indi...

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Vydané v:	The journal of clinical endocrinology and metabolism Ročník 105; číslo 3; s. 944 - 951
Hlavní autori:	Matana, Antonela, Boutin, Thibaud, Torlak, Vesela, Brdar, Dubravka, Gunjača, Ivana, Kolčić, Ivana, Boraska Perica, Vesna, Punda, Ante, Polašek, Ozren, Barbalić, Maja, Hayward, Caroline, Zemunik, Tatijana
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	US Oxford University Press 01.03.2020 Copyright Oxford University Press
Predmet:	Adult Aged Antibodies Autoantibodies - blood Autoantibodies - genetics Autoimmune diseases Croatia Female Genetic factors Genetic Loci Genetic Predisposition to Disease - genetics Genome-Wide Association Study Genomes Humans Interferon Regulatory Factors - genetics Iodide peroxidase Iodide Peroxidase - immunology Male Meta-analysis Middle Aged Proto-Oncogene Proteins c-yes - genetics Thyroglobulin Thyroglobulin - immunology Thyroid diseases Thyroid gland Thyroiditis, Autoimmune - blood Thyroiditis, Autoimmune - genetics Thyroiditis, Autoimmune - immunology Croatia meta-analysis thyroglobulin antibody thyroid peroxidase antibody genome-wide association study
ISSN:	0021-972X, 1945-7197, 1945-7197
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