Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops

Cytosine- and guanine-rich regions of DNA are capable of forming complex structures named i-motifs and G-quadruplexes, respectively. In the present study the solution equilibria at nearly physiological conditions of a 34-base long cytosine-rich sequence and its complementary guanine-rich strand corr...

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Bibliographic Details
Published in:	Biochimica et biophysica acta Vol. 1840; no. 1; pp. 41 - 52
Main Authors:	Benabou, Sanae, Ferreira, Rubén, Aviñó, Anna, González, Carlos, Lyonnais, Sébastien, Solà, Maria, Eritja, Ramon, Jaumot, Joaquim, Gargallo, Raimundo
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.01.2014
Subjects:	adenine Chromatography Chromatography, Gel Circular Dichroism cytosine Cytosine - chemistry DNA DNA - chemistry DNA - genetics G-quadruplex G-Quadruplexes Guanine - chemistry i-Motif introns mass spectrometry Models, Chemical Multivariate analysis n-myc oncogenes promoter regions Promoter Regions, Genetic Proto-Oncogene Proteins c-myc - chemistry Proto-Oncogene Proteins c-myc - genetics Quadruplex/duplex competition Solutions Spectrometry, Mass, Electrospray Ionization Quadruplex/duplex competition i-Motif n-myc Multivariate analysis Chromatography G-quadruplex
ISSN:	0304-4165, 0006-3002, 1872-8006
Online Access:	Get full text
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