Sub-wavelength grating for enhanced ring resonator biosensor
While silicon photonic resonant cavities have been widely investigated for biosensing applications, enhancing their sensitivity and detection limit continues to be an area of active research. Here, we describe how to engineer the effective refractive index and mode profile of a silicon-on-insulator...
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| Vydané v: | Optics express Ročník 24; číslo 14; s. 15672 - 15686 |
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| Hlavní autori: | , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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United States
11.07.2016
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| ISSN: | 1094-4087, 1094-4087 |
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| Abstract | While silicon photonic resonant cavities have been widely investigated for biosensing applications, enhancing their sensitivity and detection limit continues to be an area of active research. Here, we describe how to engineer the effective refractive index and mode profile of a silicon-on-insulator (SOI) waveguide using sub-wavelength gratings (SWG) and report on its observed performance as a biosensor. We designed a 30 μm diameter SWG ring resonator and fabricated it using Ebeam lithography. Its characterization resulted in a quality factor, Q, of 7 · 10
, bulk sensitivity Sb = 490 nm/RIU, and system limit of detection sLoD = 2 · 10
RIU. Finally we employ a model biological sandwich assay to demonstrate its utility for biosensing applications. |
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| AbstractList | While silicon photonic resonant cavities have been widely investigated for biosensing applications, enhancing their sensitivity and detection limit continues to be an area of active research. Here, we describe how to engineer the effective refractive index and mode profile of a silicon-on-insulator (SOI) waveguide using sub-wavelength gratings (SWG) and report on its observed performance as a biosensor. We designed a 30 μm diameter SWG ring resonator and fabricated it using Ebeam lithography. Its characterization resulted in a quality factor, Q, of 7 · 103, bulk sensitivity Sb = 490 nm/RIU, and system limit of detection sLoD = 2 · 10-6 RIU. Finally we employ a model biological sandwich assay to demonstrate its utility for biosensing applications. While silicon photonic resonant cavities have been widely investigated for biosensing applications, enhancing their sensitivity and detection limit continues to be an area of active research. Here, we describe how to engineer the effective refractive index and mode profile of a silicon-on-insulator (SOI) waveguide using sub-wavelength gratings (SWG) and report on its observed performance as a biosensor. We designed a 30 μm diameter SWG ring resonator and fabricated it using Ebeam lithography. Its characterization resulted in a quality factor, Q, of 7 · 10 , bulk sensitivity Sb = 490 nm/RIU, and system limit of detection sLoD = 2 · 10 RIU. Finally we employ a model biological sandwich assay to demonstrate its utility for biosensing applications. |
| Author | Sherwali, Ahmed Ratner, Daniel M. Schmidt, Shon Donzella, Valentina Flueckiger, Jonas Chrostowski, Lukas Cheung, Karen C. |
| Author_xml | – sequence: 1 givenname: Jonas surname: Flueckiger fullname: Flueckiger, Jonas – sequence: 2 givenname: Shon surname: Schmidt fullname: Schmidt, Shon – sequence: 3 givenname: Valentina surname: Donzella fullname: Donzella, Valentina – sequence: 4 givenname: Ahmed surname: Sherwali fullname: Sherwali, Ahmed – sequence: 5 givenname: Daniel M. surname: Ratner fullname: Ratner, Daniel M. – sequence: 6 givenname: Lukas surname: Chrostowski fullname: Chrostowski, Lukas – sequence: 7 givenname: Karen C. surname: Cheung fullname: Cheung, Karen C. |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27410840$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1080/09500349414550371 10.1364/OL.39.005519 10.1116/1.3653266 10.1364/OE.18.016146 10.1364/AO.36.001218 10.1016/j.snb.2005.03.043 10.1364/OE.22.020652 10.1002/ange.201001712 10.1073/pnas.0808988106 10.1016/j.bios.2011.10.056 10.1016/0161-5890(81)90098-5 10.1021/ac902006p 10.1103/PhysRevLett.98.243901 10.1364/OE.18.003226 10.1364/OE.21.007994 10.1002/lpor.201400083 10.1126/science.1145002 10.1364/OE.23.004791 10.1364/OE.15.007610 10.1364/OL.33.000708 10.1364/OE.17.015330 10.1109/50.469728 10.1364/OE.20.019912 10.1364/OE.18.020251 10.1006/jcis.2000.7240 10.1016/j.bios.2010.07.010 10.1364/OE.22.015335 10.1109/50.887192 10.1529/biophysj.103.030072 10.1016/j.bios.2012.10.079 10.1364/OE.22.021037 10.1364/OL.39.004442 10.1002/jbio.201200067 10.1364/OE.22.002807 10.1364/OE.22.014166 10.1038/nphoton.2010.179 10.1364/OL.17.001195 10.1109/JSTQE.2006.883151 10.1109/JSTQE.2009.2032510 10.1038/nphoton.2010.172 10.1364/OE.14.004695 10.1515/nanoph-2013-0021 10.1109/JPHOT.2009.2031596 10.1038/nnano.2011.44 10.1016/S0927-7765(01)00236-3 10.1364/OE.18.019541 10.1016/j.bios.2009.01.009 10.1039/c1lc20231f 10.1116/1.585183 |
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| References | Luchansky (oe-24-14-15672-R13) 2010; 26 Hochberg (oe-24-14-15672-R2) 2010; 4 Loncar (oe-24-14-15672-R43) 2000; 18 Gonzalo Wangüemert-Pérez (oe-24-14-15672-R34) 2014; 39 Prabhathan (oe-24-14-15672-R10) 2009; 17 Luchansky (oe-24-14-15672-R23) 2011; 11 Wang (oe-24-14-15672-R44) 2014; 39 Liu (oe-24-14-15672-R12) 2012; 20 Washburn (oe-24-14-15672-R15) 2009; 81 Weissman (oe-24-14-15672-R37) 1995; 13 Arlett (oe-24-14-15672-R22) 2011; 6 De Vos (oe-24-14-15672-R6) 2009; 24 Li (oe-24-14-15672-R41) 1992; 17 Donzella (oe-24-14-15672-R35) 2015; 23 Vörös (oe-24-14-15672-R47) 2004; 87 Levy (oe-24-14-15672-R32) 2007; 98 Armani (oe-24-14-15672-R8) 2007; 317 Wang (oe-24-14-15672-R11) 2013; 6 Claes (oe-24-14-15672-R27) 2009; 1 Cheben (oe-24-14-15672-R30) 2006; 14 Bock (oe-24-14-15672-R38) 2010; 18 Bojko (oe-24-14-15672-R45) 2011; 29 Grist (oe-24-14-15672-R7) 2013; 21 Wang (oe-24-14-15672-R33) 2014; 22 Vollmer (oe-24-14-15672-R17) 2008; 105 Rodriguez-Mozaz (oe-24-14-15672-R19) 2005; 65 Bock (oe-24-14-15672-R28) 2010; 18 Soref (oe-24-14-15672-R1) 2006; 12 Halir (oe-24-14-15672-R29) 2015; 9 Donzella (oe-24-14-15672-R42) 2014; 22 Reed (oe-24-14-15672-R4) 2010; 4 Kirk (oe-24-14-15672-R16) 2013; 42 Dai (oe-24-14-15672-R3) 2014; 3 Gylfason (oe-24-14-15672-R25) 2010; 18 Nikitin (oe-24-14-15672-R48) 2005; 111 Iqbal (oe-24-14-15672-R5) 2010; 16 Rytov (oe-24-14-15672-R36) 1956; 2 Fard (oe-24-14-15672-R24) 2014; 22 Qavi (oe-24-14-15672-R14) 2010; 122 Hoste (oe-24-14-15672-R20) 2014; 22 Wang (oe-24-14-15672-R31) 2014; 22 Dowling (oe-24-14-15672-R39) 1994; 41 Höök (oe-24-14-15672-R49) 2002; 24 Coen (oe-24-14-15672-R46) 2001; 233 Bojko (oe-24-14-15672-R50) 1990; 8 Weissman (oe-24-14-15672-R40) 1997; 36 Mota (oe-24-14-15672-R51) 1981; 18 De Vos (oe-24-14-15672-R21) 2007; 15 Barrios (oe-24-14-15672-R26) 2008; 33 Soltani (oe-24-14-15672-R9) 2010; 18 McClellan (oe-24-14-15672-R18) 2012; 31 |
| References_xml | – volume: 41 start-page: 345 year: 1994 ident: oe-24-14-15672-R39 publication-title: J. Mod. Opt. doi: 10.1080/09500349414550371 – volume: 39 start-page: 5519 year: 2014 ident: oe-24-14-15672-R44 publication-title: Opt. Lett. doi: 10.1364/OL.39.005519 – volume: 29 start-page: 06F year: 2011 ident: oe-24-14-15672-R45 publication-title: J. Vac. Sci. Technol., B doi: 10.1116/1.3653266 – volume: 18 start-page: 16146 year: 2010 ident: oe-24-14-15672-R28 publication-title: Opt. Express doi: 10.1364/OE.18.016146 – volume: 36 start-page: 1218 year: 1997 ident: oe-24-14-15672-R40 publication-title: Appl. Opt. doi: 10.1364/AO.36.001218 – volume: 111 start-page: 500 year: 2005 ident: oe-24-14-15672-R48 publication-title: Sens. Actuators, B doi: 10.1016/j.snb.2005.03.043 – volume: 22 start-page: 20652 year: 2014 ident: oe-24-14-15672-R31 publication-title: Opt. Express doi: 10.1364/OE.22.020652 – volume: 122 start-page: 4712 year: 2010 ident: oe-24-14-15672-R14 publication-title: Angew. Chem. doi: 10.1002/ange.201001712 – volume: 105 start-page: 20701 year: 2008 ident: oe-24-14-15672-R17 publication-title: Proc. Natl. Acad. Sci doi: 10.1073/pnas.0808988106 – volume: 31 start-page: 388 year: 2012 ident: oe-24-14-15672-R18 publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2011.10.056 – volume: 18 start-page: 373 year: 1981 ident: oe-24-14-15672-R51 publication-title: Mol. Immunol. doi: 10.1016/0161-5890(81)90098-5 – volume: 81 start-page: 9499 year: 2009 ident: oe-24-14-15672-R15 publication-title: Anal. Chem. doi: 10.1021/ac902006p – volume: 98 start-page: 243901 year: 2007 ident: oe-24-14-15672-R32 publication-title: Phys. Rev. Lett. doi: 10.1103/PhysRevLett.98.243901 – volume: 18 start-page: 3226 year: 2010 ident: oe-24-14-15672-R25 publication-title: Opt. Express doi: 10.1364/OE.18.003226 – volume: 21 start-page: 7994 year: 2013 ident: oe-24-14-15672-R7 publication-title: Opt. Express doi: 10.1364/OE.21.007994 – volume: 9 start-page: 25 year: 2015 ident: oe-24-14-15672-R29 publication-title: Laser Photon. Rev. doi: 10.1002/lpor.201400083 – volume: 317 start-page: 783 year: 2007 ident: oe-24-14-15672-R8 publication-title: Science doi: 10.1126/science.1145002 – volume: 23 start-page: 4791 year: 2015 ident: oe-24-14-15672-R35 publication-title: Opt. Express doi: 10.1364/OE.23.004791 – volume: 15 start-page: 7610 year: 2007 ident: oe-24-14-15672-R21 publication-title: Opt. Express doi: 10.1364/OE.15.007610 – volume: 33 start-page: 708 year: 2008 ident: oe-24-14-15672-R26 publication-title: Opt. Lett. doi: 10.1364/OL.33.000708 – volume: 17 start-page: 15330 year: 2009 ident: oe-24-14-15672-R10 publication-title: Opt. Express doi: 10.1364/OE.17.015330 – volume: 13 start-page: 2053 year: 1995 ident: oe-24-14-15672-R37 publication-title: J. Lightwave Technol. doi: 10.1109/50.469728 – volume: 2 start-page: 466 year: 1956 ident: oe-24-14-15672-R36 publication-title: Soviet Physics JETP-USSR – volume: 20 start-page: 19912 year: 2012 ident: oe-24-14-15672-R12 publication-title: Opt. Express doi: 10.1364/OE.20.019912 – volume: 18 start-page: 20251 year: 2010 ident: oe-24-14-15672-R38 publication-title: Opt. Express doi: 10.1364/OE.18.020251 – volume: 233 start-page: 180 year: 2001 ident: oe-24-14-15672-R46 publication-title: J. ColloidInterface Sci. doi: 10.1006/jcis.2000.7240 – volume: 26 start-page: 1283 year: 2010 ident: oe-24-14-15672-R13 publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2010.07.010 – volume: 22 start-page: 15335 year: 2014 ident: oe-24-14-15672-R33 publication-title: Opt. Express doi: 10.1364/OE.22.015335 – volume: 18 start-page: 1402 year: 2000 ident: oe-24-14-15672-R43 publication-title: J. Lightwave Technol. doi: 10.1109/50.887192 – volume: 87 start-page: 553 year: 2004 ident: oe-24-14-15672-R47 publication-title: Biophys. J. doi: 10.1529/biophysj.103.030072 – volume: 42 start-page: 100 year: 2013 ident: oe-24-14-15672-R16 publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2012.10.079 – volume: 65 start-page: 291 year: 2005 ident: oe-24-14-15672-R19 publication-title: Talanta – volume: 22 start-page: 21037 year: 2014 ident: oe-24-14-15672-R42 publication-title: Opt. Express doi: 10.1364/OE.22.021037 – volume: 39 start-page: 4442 year: 2014 ident: oe-24-14-15672-R34 publication-title: Opt. Lett. doi: 10.1364/OL.39.004442 – volume: 6 start-page: 821 year: 2013 ident: oe-24-14-15672-R11 publication-title: J. Biophotonics doi: 10.1002/jbio.201200067 – volume: 22 start-page: 2807 year: 2014 ident: oe-24-14-15672-R20 publication-title: Opt. Express doi: 10.1364/OE.22.002807 – volume: 22 start-page: 14166 year: 2014 ident: oe-24-14-15672-R24 publication-title: Opt. Express doi: 10.1364/OE.22.014166 – volume: 4 start-page: 518 year: 2010 ident: oe-24-14-15672-R4 publication-title: Nat. Photonics doi: 10.1038/nphoton.2010.179 – volume: 17 start-page: 1195 year: 1992 ident: oe-24-14-15672-R41 publication-title: Opt. Lett. doi: 10.1364/OL.17.001195 – volume: 12 start-page: 1678 year: 2006 ident: oe-24-14-15672-R1 publication-title: IEEE J. Sel. Topics Quantum Electron doi: 10.1109/JSTQE.2006.883151 – volume: 16 start-page: 654 year: 2010 ident: oe-24-14-15672-R5 publication-title: IEEE J. Sel. Topics Quantum Electron doi: 10.1109/JSTQE.2009.2032510 – volume: 4 start-page: 492 year: 2010 ident: oe-24-14-15672-R2 publication-title: Nat. Photonics doi: 10.1038/nphoton.2010.172 – volume: 14 start-page: 4695 year: 2006 ident: oe-24-14-15672-R30 publication-title: Opt. Express doi: 10.1364/OE.14.004695 – volume: 3 start-page: 283 year: 2014 ident: oe-24-14-15672-R3 publication-title: Nanophotonics doi: 10.1515/nanoph-2013-0021 – volume: 1 start-page: 197 year: 2009 ident: oe-24-14-15672-R27 publication-title: IEEE Photon. J. doi: 10.1109/JPHOT.2009.2031596 – volume: 6 start-page: 203 year: 2011 ident: oe-24-14-15672-R22 publication-title: Nat. Nanotechnol. doi: 10.1038/nnano.2011.44 – volume: 24 start-page: 155 year: 2002 ident: oe-24-14-15672-R49 publication-title: Colloids Surf., B doi: 10.1016/S0927-7765(01)00236-3 – volume: 18 start-page: 19541 year: 2010 ident: oe-24-14-15672-R9 publication-title: Opt. Express doi: 10.1364/OE.18.019541 – volume: 24 start-page: 2528 year: 2009 ident: oe-24-14-15672-R6 publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2009.01.009 – volume: 11 start-page: 2042 year: 2011 ident: oe-24-14-15672-R23 publication-title: Lab Chip doi: 10.1039/c1lc20231f – volume: 8 start-page: 1909 year: 1990 ident: oe-24-14-15672-R50 publication-title: J. Vac. Sci. Technol., B doi: 10.1116/1.585183 |
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| Snippet | While silicon photonic resonant cavities have been widely investigated for biosensing applications, enhancing their sensitivity and detection limit continues... |
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| SubjectTerms | Biosensing Techniques - instrumentation Equipment Design Limit of Detection Optics and Photonics Photons Refractometry Silicon |
| Title | Sub-wavelength grating for enhanced ring resonator biosensor |
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