Oral Fluoride Levels 1 h after Use of a Sodium Fluoride Rinse: Effect of Sodium Lauryl Sulfate

Increasing the concentration of free fluoride in oral fluids is an important goal in the use of topical fluoride agents. Although sodium lauryl sulfate (SLS) is a common dentifrice ingredient, the influence of this ion on plaque fluid and salivary fluid fluoride has not been examined. The purpose of...

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Vydáno v:Caries research Ročník 49; číslo 3; s. 291 - 296
Hlavní autoři: Vogel, Gerald L., Schumacher, Gary E., Chow, Laurence C., Tenuta, Livia M.A.
Médium: Journal Article
Jazyk:angličtina
Vydáno: Basel, Switzerland S. Karger AG 01.05.2015
Témata:
Adult
Calcium - analysis
Calcium - pharmacokinetics
Cariostatic Agents - analysis
Cariostatic Agents - pharmacokinetics
Cariostatic Agents - therapeutic use
Dental Plaque - chemistry
Dental Plaque - metabolism
Female
Fluorides - analysis
Fluorides - pharmacokinetics
Humans
Ion-Selective Electrodes
Male
Middle Aged
Mouthwashes - therapeutic use
Original Paper
Saliva - chemistry
Saliva - metabolism
Sodium Dodecyl Sulfate - pharmacology
Sodium Fluoride - therapeutic use
Surface-Active Agents - pharmacology
Fluoride
Sodium lauryl sulfate
Plaque fluid
Saliva
Plaque
ISSN:0008-6568, 1421-976X, 1421-976X
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Shrnutí:Increasing the concentration of free fluoride in oral fluids is an important goal in the use of topical fluoride agents. Although sodium lauryl sulfate (SLS) is a common dentifrice ingredient, the influence of this ion on plaque fluid and salivary fluid fluoride has not been examined. The purpose of this study was to investigate the effect of SLS on these parameters and to examine the effect of this ion on total (or whole) plaque fluoride, an important source of plaque fluid fluoride after a sufficient interval following fluoride administration, and on total salivary fluoride, a parameter often used as a surrogate measure of salivary fluid fluoride. Ten subjects accumulated plaque for 48 h before rinsing with a 12 mmol/l NaF (228 µg/g F) rinse containing or not containing 0.5% (w/w) SLS. SLS had no statistically significant effect on total plaque and total saliva fluoride but significantly increased salivary fluid and plaque fluid fluoride (by 147 and 205%, respectively). These results suggest that the nonfluoride components of topical agents can be manipulated to improve the fluoride release characteristics from oral fluoride reservoirs and that statistically significant change may be observed in plaque fluid and salivary fluid fluoride concentrations that may not be observed in total plaque and total saliva fluoride concentrations.
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ISSN:0008-6568
1421-976X
1421-976X
DOI:10.1159/000381192