Plant components can reduce methylmercury toxication: A mini-review

Methylmercury (MeHg) is a ubiquitous environmental pollutant, with the nervous system as its main target; however, the neurotoxic mechanisms of MeHg have not been fully elucidated, and no effective therapeutic and preventive drugs are available to mitigate its toxicity. Recent evidence suggests a re...

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Bibliographic Details
Published in:	Biochimica et biophysica acta. General subjects Vol. 1863; no. 12; p. 129290
Main Authors:	Chang, Jie, Zhou, Yun, Wang, Qiang, Aschner, Michael, Lu, Rongzhu
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.12.2019
Subjects:	absorption Animals biochemical mechanisms demethylation drugs excretion Humans intestines mercury Methylmercury methylmercury compounds Methylmercury Compounds - pharmacokinetics Methylmercury Compounds - toxicity Natural plant components nervous system Neuroprotective Agents - chemistry Neuroprotective Agents - pharmacokinetics neurotoxicity Neurotoxicity Syndromes - drug therapy Neurotoxicity Syndromes - metabolism Neurotoxicity Syndromes - pathology plant extracts Plant Extracts - chemistry Plant Extracts - pharmacokinetics Plant Extracts - therapeutic use Plant Structures - chemistry pollutants protective effect therapeutics tissues Toxicity Cd CDC Toxicity CNS HO-1 MDA UC FFQ LDH bw Nrf2 CGNs Methylmercury BME GD GSH EpRE Hg DTPA hNSCs i.g GEE SOD i.p TBARS Natural plant components DMPS BAL GPx MeHg ARE Trolox CAT LC NMDA-R ROS LBPs POEE TP ADA DC
ISSN:	0304-4165, 1872-8006, 1872-8006
Online Access:	Get full text
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