Genome-Wide Analysis Identifies Two Susceptibility Loci for Positive Thyroid Peroxidase and Thyroglobulin Antibodies

Abstract Introduction Thyroid peroxidase (TPO) and thyroglobulin (Tg) are main components of the thyroid gland and play an essential role in thyroid hormone synthesis. The development of antibodies to thyroid peroxidase (TPOAb) and thyroglobulin (TgAb) is the major diagnostic hallmark and early indi...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism Jg. 105; H. 3; S. 944 - 951
Hauptverfasser:	Matana, Antonela, Boutin, Thibaud, Torlak, Vesela, Brdar, Dubravka, Gunjača, Ivana, Kolčić, Ivana, Boraska Perica, Vesna, Punda, Ante, Polašek, Ozren, Barbalić, Maja, Hayward, Caroline, Zemunik, Tatijana
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	US Oxford University Press 01.03.2020 Copyright Oxford University Press
Schlagworte:	Adult Aged Antibodies Autoantibodies - blood Autoantibodies - genetics Autoimmune diseases Croatia Female Genetic factors Genetic Loci Genetic Predisposition to Disease - genetics Genome-Wide Association Study Genomes Humans Interferon Regulatory Factors - genetics Iodide peroxidase Iodide Peroxidase - immunology Male Meta-analysis Middle Aged Proto-Oncogene Proteins c-yes - genetics Thyroglobulin Thyroglobulin - immunology Thyroid diseases Thyroid gland Thyroiditis, Autoimmune - blood Thyroiditis, Autoimmune - genetics Thyroiditis, Autoimmune - immunology Croatia meta-analysis thyroglobulin antibody thyroid peroxidase antibody genome-wide association study
ISSN:	0021-972X, 1945-7197, 1945-7197
Online-Zugang:	Volltext
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