Glyco-genes change expression in cancer through aberrant methylation
Most eukaryotic proteins are modified by covalent addition of glycan molecules that considerably influence their function. Aberrant glycosylation is profoundly involved in malignant transformation, tumor progression and metastasis. Some glycan structures are tumor-specific and reflect disturbed glyc...
Saved in:
| Published in: | Biochimica et biophysica acta Vol. 1860; no. 8; pp. 1776 - 1785 |
|---|---|
| Main Authors: | , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Netherlands
Elsevier B.V
01.08.2016
|
| Subjects: | |
| ISSN: | 0304-4165, 0006-3002, 1872-8006 |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | Most eukaryotic proteins are modified by covalent addition of glycan molecules that considerably influence their function. Aberrant glycosylation is profoundly involved in malignant transformation, tumor progression and metastasis. Some glycan structures are tumor-specific and reflect disturbed glycan biosynthesis pathways.
We analyzed DNA methylation and expression of 86 glyco-genes in melanoma, hepatocellular, breast and cervical cancers using data from publicly available databases. We also analyzed methylation datasets without the available matching expression data for glyco-genes in lung cancer, and progression of melanoma into lymph node and brain metastases.
Ten glyco-genes (GALNT3, GALNT6, GALNT7, GALNT14, MGAT3, MAN1A1, MAN1C1, ST3GAL2, ST6GAL1, ST8SIA3) showing changes in both methylation and expression in the same type of cancer belong to GalNAc transferases, GlcNAc transferases, mannosidases and sialyltransferases, which is in line with changes in glycan structures already reported in the same type of tumors. Some of those genes were additionally identified as potentially valuable for disease prognosis. The MGAT5B gene, so far identified as specifically expressed in brain, emerged as a novel candidate gene that is epigenetically dysregulated in different cancers other than brain cancer. We also report for the first time aberrant expression of the GALNT and MAN genes in cancer by aberrant promoter methylation.
Aberrant expression of glyco-genes due to aberrant promoter methylation could be a way leading to characteristic glycosylation profiles commonly described in cancer.
Methylation status in promoters of candidate glyco-genes might serve as prognostic markers for specific tumors and point to potential novel targets for epigenetic drugs.
This article is part of a Special Issue entitled "Glycans in personalised medicine" Guest Editor: Professor Gordan Lauc.
•Identification of glyco-genes showing changed expression and methylation in different types of cancer•A subset of ten glyco-genes consistently shows both aberrant expression and CpG methylation•Some of the identified genes show potential as prognostic markers in certain types of cancer. |
|---|---|
| AbstractList | Most eukaryotic proteins are modified by covalent addition of glycan molecules that considerably influence their function. Aberrant glycosylation is profoundly involved in malignant transformation, tumor progression and metastasis. Some glycan structures are tumor-specific and reflect disturbed glycan biosynthesis pathways.
We analyzed DNA methylation and expression of 86 glyco-genes in melanoma, hepatocellular, breast and cervical cancers using data from publicly available databases. We also analyzed methylation datasets without the available matching expression data for glyco-genes in lung cancer, and progression of melanoma into lymph node and brain metastases.
Ten glyco-genes (GALNT3, GALNT6, GALNT7, GALNT14, MGAT3, MAN1A1, MAN1C1, ST3GAL2, ST6GAL1, ST8SIA3) showing changes in both methylation and expression in the same type of cancer belong to GalNAc transferases, GlcNAc transferases, mannosidases and sialyltransferases, which is in line with changes in glycan structures already reported in the same type of tumors. Some of those genes were additionally identified as potentially valuable for disease prognosis. The MGAT5B gene, so far identified as specifically expressed in brain, emerged as a novel candidate gene that is epigenetically dysregulated in different cancers other than brain cancer. We also report for the first time aberrant expression of the GALNT and MAN genes in cancer by aberrant promoter methylation.
Aberrant expression of glyco-genes due to aberrant promoter methylation could be a way leading to characteristic glycosylation profiles commonly described in cancer.
Methylation status in promoters of candidate glyco-genes might serve as prognostic markers for specific tumors and point to potential novel targets for epigenetic drugs. This article is part of a Special Issue entitled "Glycans in personalised medicine" Guest Editor: Professor Gordan Lauc. Most eukaryotic proteins are modified by covalent addition of glycan molecules that considerably influence their function. Aberrant glycosylation is profoundly involved in malignant transformation, tumor progression and metastasis. Some glycan structures are tumor-specific and reflect disturbed glycan biosynthesis pathways.We analyzed DNA methylation and expression of 86 glyco-genes in melanoma, hepatocellular, breast and cervical cancers using data from publicly available databases. We also analyzed methylation datasets without the available matching expression data for glyco-genes in lung cancer, and progression of melanoma into lymph node and brain metastases.Ten glyco-genes (GALNT3, GALNT6, GALNT7, GALNT14, MGAT3, MAN1A1, MAN1C1, ST3GAL2, ST6GAL1, ST8SIA3) showing changes in both methylation and expression in the same type of cancer belong to GalNAc transferases, GlcNAc transferases, mannosidases and sialyltransferases, which is in line with changes in glycan structures already reported in the same type of tumors. Some of those genes were additionally identified as potentially valuable for disease prognosis. The MGAT5B gene, so far identified as specifically expressed in brain, emerged as a novel candidate gene that is epigenetically dysregulated in different cancers other than brain cancer. We also report for the first time aberrant expression of the GALNT and MAN genes in cancer by aberrant promoter methylation.Aberrant expression of glyco-genes due to aberrant promoter methylation could be a way leading to characteristic glycosylation profiles commonly described in cancer.Methylation status in promoters of candidate glyco-genes might serve as prognostic markers for specific tumors and point to potential novel targets for epigenetic drugs.This article is part of a Special Issue entitled "Glycans in personalised medicine" Guest Editor: Professor Gordan Lauc. Most eukaryotic proteins are modified by covalent addition of glycan molecules that considerably influence their function. Aberrant glycosylation is profoundly involved in malignant transformation, tumor progression and metastasis. Some glycan structures are tumor-specific and reflect disturbed glycan biosynthesis pathways. We analyzed DNA methylation and expression of 86 glyco-genes in melanoma, hepatocellular, breast and cervical cancers using data from publicly available databases. We also analyzed methylation datasets without the available matching expression data for glyco-genes in lung cancer, and progression of melanoma into lymph node and brain metastases. Ten glyco-genes (GALNT3, GALNT6, GALNT7, GALNT14, MGAT3, MAN1A1, MAN1C1, ST3GAL2, ST6GAL1, ST8SIA3) showing changes in both methylation and expression in the same type of cancer belong to GalNAc transferases, GlcNAc transferases, mannosidases and sialyltransferases, which is in line with changes in glycan structures already reported in the same type of tumors. Some of those genes were additionally identified as potentially valuable for disease prognosis. The MGAT5B gene, so far identified as specifically expressed in brain, emerged as a novel candidate gene that is epigenetically dysregulated in different cancers other than brain cancer. We also report for the first time aberrant expression of the GALNT and MAN genes in cancer by aberrant promoter methylation. Aberrant expression of glyco-genes due to aberrant promoter methylation could be a way leading to characteristic glycosylation profiles commonly described in cancer. Methylation status in promoters of candidate glyco-genes might serve as prognostic markers for specific tumors and point to potential novel targets for epigenetic drugs. This article is part of a Special Issue entitled "Glycans in personalised medicine" Guest Editor: Professor Gordan Lauc. •Identification of glyco-genes showing changed expression and methylation in different types of cancer•A subset of ten glyco-genes consistently shows both aberrant expression and CpG methylation•Some of the identified genes show potential as prognostic markers in certain types of cancer. Most eukaryotic proteins are modified by covalent addition of glycan molecules that considerably influence their function. Aberrant glycosylation is profoundly involved in malignant transformation, tumor progression and metastasis. Some glycan structures are tumor-specific and reflect disturbed glycan biosynthesis pathways.BACKGROUNDMost eukaryotic proteins are modified by covalent addition of glycan molecules that considerably influence their function. Aberrant glycosylation is profoundly involved in malignant transformation, tumor progression and metastasis. Some glycan structures are tumor-specific and reflect disturbed glycan biosynthesis pathways.We analyzed DNA methylation and expression of 86 glyco-genes in melanoma, hepatocellular, breast and cervical cancers using data from publicly available databases. We also analyzed methylation datasets without the available matching expression data for glyco-genes in lung cancer, and progression of melanoma into lymph node and brain metastases.METHODSWe analyzed DNA methylation and expression of 86 glyco-genes in melanoma, hepatocellular, breast and cervical cancers using data from publicly available databases. We also analyzed methylation datasets without the available matching expression data for glyco-genes in lung cancer, and progression of melanoma into lymph node and brain metastases.Ten glyco-genes (GALNT3, GALNT6, GALNT7, GALNT14, MGAT3, MAN1A1, MAN1C1, ST3GAL2, ST6GAL1, ST8SIA3) showing changes in both methylation and expression in the same type of cancer belong to GalNAc transferases, GlcNAc transferases, mannosidases and sialyltransferases, which is in line with changes in glycan structures already reported in the same type of tumors. Some of those genes were additionally identified as potentially valuable for disease prognosis. The MGAT5B gene, so far identified as specifically expressed in brain, emerged as a novel candidate gene that is epigenetically dysregulated in different cancers other than brain cancer. We also report for the first time aberrant expression of the GALNT and MAN genes in cancer by aberrant promoter methylation.RESULTSTen glyco-genes (GALNT3, GALNT6, GALNT7, GALNT14, MGAT3, MAN1A1, MAN1C1, ST3GAL2, ST6GAL1, ST8SIA3) showing changes in both methylation and expression in the same type of cancer belong to GalNAc transferases, GlcNAc transferases, mannosidases and sialyltransferases, which is in line with changes in glycan structures already reported in the same type of tumors. Some of those genes were additionally identified as potentially valuable for disease prognosis. The MGAT5B gene, so far identified as specifically expressed in brain, emerged as a novel candidate gene that is epigenetically dysregulated in different cancers other than brain cancer. We also report for the first time aberrant expression of the GALNT and MAN genes in cancer by aberrant promoter methylation.Aberrant expression of glyco-genes due to aberrant promoter methylation could be a way leading to characteristic glycosylation profiles commonly described in cancer.CONCLUSIONSAberrant expression of glyco-genes due to aberrant promoter methylation could be a way leading to characteristic glycosylation profiles commonly described in cancer.Methylation status in promoters of candidate glyco-genes might serve as prognostic markers for specific tumors and point to potential novel targets for epigenetic drugs. This article is part of a Special Issue entitled "Glycans in personalised medicine" Guest Editor: Professor Gordan Lauc.GENERAL SIGNIFICANCEMethylation status in promoters of candidate glyco-genes might serve as prognostic markers for specific tumors and point to potential novel targets for epigenetic drugs. This article is part of a Special Issue entitled "Glycans in personalised medicine" Guest Editor: Professor Gordan Lauc. |
| Author | Samaržija, Ivana Bočkor, Luka Vojta, Aleksandar Zoldoš, Vlatka |
| Author_xml | – sequence: 1 givenname: Aleksandar surname: Vojta fullname: Vojta, Aleksandar – sequence: 2 givenname: Ivana surname: Samaržija fullname: Samaržija, Ivana – sequence: 3 givenname: Luka surname: Bočkor fullname: Bočkor, Luka – sequence: 4 givenname: Vlatka surname: Zoldoš fullname: Zoldoš, Vlatka email: vzoldos@biol.pmf.hr |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26794090$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkU1v1DAQhi1URLeFf4BQjlwSxt8xByRUaEGqxAXOlmNPdr3KOoudrdh_j9ttLxyoLyNLz_tKM88FOUtzQkLeUugoUPVh2w2DW2PqWP11QDsA9oKsaK9Z2wOoM7ICDqIVVMlzclHKFuqTRr4i50xpI8DAiny5mY5-bmsPlsZvXFpjg3_2GUuJc2piarxLHnOzbPJ8WG8aN2DOLi3NDpfNcXJLxV6Tl6ObCr55nJfk1_XXn1ff2tsfN9-vPt-2nhu5tJw7HAftQm-MUCBRiaAd6zUGYdgI3ID3QfUhgFbOh0EJx7TiYxiZ8SD5JXl_6t3n-fcBy2J3sXicJpdwPhRLeyYFl0Ka51FtNOMSelbRd4_oYdhhsPscdy4f7dORKvDxBPg8l5JxtD4uD4sv2cXJUrD3RuzWnozYeyMWqK1Galj8E37qfyb26RTDes-7iNkWH7GaCDGjX2yY4_8L_gLT86ZR |
| CitedBy_id | crossref_primary_10_1093_glycob_cwaa110 crossref_primary_10_1158_0008_5472_CAN_18_2888 crossref_primary_10_1038_s41581_019_0129_4 crossref_primary_10_1093_glycob_cwaf023 crossref_primary_10_1016_j_bbcan_2022_188747 crossref_primary_10_3389_fonc_2016_00158 crossref_primary_10_1186_s12943_025_02339_1 crossref_primary_10_1038_oncsis_2017_2 crossref_primary_10_1016_j_sbi_2016_09_013 crossref_primary_10_1186_s12885_018_5129_4 crossref_primary_10_3892_mco_2025_2832 crossref_primary_10_3389_fmolb_2022_962908 crossref_primary_10_3390_cancers13164128 crossref_primary_10_1186_s12885_021_08110_1 crossref_primary_10_1038_s41388_018_0366_1 crossref_primary_10_3390_ijms18050998 crossref_primary_10_7717_peerj_12081 crossref_primary_10_1002_1873_3468_13541 crossref_primary_10_1016_j_gene_2021_145689 crossref_primary_10_3389_fimmu_2025_1585647 crossref_primary_10_1089_omi_2019_0149 crossref_primary_10_1186_s13148_023_01564_z crossref_primary_10_3390_cancers11101598 crossref_primary_10_1016_j_aca_2019_11_012 crossref_primary_10_3390_biom11020247 crossref_primary_10_1016_j_jbc_2023_103051 crossref_primary_10_1186_s13148_018_0507_y crossref_primary_10_31083_j_fbl2810271 crossref_primary_10_1177_1176935117747259 crossref_primary_10_3390_cancers14092128 crossref_primary_10_1186_s12885_020_07675_7 crossref_primary_10_1007_s11010_018_3478_6 crossref_primary_10_1152_physrev_00034_2024 crossref_primary_10_3389_fcell_2020_00490 crossref_primary_10_1002_ctm2_678 crossref_primary_10_1371_journal_pone_0195812 crossref_primary_10_1007_s10719_023_10137_4 crossref_primary_10_3390_biom6020025 crossref_primary_10_1002_1873_3468_12685 crossref_primary_10_1038_s41598_023_30862_y crossref_primary_10_1002_hep4_1032 |
| Cites_doi | 10.1038/bjc.2014.429 10.1074/jbc.M309159200 10.1038/73163 10.1016/j.gpb.2014.09.004 10.1021/pr400861m 10.1016/j.yexcr.2006.05.022 10.1093/clinchem/46.6.795 10.1371/journal.pone.0033191 10.1016/j.bbagen.2013.08.017 10.1158/0008-5472.CAN-10-2607 10.3233/CBM-2012-0239 10.1371/journal.pgen.1001256 10.1371/journal.pone.0054672 10.1016/S0016-5085(03)00268-3 10.1373/clinchem.2009.136333 10.1016/S0304-4165(99)00165-8 10.1158/0008-5472.CAN-09-3911 10.1073/pnas.1107385108 10.1017/S1462399409001033 10.3390/proteomes2010001 10.1053/j.gastro.2008.03.031 10.1038/nri2417 10.4049/jimmunol.180.5.3158 10.1074/jbc.M011100200 10.1021/pr101034t 10.1158/1541-7786.MCR-07-0344 10.1016/j.jhep.2008.12.010 10.1038/nature08021 10.1016/S0168-8278(96)80203-0 10.1074/jbc.M109.031120 10.1186/1471-2407-14-815 10.1093/bioinformatics/btu786 10.4161/epi.6.11.17977 10.1158/1055-9965.EPI-11-1183 10.1007/s13148-011-0039-1 10.1038/nrc3982 10.1093/nar/30.1.207 10.1155/2013/954060 10.1158/1940-6207.CAPR-12-0056 10.1128/MCB.00204-09 10.1038/sj.jid.5700539 10.25011/cim.v34i3.15188 10.1074/mcp.M110.002717 10.1038/sj.onc.1202124 10.1073/pnas.0909862107 10.18632/oncotarget.1652 10.1074/mcp.M113.037085 10.1186/s13148-015-0089-x 10.1016/j.molmed.2012.02.001 10.1126/science.286.5439.531 10.4161/epi.23062 10.1074/jbc.M111.337642 10.1093/carcin/bgt208 10.1038/ni1442 10.1093/glycob/cwq051 10.1007/s10549-004-3137-3 10.1016/j.jaut.2014.12.002 10.1186/1471-2407-14-901 10.1093/gerona/glt190 10.1053/j.gastro.2011.12.039 10.1093/hmg/ddt420 10.1038/ncomms1309 10.1200/JCO.2012.48.5516 10.1146/annurev-pathol-012414-040438 10.3892/ijo.2015.2818 10.1128/MCB.23.16.5908-5918.2003 10.1126/science.1439808 10.1373/clinchem.2012.192328 10.1016/j.molonc.2009.12.001 10.1016/j.bbagen.2012.10.021 10.1038/nm1627 10.1074/jbc.M112.367565 10.1038/nrm3383 10.1016/j.bbagen.2011.12.007 10.4161/epi.26346 10.1038/ncomms4365 10.1126/science.291.5512.2364 10.1038/300274a0 10.1074/jbc.M112.370064 10.1016/j.prp.2009.11.006 10.1002/gcc.20577 10.1002/ijc.28658 10.1093/glycob/cws108 10.1093/glycob/cwr179 10.1038/sj.embor.7400705 10.1158/0008-5472.CAN-05-4610 |
| ContentType | Journal Article |
| Copyright | 2016 Elsevier B.V. Copyright © 2016 Elsevier B.V. All rights reserved. |
| Copyright_xml | – notice: 2016 Elsevier B.V. – notice: Copyright © 2016 Elsevier B.V. All rights reserved. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 7S9 L.6 |
| DOI | 10.1016/j.bbagen.2016.01.002 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic AGRICOLA AGRICOLA - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic AGRICOLA AGRICOLA - Academic |
| DatabaseTitleList | MEDLINE AGRICOLA MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Chemistry Biology Medicine |
| EISSN | 1872-8006 |
| EndPage | 1785 |
| ExternalDocumentID | 26794090 10_1016_j_bbagen_2016_01_002 S0304416516000039 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | --- --K --M .~1 0R~ 1B1 1RT 1~. 1~5 23N 3O- 4.4 457 4G. 53G 5GY 5RE 5VS 7-5 71M 8P~ 9JM AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AAXUO ABEFU ABFNM ABGSF ABMAC ABUDA ABXDB ABYKQ ACDAQ ACIUM ACRLP ADBBV ADEZE ADMUD ADUVX AEBSH AEHWI AEKER AFKWA AFTJW AFXIZ AGHFR AGRDE AGUBO AGYEJ AHHHB AIEXJ AIKHN AITUG AJBFU AJOXV ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC CS3 DOVZS EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HLW HVGLF HZ~ IHE J1W KOM LX3 M41 MO0 N9A O-L O9- OAUVE OHT OZT P-8 P-9 PC. Q38 R2- ROL RPZ SBG SCC SDF SDG SDP SES SEW SPCBC SSU SSZ T5K UQL WH7 WUQ XJT XPP ~G- 9DU AAHBH AATTM AAXKI AAYWO AAYXX ABWVN ACLOT ACRPL ACVFH ADCNI ADNMO AEIPS AEUPX AFJKZ AFPUW AGQPQ AIGII AIIUN AKBMS AKRWK AKYEP ANKPU APXCP CITATION EFKBS ~HD -~X .55 .GJ AAYJJ ABJNI AFFNX AI. CGR CUY CVF ECM EIF F5P H~9 K-O MVM NPM RIG TWZ UHS VH1 X7M Y6R YYP ZE2 ZGI ~KM 7X8 7S9 L.6 |
| ID | FETCH-LOGICAL-c395t-33aefb7ad8994605e64d7a287ed492f0390ccd68dd076acdb64a2763fdf29c053 |
| ISICitedReferencesCount | 46 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000379274800019&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0304-4165 0006-3002 |
| IngestDate | Sat Sep 27 23:07:31 EDT 2025 Thu Oct 02 07:16:08 EDT 2025 Mon Jul 21 06:00:54 EDT 2025 Tue Nov 18 20:51:51 EST 2025 Sat Nov 29 01:38:02 EST 2025 Fri Feb 23 02:32:42 EST 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 8 |
| Keywords | DNA methylation Epigenetics Protein glycosylation Gene expression Cancer |
| Language | English |
| License | Copyright © 2016 Elsevier B.V. All rights reserved. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c395t-33aefb7ad8994605e64d7a287ed492f0390ccd68dd076acdb64a2763fdf29c053 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| PMID | 26794090 |
| PQID | 1797235082 |
| PQPubID | 23479 |
| PageCount | 10 |
| ParticipantIDs | proquest_miscellaneous_1825435459 proquest_miscellaneous_1797235082 pubmed_primary_26794090 crossref_citationtrail_10_1016_j_bbagen_2016_01_002 crossref_primary_10_1016_j_bbagen_2016_01_002 elsevier_sciencedirect_doi_10_1016_j_bbagen_2016_01_002 |
| PublicationCentury | 2000 |
| PublicationDate | August 2016 2016-08-00 2016-Aug 20160801 |
| PublicationDateYYYYMMDD | 2016-08-01 |
| PublicationDate_xml | – month: 08 year: 2016 text: August 2016 |
| PublicationDecade | 2010 |
| PublicationPlace | Netherlands |
| PublicationPlace_xml | – name: Netherlands |
| PublicationTitle | Biochimica et biophysica acta |
| PublicationTitleAlternate | Biochim Biophys Acta |
| PublicationYear | 2016 |
| Publisher | Elsevier B.V |
| Publisher_xml | – name: Elsevier B.V |
| References | Granovsky, Fata, Pawling, Muller, Khokha, Dennis (bb0310) 2000; 6 Pau Ni, Zakaria, Muhammad, Abdullah, Ibrahim, Aina Emran, Hisham Abdullah, Syed Hussain (bb0180) 2010; 206 Mitoma, Bao, Petryanik, Schaerli, Gauguet, Yu, Kawashima, Saito, Ohtsubo, Marth, Khoo, von Andrian, Lowe, Fukuda (bb0020) 2007; 8 Vojta, Zoldos (bb0280) 2013; 2013 Lee, Matthews, Lim, Swanier, Wells, Pierce (bb0345) 2012; 287 Pinho, Oliveira, Cabral, Carvalho, Huntsman, Gartner, Seruca, Reis, Oliveira (bb0355) 2012; 7 Maverakis, Kim, Shimoda, Gershwin, Patel, Wilken, Raychaudhuri, Ruhaak, Lebrilla (bb0045) 2015; 57 Anugraham, Jacob, Nixdorf, Everest-Dass, Heinzelmann-Schwarz, Packer (bb0105) 2014; 13 Tellez, McCarty, Ruiz, Bar-Eli (bb0445) 2003; 278 Marzese, Scolyer, Huynh, Huang, Hirose, Chong, Kiyohara, Wang, Kawas, Donovan, Hata, Wilmott, Murali, Buckland, Shivalingam, Thompson, Morton, Kelly, Hoon (bb0145) 2014; 23 Kim, Ahn, Song, Kang, Lee, Jeon, Kim, Yoo, Ko (bb0315) 2012; 287 Berois, Gattolliat, Barrios, Capandeguy, Douc-Rasy, Valteau-Couanet, Benard, Osinaga (bb0380) 2013; 59 Scotto, Narayan, Nandula, Arias-Pulido, Subramaniyam, Schneider, Kaufmann, Wright, Pothuri, Mansukhani, Murty (bb0200) 2008; 47 Shi, Marconett, Duan, Hyland, Li, Wang, Wheeler, Zhou, Campan, Lee, Huang, Zhou, Triche, Amundadottir, Warner, Hutchinson, Chen, Chung, Pesatori, Consonni, Bertazzi, Bergen, Freedman, Siegmund, Berman, Borok, Chatterjee, Tucker, Caporaso, Chanock, Laird-Offringa, Landi (bb0155) 2014; 5 Zhou, Chen, Wang, Zhang, Zhao (bb0335) 2011; 34 Marth, Grewal (bb0015) 2008; 8 Horvat, Muzinic, Barisic, Bosnar, Zoldos (bb0115) 2012; 1820 Mizuno, Kitada, Nakai, Sarai (bb0210) 2009; 2 Lauc, Vojta, Zoldos (bb0035) 2014; 1840 Horvat, Dezeljin, Redzic, Barisic, Herak Bosnar, Lauc, Zoldos (bb0110) 2013; 8 Wang (bb0420) 2005; 1 Sandoval, Mendez-Gonzalez, Nadal, Chen, Carmona, Sayols, Moran, Heyn, Vizoso, Gomez, Sanchez-Cespedes, Assenov, Muller, Bock, Taron, Mora, Muscarella, Liloglou, Davies, Pollan, Pajares, Torre, Montuenga, Brambilla, Field, Roz, Lo Iacono, Scagliotti, Rosell, Beer, Esteller (bb0160) 2013; 31 Clarke, Madden, Doolan, Aherne, Joyce, O'Driscoll, Gallagher, Hennessy, Moriarty, Crown, Kennedy, Clynes (bb0190) 2013; 34 Mehta, Norton, Liang, Comunale, Wang, Rodemich-Betesh, Koszycki, Noda, Miyoshi, Block (bb0225) 2012; 21 Kagan, Henke, Cabal-Manzano, Stoica, Nguyen, Wellstein, Riegel (bb0460) 2003; 63 Tsuboi, Hatakeyama, Ohyama, Fukuda (bb0070) 2012; 18 Suzuki, Nozawa, Kawaguchi, Abe (bb0400) 2002; 20 de Leoz, Young, An, Kronewitter, Kim, Miyamoto, Borowsky, Chew, Lebrilla (bb0075) 2011; 10 Park, Krishnan, Zhu, Wong, Lee, Troyanskaya (bb0215) 2015; 31 Bos, Zhang, Nadal, Shu, Gomis, Nguyen, Minn, van de Vijver, Gerald, Foekens, Massague (bb0405) 2009; 459 Li, Li, Wu, Li, Yu, Gen, Zhang (bb0320) 2008; 180 Chen, Zhang, Fregien, Pierce (bb0305) 1998; 17 Tellez, Davis, Prieto, Gershenwald, Johnson, McCarty, Bar-Eli (bb0450) 2006; 127 Lasky (bb0010) 1992; 258 Koslowski, Türeci, Biesterfeld, Seitz, Huber, Sahin (bb0455) 2009; 284 Stone, Ismail, Lee, Luu, Ramirez, Haslam, Ho, Dell, Fukuda, Marth (bb0370) 2009; 29 Abbott, Troupe, Lee, Pierce (bb0340) 2006; 312 Durand, Seta (bb0090) 2000; 46 Arnold, Saldova, Galligan, Murphy, Mimura-Kimura, Telford, Godwin, Rudd (bb0260) 2011; 10 Kristic, Vuckovic, Menni, Klaric, Keser, Beceheli, Pucic-Bakovic, Novokmet, Mangino, Thaqi, Rudan, Novokmet, Sarac, Missoni, Kolcic, Polasek, Rudan, Campbell, Hayward, Aulchenko, Valdes, Wilson, Gornik, Primorac, Zoldos, Spector, Lauc (bb0120) 2014; 69 Kroes, He, Emmett, Nilsson, Leach, Amster, Marshall, Moskal (bb0410) 2010; 107 He, Fan, Kapoor, Ingram, Rybak, Austin, Dickhout, Cutz, Scholey, Tang (bb0440) 2011; 2 Lauc, Essafi, Huffman, Hayward, Knezevic, Kattla, Polasek, Gornik, Vitart, Abrahams, Pucic, Novokmet, Redzic, Campbell, Wild, Borovecki, Wang, Kolcic, Zgaga, Gyllensten, Wilson, Wright, Hastie, Campbell, Rudd, Rudan (bb0480) 2010; 6 Rho, Lampe (bb0095) 2014; 2 Saldova, Dempsey, Perez-Garay, Marino, Watson, Blanco-Fernandez, Struwe, Harvey, Madden, Peracaula, McCann, Rudd (bb0125) 2011; 6 Wagner, Punnoose, Januario, Lawrence, Pitti, Lancaster, Lee, von Goetz, Yee, Totpal, Huw, Katta, Cavet, Hymowitz, Amler, Ashkenazi (bb0365) 2007; 13 Fleischer, Frigessi, Johnson, Edvardsen, Touleimat, Klajic, Riis, Haakensen, Warnberg, Naume, Helland, Borresen-Dale, Tost, Christensen, Kristensen (bb0140) 2014; 15 Roessler, Jia, Budhu, Forgues, Ye, Lee, Thorgeirsson, Sun, Tang, Qin, Wang (bb0165) 2010; 70 Roessler, Long, Budhu, Chen, Zhao, Ji, Walker, Jia, Ye, Qin, Tang, He, Hunter, Thorgeirsson, Meltzer, Wang (bb0170) 2012; 142 Shimodaira, Nakayama, Nakamura, Hasebe, Katsuyama, Fukuda (bb0285) 1997; 57 Takamaru, Yamamoto, Suzuki, Nojima, Maruyama, Yamano, Yoshikawa, Kimura, Harada, Ashida, Suzuki, Yamamoto, Kai, Tokino, Sugai, Imai, Toyota, Shinomura (bb0385) 2012; 5 Horvat, Zoldos, Lauc (bb0055) 2011; 2 Potapenko, Haakensen, Luders, Helland, Bukholm, Sorlie, Kristensen, Lingjaerde, Borresen-Dale (bb0330) 2010; 4 Wang, Bachvarova, Morin, Plante, Gregoire, Renaud, Sebastianelli, Bachvarov (bb0390) 2014; 5 Laurent-puig, Plomteux, Bluteau, Zinzindohoué, Jeannot, Dahan, Kartheuser, Chapusot, Cugnenc, Zucman-rossi (bb0470) 2003; 124 Suzuki, Abe, Hashimoto (bb0395) 2015; 46 Farkas, Milutin-Gasperov, Grce, Nilsson (bb0150) 2013; 8 Zahnow (bb0465) 2009; 11 Tuupanen, Hanninen, Kondelin, von Nandelstadh, Cajuso, Gylfe, Katainen, Tanskanen, Ristolainen, Bohm, Mecklin, Jarvinen, Renkonen-Sinisalo, Andersen, Taipale, Taipale, Vahteristo, Lehti, Pitkanen, Aaltonen (bb0375) 2014; 111 Golub, Slonim, Tamayo, Huard, Gaasenbeek, Mesirov, Coller, Loh, Downing, Caligiuri, Bloomfield, Lander (bb0220) 1999; 286 Kawamura, Toyota, Kawashima, Hagiwara, Suzuki, Imai, Shinomura, Tokino, Kannagi, Dohi (bb0425) 2008; 135 Dennis, Waller, Timpl, Schirrmacher (bb0295) 1982; 300 Sethi, Thaysen-Andersen, Smith, Baker, Packer, Hancock, Fanayan (bb0435) 2014; 13 Schuetz, Bonin, Clare, Nieselt, Sotlar, Walter, Fehm, Solomayer, Riess, Wallwiener, Kurek, Neubauer (bb0185) 2006; 66 Pinho, Figueiredo, Cabral, Carvalho, Dourado, Magalhaes, Gartner, Mendonfa, Isaji, Gu, Carneiro, Seruca, Taniguchi, Reis (bb0350) 2013; 1830 Antony, Rose, Heidenreich, Knuchel, Gaisa, Dahl (bb0430) 2014; 14 Peng, Wan, Li, Liu, Li, Tang (bb0250) 2012; 287 Drake, Cho, Li, Prakobphol, Johansen, Anderson, Regnier, Gibson, Fisher (bb0085) 2010; 56 Vasseur, Goetz, Alley, Novotny (bb0270) 2012; 22 Edgar, Domrachev, Lash (bb0130) 2002; 30 Zang, Guo, Xing, Zhang, Li, Zhao, Fang, Hu, Kang, Ren, Zhuang, Liu, Wang, Li, Yu, Cheng, Lu (bb0415) 2014; 12 Blomme, Van Steenkiste, Callewaert, Van Vlierberghe (bb0230) 2009; 50 Chen, Huang, Huang, Liao, Su, Wang, Chang, Lin, Yu, Chu, Lai (bb0255) 2014; 135 Ninomiya, Yoshitake, Kiyofumi, Kyosuke, Seitetsu, Hidekazu, Taiki, Masato, Hiroshi (bb0475) 1996; 25 Wang, Cheng, Chen, Chang, Chuang, Kao (bb0175) 2014; 14 Xu, Shen, Hoshida, Subramanian, Ross, Brunet, Wagner, Ramaswamy, Mesirov, Hynes (bb0195) 2008; 6 Nadanaka, Sato, Kitajima, Katagiri, Irie, Yamagata (bb0300) 2001; 276 Apweiler, Hermjakob, Sharon (bb0040) 1999; 1473 National Research Council (U.S.). Committee on Assessing the Importance and Impact of Glycomics and Glycosciences, National Research Council (U.S.). Board on Chemical Sciences and Technology, National Research Council (U.S.). Board on Life Sciences (bb0050) 2012 Julien, Lagadec, Krzewinski-Recchi, Courtand, Le Bourhis, Delannoy (bb0290) 2005; 90 Bartling, Vanhooren, Dewaele, Libert, Hofmann, Haerting, Nuding, Silber, Simm, Chen (bb0265) 2011; 10 Seidenfaden, Krauter, Schertzinger, Gerardy-Schahn, Hildebrandt (bb0065) 2003; 23 Brockhausen (bb0235) 2006; 7 Pangeni, Channathodiyil, Huen, Eagles, Johal, Pasha, Hadjistephanou, Nevell, Davies, Adewumi, Khanom, Samra, Buzatto, Chandrasekaran, Shinawi, Dawson, Ashton, Davis, Brodbelt, Jenkinson, Bieche, Latif, Darling, Warr, Morris (bb0245) 2015; 7 Helenius, Aebi (bb0025) 2001; 291 Liu, Yen, Chen, Chen, Cheng, Juan, Chen, Khoo, Yu, Yang, Hsu, Wong (bb0275) 2011; 108 Knezevic, Gornik, Polasek, Pucic, Redzic, Novokmet, Rudd, Wright, Campbell, Rudan, Lauc (bb0030) 2010; 20 Stowell, Ju, Cummings (bb0060) 2015; 10 Shen, Wang, Zhang, Wu, Kibriya, Jasmine, Ahsan, Wu, Siegel, Remotti, Santella (bb0135) 2013; 8 Huanna, Tao, Xiangfei, Longfei, Yuanyuan, Jianhua, Cuifang, Manjing, Wenjing, Shaochuan, Feifei, Naikang, Jinchao, Chen (bb0080) 2014 Park, Nishidate, Kijima, Ohashi, Takegawa, Fujikane, Hirata, Nakamura, Katagiri (bb0240) 2010; 70 Liu, Zhang, Chen, Jiang, Zhang, Guo, Liu (bb0325) 2014; 9 R Core Team (bb0205) 2014 Moremen, Tiemeyer, Nairn (bb0005) 2012; 13 Li, Wang, Li, Xu, Shao, Xie, Xie, Kubota, Narimatsu, Zhang (bb0360) 2012; 22 Pinho, Reis (bb0100) 2015; 15 Schuetz (10.1016/j.bbagen.2016.01.002_bb0185) 2006; 66 Pangeni (10.1016/j.bbagen.2016.01.002_bb0245) 2015; 7 Fleischer (10.1016/j.bbagen.2016.01.002_bb0140) 2014; 15 Roessler (10.1016/j.bbagen.2016.01.002_bb0170) 2012; 142 Farkas (10.1016/j.bbagen.2016.01.002_bb0150) 2013; 8 Pinho (10.1016/j.bbagen.2016.01.002_bb0355) 2012; 7 Lasky (10.1016/j.bbagen.2016.01.002_bb0010) 1992; 258 Scotto (10.1016/j.bbagen.2016.01.002_bb0200) 2008; 47 Tsuboi (10.1016/j.bbagen.2016.01.002_bb0070) 2012; 18 Suzuki (10.1016/j.bbagen.2016.01.002_bb0395) 2015; 46 Pinho (10.1016/j.bbagen.2016.01.002_bb0350) 2013; 1830 Sandoval (10.1016/j.bbagen.2016.01.002_bb0160) 2013; 31 Drake (10.1016/j.bbagen.2016.01.002_bb0085) 2010; 56 Stone (10.1016/j.bbagen.2016.01.002_bb0370) 2009; 29 Shimodaira (10.1016/j.bbagen.2016.01.002_bb0285) 1997; 57 Moremen (10.1016/j.bbagen.2016.01.002_bb0005) 2012; 13 Bartling (10.1016/j.bbagen.2016.01.002_bb0265) 2011; 10 Xu (10.1016/j.bbagen.2016.01.002_bb0195) 2008; 6 Antony (10.1016/j.bbagen.2016.01.002_bb0430) 2014; 14 Blomme (10.1016/j.bbagen.2016.01.002_bb0230) 2009; 50 Horvat (10.1016/j.bbagen.2016.01.002_bb0055) 2011; 2 Clarke (10.1016/j.bbagen.2016.01.002_bb0190) 2013; 34 Zang (10.1016/j.bbagen.2016.01.002_bb0415) 2014; 12 Roessler (10.1016/j.bbagen.2016.01.002_bb0165) 2010; 70 Wang (10.1016/j.bbagen.2016.01.002_bb0175) 2014; 14 Durand (10.1016/j.bbagen.2016.01.002_bb0090) 2000; 46 Golub (10.1016/j.bbagen.2016.01.002_bb0220) 1999; 286 Apweiler (10.1016/j.bbagen.2016.01.002_bb0040) 1999; 1473 Marth (10.1016/j.bbagen.2016.01.002_bb0015) 2008; 8 Huanna (10.1016/j.bbagen.2016.01.002_bb0080) 2014 de Leoz (10.1016/j.bbagen.2016.01.002_bb0075) 2011; 10 Anugraham (10.1016/j.bbagen.2016.01.002_bb0105) 2014; 13 Wagner (10.1016/j.bbagen.2016.01.002_bb0365) 2007; 13 Bos (10.1016/j.bbagen.2016.01.002_bb0405) 2009; 459 Horvat (10.1016/j.bbagen.2016.01.002_bb0115) 2012; 1820 Park (10.1016/j.bbagen.2016.01.002_bb0215) 2015; 31 Peng (10.1016/j.bbagen.2016.01.002_bb0250) 2012; 287 Mizuno (10.1016/j.bbagen.2016.01.002_bb0210) 2009; 2 Kagan (10.1016/j.bbagen.2016.01.002_bb0460) 2003; 63 Vasseur (10.1016/j.bbagen.2016.01.002_bb0270) 2012; 22 Zhou (10.1016/j.bbagen.2016.01.002_bb0335) 2011; 34 Julien (10.1016/j.bbagen.2016.01.002_bb0290) 2005; 90 National Research Council (U.S.). Committee on Assessing the Importance and Impact of Glycomics and Glycosciences, National Research Council (U.S.). Board on Chemical Sciences and Technology, National Research Council (U.S.). Board on Life Sciences (10.1016/j.bbagen.2016.01.002_bb0050) 2012 Knezevic (10.1016/j.bbagen.2016.01.002_bb0030) 2010; 20 Suzuki (10.1016/j.bbagen.2016.01.002_bb0400) 2002; 20 Edgar (10.1016/j.bbagen.2016.01.002_bb0130) 2002; 30 Vojta (10.1016/j.bbagen.2016.01.002_bb0280) 2013; 2013 Nadanaka (10.1016/j.bbagen.2016.01.002_bb0300) 2001; 276 Tuupanen (10.1016/j.bbagen.2016.01.002_bb0375) 2014; 111 Dennis (10.1016/j.bbagen.2016.01.002_bb0295) 1982; 300 Takamaru (10.1016/j.bbagen.2016.01.002_bb0385) 2012; 5 Ninomiya (10.1016/j.bbagen.2016.01.002_bb0475) 1996; 25 Kawamura (10.1016/j.bbagen.2016.01.002_bb0425) 2008; 135 Chen (10.1016/j.bbagen.2016.01.002_bb0305) 1998; 17 Tellez (10.1016/j.bbagen.2016.01.002_bb0445) 2003; 278 Seidenfaden (10.1016/j.bbagen.2016.01.002_bb0065) 2003; 23 Brockhausen (10.1016/j.bbagen.2016.01.002_bb0235) 2006; 7 Li (10.1016/j.bbagen.2016.01.002_bb0320) 2008; 180 Saldova (10.1016/j.bbagen.2016.01.002_bb0125) 2011; 6 Helenius (10.1016/j.bbagen.2016.01.002_bb0025) 2001; 291 He (10.1016/j.bbagen.2016.01.002_bb0440) 2011; 2 Maverakis (10.1016/j.bbagen.2016.01.002_bb0045) 2015; 57 Arnold (10.1016/j.bbagen.2016.01.002_bb0260) 2011; 10 Liu (10.1016/j.bbagen.2016.01.002_bb0275) 2011; 108 Wang (10.1016/j.bbagen.2016.01.002_bb0420) 2005; 1 Kim (10.1016/j.bbagen.2016.01.002_bb0315) 2012; 287 Sethi (10.1016/j.bbagen.2016.01.002_bb0435) 2014; 13 Mitoma (10.1016/j.bbagen.2016.01.002_bb0020) 2007; 8 Kristic (10.1016/j.bbagen.2016.01.002_bb0120) 2014; 69 Shi (10.1016/j.bbagen.2016.01.002_bb0155) 2014; 5 Rho (10.1016/j.bbagen.2016.01.002_bb0095) 2014; 2 Chen (10.1016/j.bbagen.2016.01.002_bb0255) 2014; 135 Stowell (10.1016/j.bbagen.2016.01.002_bb0060) 2015; 10 Granovsky (10.1016/j.bbagen.2016.01.002_bb0310) 2000; 6 Wang (10.1016/j.bbagen.2016.01.002_bb0390) 2014; 5 Zahnow (10.1016/j.bbagen.2016.01.002_bb0465) 2009; 11 Berois (10.1016/j.bbagen.2016.01.002_bb0380) 2013; 59 Park (10.1016/j.bbagen.2016.01.002_bb0240) 2010; 70 Laurent-puig (10.1016/j.bbagen.2016.01.002_bb0470) 2003; 124 Lauc (10.1016/j.bbagen.2016.01.002_bb0480) 2010; 6 Pau Ni (10.1016/j.bbagen.2016.01.002_bb0180) 2010; 206 Liu (10.1016/j.bbagen.2016.01.002_bb0325) 2014; 9 Lee (10.1016/j.bbagen.2016.01.002_bb0345) 2012; 287 Li (10.1016/j.bbagen.2016.01.002_bb0360) 2012; 22 Shen (10.1016/j.bbagen.2016.01.002_bb0135) 2013; 8 Lauc (10.1016/j.bbagen.2016.01.002_bb0035) 2014; 1840 Horvat (10.1016/j.bbagen.2016.01.002_bb0110) 2013; 8 R Core Team (10.1016/j.bbagen.2016.01.002_bb0205) 2014 Abbott (10.1016/j.bbagen.2016.01.002_bb0340) 2006; 312 Koslowski (10.1016/j.bbagen.2016.01.002_bb0455) 2009; 284 Tellez (10.1016/j.bbagen.2016.01.002_bb0450) 2006; 127 Potapenko (10.1016/j.bbagen.2016.01.002_bb0330) 2010; 4 Pinho (10.1016/j.bbagen.2016.01.002_bb0100) 2015; 15 Kroes (10.1016/j.bbagen.2016.01.002_bb0410) 2010; 107 Marzese (10.1016/j.bbagen.2016.01.002_bb0145) 2014; 23 Mehta (10.1016/j.bbagen.2016.01.002_bb0225) 2012; 21 |
| References_xml | – volume: 287 start-page: 14301 year: 2012 end-page: 14309 ident: bb0250 article-title: MicroRNA-214 suppresses growth and invasiveness of cervical cancer cells by targeting UDP-N-acetyl-alpha- publication-title: J. Biol. Chem. – volume: 13 start-page: 1070 year: 2007 end-page: 1077 ident: bb0365 article-title: Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL publication-title: Nat. Med. – year: 2012 ident: bb0050 article-title: Transforming Glycoscience: A Roadmap for the Future – volume: 70 start-page: 10202 year: 2010 end-page: 10212 ident: bb0165 article-title: A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients publication-title: Cancer Res. – volume: 286 start-page: 531 year: 1999 end-page: 537 ident: bb0220 article-title: Molecular classification of cancer: class discovery and class prediction by gene expression monitoring publication-title: Science – volume: 135 start-page: 142 year: 2008 end-page: 151 ident: bb0425 article-title: DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer publication-title: Gastroenterology – volume: 23 start-page: 226 year: 2014 end-page: 238 ident: bb0145 article-title: Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis publication-title: Hum. Mol. Genet. – year: 2014 ident: bb0205 article-title: R: A Language and Environment for Statistical Computing – volume: 107 start-page: 12646 year: 2010 end-page: 12651 ident: bb0410 article-title: Overexpression of ST6GalNAcV, a ganglioside-specific alpha2,6-sialyltransferase, inhibits glioma growth in vivo publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 5 start-page: 544 year: 2014 end-page: 560 ident: bb0390 article-title: Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation publication-title: Oncotarget – volume: 1820 start-page: 1412 year: 2012 end-page: 1419 ident: bb0115 article-title: Epigenetic modulation of the HeLa cell membrane N-glycome publication-title: Biochim. Biophys. Acta – volume: 66 start-page: 5278 year: 2006 end-page: 5286 ident: bb0185 article-title: Progression-specific genes identified by expression profiling of matched ductal carcinomas in situ and invasive breast tumors, combining laser capture microdissection and oligonucleotide microarray analysis publication-title: Cancer Res. – volume: 90 start-page: 77 year: 2005 end-page: 84 ident: bb0290 article-title: Stable expression of sialyl-Tn antigen in T47-D cells induces a decrease of cell adhesion and an increase of cell migration publication-title: Breast Cancer Res. Treat. – volume: 14 start-page: 815 year: 2014 ident: bb0175 article-title: Plasmalemmal vesicle associated protein (PLVAP) as a therapeutic target for treatment of hepatocellular carcinoma publication-title: BMC Cancer – volume: 180 start-page: 3158 year: 2008 end-page: 3165 ident: bb0320 article-title: Knockdown of Mgat5 inhibits breast cancer cell growth with activation of CD4 publication-title: J. Immunol. – volume: 14 start-page: 901 year: 2014 ident: bb0430 article-title: Epigenetic inactivation of ST6GAL1 in human bladder cancer publication-title: BMC Cancer – volume: 15 start-page: 435 year: 2014 ident: bb0140 article-title: Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis publication-title: Genome Biol. – volume: 287 start-page: 28526 year: 2012 end-page: 28536 ident: bb0345 article-title: Developmental expression of the neuron-specific N-acetylglucosaminyltransferase Vb (GnT-Vb/IX) and identification of its in vivo glycan products in comparison with those of its paralog, GnT-V publication-title: J. Biol. Chem. – volume: 13 start-page: 448 year: 2012 end-page: 462 ident: bb0005 article-title: Vertebrate protein glycosylation: diversity, synthesis and function publication-title: Nat. Rev. Mol. Cell Biol. – volume: 10 year: 2011 ident: bb0075 article-title: High-mannose glycans are elevated during breast cancer progression publication-title: Mol. Cell. Proteomics – volume: 111 start-page: 1657 year: 2014 end-page: 1662 ident: bb0375 article-title: Identification of 33 candidate oncogenes by screening for base-specific mutations publication-title: Br. J. Cancer – volume: 6 start-page: 306 year: 2000 end-page: 312 ident: bb0310 article-title: Suppression of tumor growth and metastasis in Mgat5-deficient mice publication-title: Nat. Med. – volume: 124 start-page: 1311 year: 2003 end-page: 1314 ident: bb0470 article-title: Frequent mutations of hepatocyte nuclear factor 1 in colorectal cancer with microsatellite instability publication-title: Gastroenterology – volume: 4 start-page: 98 year: 2010 end-page: 118 ident: bb0330 article-title: Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression publication-title: Mol. Oncol. – volume: 7 start-page: 599 year: 2006 end-page: 604 ident: bb0235 article-title: Mucin-type O-glycans in human colon and breast cancer: glycodynamics and functions publication-title: EMBO Rep. – volume: 21 start-page: 925 year: 2012 end-page: 933 ident: bb0225 article-title: Increased levels of tetra-antennary N-linked glycan but not core fucosylation are associated with hepatocellular carcinoma tissue: a publication of the American Association for Cancer Research, cosponsored by the Americn Society of Preventive Oncology publication-title: Cancer Epidemiol. Biomarkers Prev. – volume: 2 start-page: 18 year: 2009 ident: bb0210 article-title: PrognoScan: a new database for meta-analysis of the prognostic value of genes publication-title: BMC Med. Genet. – volume: 31 start-page: 1093 year: 2015 end-page: 1101 ident: bb0215 article-title: Tissue-aware data integration approach for the inference of pathway interactions in metazoan organisms publication-title: Bioinformatics – volume: 12 start-page: 276 year: 2014 end-page: 283 ident: bb0415 article-title: Identification of differentially-expressed genes in intestinal gastric cancer by microarray analysis publication-title: Genomics Proteomics Bioinformatics – volume: 284 start-page: 28607 year: 2009 end-page: 28615 ident: bb0455 article-title: Selective activation of trophoblast-specific PLAC1 in breast cancer by CCAAT/enhancer-binding protein β (C/EBPβ) isoform 2 publication-title: J. Biol. Chem. – volume: 1 start-page: 73 year: 2005 end-page: 81 ident: bb0420 article-title: Altered glycosylation in cancer: sialic acids and sialyltransferases publication-title: J. Cancer Mol. – volume: 69 start-page: 779 year: 2014 end-page: 789 ident: bb0120 article-title: Glycans are a novel biomarker of chronological and biological ages publication-title: J. Gerontol. A Biol. Sci. Med. Sci. – volume: 300 start-page: 274 year: 1982 end-page: 276 ident: bb0295 article-title: Surface sialic acid reduces attachment of metastatic tumour cells to collagen type IV and fibronectin publication-title: Nature – volume: 22 start-page: 1684 year: 2012 end-page: 1708 ident: bb0270 article-title: Smoking and lung cancer-induced changes in N-glycosylation of blood serum proteins publication-title: Glycobiology – volume: 34 start-page: E155 year: 2011 end-page: E162 ident: bb0335 article-title: Knockdown of Mgat5 inhibits CD133 publication-title: Clin. Invest. Med. – volume: 2 start-page: 307 year: 2011 ident: bb0440 article-title: Alpha-mannosidase 2C1 attenuates PTEN function in prostate cancer cells publication-title: Nat. Commun. – volume: 15 start-page: 540 year: 2015 end-page: 555 ident: bb0100 article-title: Glycosylation in cancer: mechanisms and clinical implications publication-title: Nat. Rev. Cancer – volume: 135 start-page: 117 year: 2014 end-page: 127 ident: bb0255 article-title: Methylomics analysis identifies epigenetically silenced genes and implies an activation of beta-catenin signaling in cervical cancer publication-title: Int. J. Cancer J. Int. du Cancer – volume: 2 start-page: 1 year: 2014 ident: bb0095 article-title: High-throughput analysis of plasma hybrid markers for early detection of cancers publication-title: Proteomes – volume: 11 start-page: e12-e12 year: 2009 ident: bb0465 article-title: CCAAT/enhancer-binding protein β: its role in breast cancer and associations with receptor tyrosine kinases publication-title: Expert Rev. Mol. Med. – volume: 18 start-page: 224 year: 2012 end-page: 232 ident: bb0070 article-title: Two opposing roles of O-glycans in tumor metastasis publication-title: Trends Mol. Med. – volume: 23 start-page: 5908 year: 2003 end-page: 5918 ident: bb0065 article-title: Polysialic acid directs tumor cell growth by controlling heterophilic neural cell adhesion molecule interactions publication-title: Mol. Cell. Biol. – year: 2014 ident: bb0080 article-title: GALNT14 mediates tumor invasion and migration in breast cancer cell MCF-7 publication-title: Mol. Carcinog. – volume: 278 start-page: 46632 year: 2003 end-page: 46642 ident: bb0445 article-title: Loss of activator protein-2α results in overexpression of protease-activated receptor-1 and correlates with the malignant phenotype of human melanoma publication-title: J. Biol. Chem. – volume: 70 start-page: 2759 year: 2010 end-page: 2769 ident: bb0240 article-title: Critical roles of mucin 1 glycosylation by transactivated polypeptide N-acetylgalactosaminyltransferase 6 in mammary carcinogenesis publication-title: Cancer Res. – volume: 47 start-page: 755 year: 2008 end-page: 765 ident: bb0200 article-title: Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: potential role in progression publication-title: Genes Chromosom. Cancer – volume: 108 start-page: 11332 year: 2011 end-page: 11337 ident: bb0275 article-title: Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 20 start-page: 1005 year: 2002 end-page: 1011 ident: bb0400 article-title: UDP-GlcNAc2-epimerase regulates cell surface sialylation and cell adhesion to extracellular matrix in Burkitt's lymphoma publication-title: Int. J. Oncol. – volume: 25 start-page: 445 year: 1996 end-page: 453 ident: bb0475 article-title: Expression ratio of hepatocyte nuclear factor-1 to variant hepatocyte nuclear factor-1 in differentiation of hepatocellular carcinoma and hepatoblastoma publication-title: J. Hepatol. – volume: 258 start-page: 964 year: 1992 end-page: 969 ident: bb0010 article-title: Selectins: interpreters of cell-specific carbohydrate information during inflammation publication-title: Science – volume: 10 start-page: 145 year: 2011 end-page: 154 ident: bb0265 article-title: Altered desialylated plasma N-glycan profile in patients with non-small cell lung carcinoma publication-title: Cancer Biomark. – volume: 5 start-page: 3365 year: 2014 ident: bb0155 article-title: Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue publication-title: Nature Commun. – volume: 276 start-page: 33657 year: 2001 end-page: 33664 ident: bb0300 article-title: Occurrence of oligosialic acids on integrin alpha 5 subunit and their involvement in cell adhesion to fibronectin publication-title: J. Biol. Chem. – volume: 127 start-page: 387 year: 2006 end-page: 393 ident: bb0450 article-title: Quantitative analysis of melanocytic tissue array reveals inverse correlation between activator protein-2[alpha] and protease-activated receptor-1 expression during melanoma progression publication-title: J. Investig. Dermatol. – volume: 10 start-page: 473 year: 2015 end-page: 510 ident: bb0060 article-title: Protein glycosylation in cancer publication-title: Annu. Rev. Pathol. – volume: 50 start-page: 592 year: 2009 end-page: 603 ident: bb0230 article-title: Alteration of protein glycosylation in liver diseases publication-title: J. Hepatol. – volume: 1830 start-page: 2690 year: 2013 end-page: 2700 ident: bb0350 article-title: E-cadherin and adherens-junctions stability in gastric carcinoma: functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V publication-title: Biochim. Biophys. Acta – volume: 287 start-page: 32467 year: 2012 end-page: 32478 ident: bb0315 article-title: Overexpression and beta-1,6-N-acetylglucosaminylation-initiated aberrant glycosylation of TIMP-1: a “double whammy” strategy in colon cancer progression publication-title: J. Biol. Chem. – volume: 7 year: 2012 ident: bb0355 article-title: Loss and recovery of Mgat3 and GnT-III mediated E-cadherin N-glycosylation is a mechanism involved in epithelial–mesenchymal–epithelial transitions publication-title: PLoS One – volume: 17 start-page: 2087 year: 1998 end-page: 2093 ident: bb0305 article-title: The her-2/neu oncogene stimulates the transcription of N-acetylglucosaminyltransferase V and expression of its cell surface oligosaccharide products publication-title: Oncogene – volume: 9 year: 2014 ident: bb0325 article-title: The transcriptional profiling of glycogenes associated with hepatocellular carcinoma metastasis publication-title: PLoS One – volume: 8 start-page: 874 year: 2008 end-page: 887 ident: bb0015 article-title: Mammalian glycosylation in immunity publication-title: Nat. Rev. Immunol. – volume: 8 start-page: 1213 year: 2013 end-page: 1225 ident: bb0150 article-title: Genome-wide DNA methylation assay reveals novel candidate biomarker genes in cervical cancer publication-title: Epigenetics – volume: 34 start-page: 2300 year: 2013 end-page: 2308 ident: bb0190 article-title: Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis publication-title: Carcinogenesis – volume: 6 year: 2010 ident: bb0480 article-title: Genomics meets glycomics—the first GWAS study of human N-glycome identifies HNF1alpha as a master regulator of plasma protein fucosylation publication-title: PLoS Genet. – volume: 63 start-page: 1696 year: 2003 end-page: 1705 ident: bb0460 article-title: Complex regulation of the fibroblast growth factor-binding protein in MDA-MB-468 breast cancer cells by CCAAT/enhancer-binding protein β publication-title: Cancer Res. – volume: 20 start-page: 959 year: 2010 end-page: 969 ident: bb0030 article-title: Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans publication-title: Glycobiology – volume: 1840 start-page: 65 year: 2014 end-page: 70 ident: bb0035 article-title: Epigenetic regulation of glycosylation is the quantum mechanics of biology publication-title: Biochim. Biophys. Acta – volume: 56 start-page: 223 year: 2010 end-page: 236 ident: bb0085 article-title: Sweetening the pot: adding glycosylation to the biomarker discovery equation publication-title: Clin. Chem. – volume: 8 year: 2013 ident: bb0110 article-title: Reversibility of membrane N-glycome of HeLa cells upon treatment with epigenetic inhibitors publication-title: PLoS One – volume: 1473 start-page: 4 year: 1999 end-page: 8 ident: bb0040 article-title: On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT database publication-title: Biochim. Biophys. Acta – volume: 6 start-page: 1362 year: 2011 end-page: 1372 ident: bb0125 article-title: 5-AZA-2′-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer publication-title: Epigenetics – volume: 8 start-page: 34 year: 2013 end-page: 43 ident: bb0135 article-title: Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips publication-title: Epigenetics – volume: 57 start-page: 5201 year: 1997 end-page: 5206 ident: bb0285 article-title: Carcinoma-associated expression of core 2 beta-1,6-N-acetylglucosaminyltransferase gene in human colorectal cancer: role of O-glycans in tumor progression publication-title: Cancer Res. – volume: 5 start-page: 1203 year: 2012 end-page: 1212 ident: bb0385 article-title: Aberrant methylation of RASGRF1 is associated with an epigenetic field defect and increased risk of gastric cancer publication-title: Cancer Prev. Res. – volume: 291 start-page: 2364 year: 2001 end-page: 2369 ident: bb0025 article-title: Intracellular functions of N-linked glycans publication-title: Science – volume: 46 start-page: 795 year: 2000 end-page: 805 ident: bb0090 article-title: Protein glycosylation and diseases: blood and urinary oligosaccharides as markers for diagnosis and therapeutic monitoring publication-title: Clin. Chem. – volume: 31 start-page: 4140 year: 2013 end-page: 4147 ident: bb0160 article-title: A prognostic DNA methylation signature for stage I non-small-cell lung cancer publication-title: J. Clin. Oncol. Off. J. Am. Soc. Clin. Oncol. – volume: 29 start-page: 3770 year: 2009 end-page: 3782 ident: bb0370 article-title: Glycosyltransferase function in core 2-type protein O glycosylation publication-title: Mol. Cell. Biol. – volume: 59 start-page: 225 year: 2013 end-page: 233 ident: bb0380 article-title: GALNT9 gene expression is a prognostic marker in neuroblastoma patients publication-title: Clin. Chem. – volume: 46 start-page: 973 year: 2015 end-page: 980 ident: bb0395 article-title: Sialylation by beta-galactoside alpha-2,6-sialyltransferase and N-glycans regulate cell adhesion and invasion in human anaplastic large cell lymphoma publication-title: Int. J. Oncol. – volume: 13 start-page: 2213 year: 2014 end-page: 2232 ident: bb0105 article-title: Specific glycosylation of membrane proteins in epithelial ovarian cancer cell lines: glycan structures reflect gene expression and DNA methylation status publication-title: Mol. Cell. Proteomics – volume: 2 start-page: 425 year: 2011 end-page: 432 ident: bb0055 article-title: Evolutional and clinical implications of the epigenetic regulation of protein glycosylation publication-title: Clin. Epigenetics – volume: 206 start-page: 223 year: 2010 end-page: 228 ident: bb0180 article-title: Gene expression patterns distinguish breast carcinomas from normal breast tissues: the Malaysian context publication-title: Pathol. Res. Pract. – volume: 2013 start-page: 954060 year: 2013 ident: bb0280 article-title: Adaptation or malignant transformation: the two faces of epigenetically mediated response to stress publication-title: BioMed Res. Int. – volume: 459 start-page: 1005 year: 2009 end-page: 1009 ident: bb0405 article-title: Genes that mediate breast cancer metastasis to the brain publication-title: Nature – volume: 142 start-page: 957 year: 2012 end-page: 966 ident: bb0170 article-title: Integrative genomic identification of genes on 8p associated with hepatocellular carcinoma progression and patient survival publication-title: Gastroenterology – volume: 7 start-page: 57 year: 2015 ident: bb0245 article-title: The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain publication-title: Clin. Epigenetics – volume: 312 start-page: 2837 year: 2006 end-page: 2850 ident: bb0340 article-title: Integrin-dependent neuroblastoma cell adhesion and migration on laminin is regulated by expression levels of two enzymes in the O-mannosyl-linked glycosylation pathway, PomGnT1 and GnT-Vb publication-title: Exp. Cell Res. – volume: 30 start-page: 207 year: 2002 end-page: 210 ident: bb0130 article-title: Gene expression omnibus: NCBI gene expression and hybridization array data repository publication-title: Nucleic Acids Res. – volume: 10 start-page: 1755 year: 2011 end-page: 1764 ident: bb0260 article-title: Novel glycan biomarkers for the detection of lung cancer publication-title: J. Proteome Res. – volume: 8 start-page: 409 year: 2007 end-page: 418 ident: bb0020 article-title: Critical functions of N-glycans in publication-title: Nat. Immunol. – volume: 57 start-page: 1 year: 2015 end-page: 13 ident: bb0045 article-title: Glycans in the immune system and the altered glycan theory of autoimmunity: a critical review publication-title: J. Autoimmun. – volume: 6 start-page: 760 year: 2008 end-page: 769 ident: bb0195 article-title: Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases publication-title: Mol. Cancer Res. – volume: 22 start-page: 602 year: 2012 end-page: 615 ident: bb0360 article-title: Characterization of ppGalNAc-T18, a member of the vertebrate-specific Y subfamily of UDP-N-acetyl-alpha- publication-title: Glycobiology – volume: 13 start-page: 277 year: 2014 end-page: 288 ident: bb0435 article-title: Comparative N-glycan profiling of colorectal cancer cell lines reveals unique bisecting GlcNAc and alpha-2,3-linked sialic acid determinants are associated with membrane proteins of the more metastatic/aggressive cell lines publication-title: J. Proteome Res. – volume: 111 start-page: 1657 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0375 article-title: Identification of 33 candidate oncogenes by screening for base-specific mutations publication-title: Br. J. Cancer doi: 10.1038/bjc.2014.429 – volume: 278 start-page: 46632 year: 2003 ident: 10.1016/j.bbagen.2016.01.002_bb0445 article-title: Loss of activator protein-2α results in overexpression of protease-activated receptor-1 and correlates with the malignant phenotype of human melanoma publication-title: J. Biol. Chem. doi: 10.1074/jbc.M309159200 – volume: 6 start-page: 306 year: 2000 ident: 10.1016/j.bbagen.2016.01.002_bb0310 article-title: Suppression of tumor growth and metastasis in Mgat5-deficient mice publication-title: Nat. Med. doi: 10.1038/73163 – volume: 12 start-page: 276 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0415 article-title: Identification of differentially-expressed genes in intestinal gastric cancer by microarray analysis publication-title: Genomics Proteomics Bioinformatics doi: 10.1016/j.gpb.2014.09.004 – volume: 13 start-page: 277 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0435 article-title: Comparative N-glycan profiling of colorectal cancer cell lines reveals unique bisecting GlcNAc and alpha-2,3-linked sialic acid determinants are associated with membrane proteins of the more metastatic/aggressive cell lines publication-title: J. Proteome Res. doi: 10.1021/pr400861m – volume: 312 start-page: 2837 year: 2006 ident: 10.1016/j.bbagen.2016.01.002_bb0340 article-title: Integrin-dependent neuroblastoma cell adhesion and migration on laminin is regulated by expression levels of two enzymes in the O-mannosyl-linked glycosylation pathway, PomGnT1 and GnT-Vb publication-title: Exp. Cell Res. doi: 10.1016/j.yexcr.2006.05.022 – volume: 46 start-page: 795 year: 2000 ident: 10.1016/j.bbagen.2016.01.002_bb0090 article-title: Protein glycosylation and diseases: blood and urinary oligosaccharides as markers for diagnosis and therapeutic monitoring publication-title: Clin. Chem. doi: 10.1093/clinchem/46.6.795 – volume: 7 year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0355 article-title: Loss and recovery of Mgat3 and GnT-III mediated E-cadherin N-glycosylation is a mechanism involved in epithelial–mesenchymal–epithelial transitions publication-title: PLoS One doi: 10.1371/journal.pone.0033191 – volume: 2 start-page: 18 year: 2009 ident: 10.1016/j.bbagen.2016.01.002_bb0210 article-title: PrognoScan: a new database for meta-analysis of the prognostic value of genes publication-title: BMC Med. Genet. – volume: 1840 start-page: 65 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0035 article-title: Epigenetic regulation of glycosylation is the quantum mechanics of biology publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbagen.2013.08.017 – volume: 70 start-page: 10202 year: 2010 ident: 10.1016/j.bbagen.2016.01.002_bb0165 article-title: A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-10-2607 – volume: 10 start-page: 145 year: 2011 ident: 10.1016/j.bbagen.2016.01.002_bb0265 article-title: Altered desialylated plasma N-glycan profile in patients with non-small cell lung carcinoma publication-title: Cancer Biomark. doi: 10.3233/CBM-2012-0239 – volume: 6 year: 2010 ident: 10.1016/j.bbagen.2016.01.002_bb0480 article-title: Genomics meets glycomics—the first GWAS study of human N-glycome identifies HNF1alpha as a master regulator of plasma protein fucosylation publication-title: PLoS Genet. doi: 10.1371/journal.pgen.1001256 – volume: 8 year: 2013 ident: 10.1016/j.bbagen.2016.01.002_bb0110 article-title: Reversibility of membrane N-glycome of HeLa cells upon treatment with epigenetic inhibitors publication-title: PLoS One doi: 10.1371/journal.pone.0054672 – volume: 124 start-page: 1311 year: 2003 ident: 10.1016/j.bbagen.2016.01.002_bb0470 article-title: Frequent mutations of hepatocyte nuclear factor 1 in colorectal cancer with microsatellite instability publication-title: Gastroenterology doi: 10.1016/S0016-5085(03)00268-3 – volume: 56 start-page: 223 year: 2010 ident: 10.1016/j.bbagen.2016.01.002_bb0085 article-title: Sweetening the pot: adding glycosylation to the biomarker discovery equation publication-title: Clin. Chem. doi: 10.1373/clinchem.2009.136333 – volume: 1473 start-page: 4 year: 1999 ident: 10.1016/j.bbagen.2016.01.002_bb0040 article-title: On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT database publication-title: Biochim. Biophys. Acta doi: 10.1016/S0304-4165(99)00165-8 – volume: 70 start-page: 2759 year: 2010 ident: 10.1016/j.bbagen.2016.01.002_bb0240 article-title: Critical roles of mucin 1 glycosylation by transactivated polypeptide N-acetylgalactosaminyltransferase 6 in mammary carcinogenesis publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-09-3911 – volume: 108 start-page: 11332 year: 2011 ident: 10.1016/j.bbagen.2016.01.002_bb0275 article-title: Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.1107385108 – volume: 11 start-page: e12-e12 year: 2009 ident: 10.1016/j.bbagen.2016.01.002_bb0465 article-title: CCAAT/enhancer-binding protein β: its role in breast cancer and associations with receptor tyrosine kinases publication-title: Expert Rev. Mol. Med. doi: 10.1017/S1462399409001033 – volume: 2 start-page: 1 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0095 article-title: High-throughput analysis of plasma hybrid markers for early detection of cancers publication-title: Proteomes doi: 10.3390/proteomes2010001 – year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0205 – volume: 135 start-page: 142 year: 2008 ident: 10.1016/j.bbagen.2016.01.002_bb0425 article-title: DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer publication-title: Gastroenterology doi: 10.1053/j.gastro.2008.03.031 – volume: 8 start-page: 874 year: 2008 ident: 10.1016/j.bbagen.2016.01.002_bb0015 article-title: Mammalian glycosylation in immunity publication-title: Nat. Rev. Immunol. doi: 10.1038/nri2417 – volume: 180 start-page: 3158 year: 2008 ident: 10.1016/j.bbagen.2016.01.002_bb0320 article-title: Knockdown of Mgat5 inhibits breast cancer cell growth with activation of CD4+ T cells and macrophages publication-title: J. Immunol. doi: 10.4049/jimmunol.180.5.3158 – volume: 276 start-page: 33657 year: 2001 ident: 10.1016/j.bbagen.2016.01.002_bb0300 article-title: Occurrence of oligosialic acids on integrin alpha 5 subunit and their involvement in cell adhesion to fibronectin publication-title: J. Biol. Chem. doi: 10.1074/jbc.M011100200 – volume: 10 start-page: 1755 year: 2011 ident: 10.1016/j.bbagen.2016.01.002_bb0260 article-title: Novel glycan biomarkers for the detection of lung cancer publication-title: J. Proteome Res. doi: 10.1021/pr101034t – volume: 1 start-page: 73 year: 2005 ident: 10.1016/j.bbagen.2016.01.002_bb0420 article-title: Altered glycosylation in cancer: sialic acids and sialyltransferases publication-title: J. Cancer Mol. – year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0080 article-title: GALNT14 mediates tumor invasion and migration in breast cancer cell MCF-7 publication-title: Mol. Carcinog. – volume: 6 start-page: 760 year: 2008 ident: 10.1016/j.bbagen.2016.01.002_bb0195 article-title: Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases publication-title: Mol. Cancer Res. doi: 10.1158/1541-7786.MCR-07-0344 – volume: 50 start-page: 592 year: 2009 ident: 10.1016/j.bbagen.2016.01.002_bb0230 article-title: Alteration of protein glycosylation in liver diseases publication-title: J. Hepatol. doi: 10.1016/j.jhep.2008.12.010 – volume: 459 start-page: 1005 year: 2009 ident: 10.1016/j.bbagen.2016.01.002_bb0405 article-title: Genes that mediate breast cancer metastasis to the brain publication-title: Nature doi: 10.1038/nature08021 – volume: 25 start-page: 445 year: 1996 ident: 10.1016/j.bbagen.2016.01.002_bb0475 article-title: Expression ratio of hepatocyte nuclear factor-1 to variant hepatocyte nuclear factor-1 in differentiation of hepatocellular carcinoma and hepatoblastoma publication-title: J. Hepatol. doi: 10.1016/S0168-8278(96)80203-0 – volume: 284 start-page: 28607 year: 2009 ident: 10.1016/j.bbagen.2016.01.002_bb0455 article-title: Selective activation of trophoblast-specific PLAC1 in breast cancer by CCAAT/enhancer-binding protein β (C/EBPβ) isoform 2 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M109.031120 – volume: 14 start-page: 815 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0175 article-title: Plasmalemmal vesicle associated protein (PLVAP) as a therapeutic target for treatment of hepatocellular carcinoma publication-title: BMC Cancer doi: 10.1186/1471-2407-14-815 – volume: 31 start-page: 1093 year: 2015 ident: 10.1016/j.bbagen.2016.01.002_bb0215 article-title: Tissue-aware data integration approach for the inference of pathway interactions in metazoan organisms publication-title: Bioinformatics doi: 10.1093/bioinformatics/btu786 – volume: 6 start-page: 1362 year: 2011 ident: 10.1016/j.bbagen.2016.01.002_bb0125 article-title: 5-AZA-2′-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer publication-title: Epigenetics doi: 10.4161/epi.6.11.17977 – volume: 21 start-page: 925 year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0225 article-title: Increased levels of tetra-antennary N-linked glycan but not core fucosylation are associated with hepatocellular carcinoma tissue: a publication of the American Association for Cancer Research, cosponsored by the Americn Society of Preventive Oncology publication-title: Cancer Epidemiol. Biomarkers Prev. doi: 10.1158/1055-9965.EPI-11-1183 – volume: 2 start-page: 425 year: 2011 ident: 10.1016/j.bbagen.2016.01.002_bb0055 article-title: Evolutional and clinical implications of the epigenetic regulation of protein glycosylation publication-title: Clin. Epigenetics doi: 10.1007/s13148-011-0039-1 – volume: 15 start-page: 540 year: 2015 ident: 10.1016/j.bbagen.2016.01.002_bb0100 article-title: Glycosylation in cancer: mechanisms and clinical implications publication-title: Nat. Rev. Cancer doi: 10.1038/nrc3982 – volume: 30 start-page: 207 year: 2002 ident: 10.1016/j.bbagen.2016.01.002_bb0130 article-title: Gene expression omnibus: NCBI gene expression and hybridization array data repository publication-title: Nucleic Acids Res. doi: 10.1093/nar/30.1.207 – volume: 57 start-page: 5201 year: 1997 ident: 10.1016/j.bbagen.2016.01.002_bb0285 article-title: Carcinoma-associated expression of core 2 beta-1,6-N-acetylglucosaminyltransferase gene in human colorectal cancer: role of O-glycans in tumor progression publication-title: Cancer Res. – volume: 2013 start-page: 954060 year: 2013 ident: 10.1016/j.bbagen.2016.01.002_bb0280 article-title: Adaptation or malignant transformation: the two faces of epigenetically mediated response to stress publication-title: BioMed Res. Int. doi: 10.1155/2013/954060 – volume: 5 start-page: 1203 year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0385 article-title: Aberrant methylation of RASGRF1 is associated with an epigenetic field defect and increased risk of gastric cancer publication-title: Cancer Prev. Res. doi: 10.1158/1940-6207.CAPR-12-0056 – volume: 29 start-page: 3770 year: 2009 ident: 10.1016/j.bbagen.2016.01.002_bb0370 article-title: Glycosyltransferase function in core 2-type protein O glycosylation publication-title: Mol. Cell. Biol. doi: 10.1128/MCB.00204-09 – volume: 127 start-page: 387 year: 2006 ident: 10.1016/j.bbagen.2016.01.002_bb0450 article-title: Quantitative analysis of melanocytic tissue array reveals inverse correlation between activator protein-2[alpha] and protease-activated receptor-1 expression during melanoma progression publication-title: J. Investig. Dermatol. doi: 10.1038/sj.jid.5700539 – volume: 34 start-page: E155 year: 2011 ident: 10.1016/j.bbagen.2016.01.002_bb0335 article-title: Knockdown of Mgat5 inhibits CD133+ human pulmonary adenocarcinoma cell growth in vitro and in vivo publication-title: Clin. Invest. Med. doi: 10.25011/cim.v34i3.15188 – volume: 10 year: 2011 ident: 10.1016/j.bbagen.2016.01.002_bb0075 article-title: High-mannose glycans are elevated during breast cancer progression publication-title: Mol. Cell. Proteomics doi: 10.1074/mcp.M110.002717 – volume: 17 start-page: 2087 year: 1998 ident: 10.1016/j.bbagen.2016.01.002_bb0305 article-title: The her-2/neu oncogene stimulates the transcription of N-acetylglucosaminyltransferase V and expression of its cell surface oligosaccharide products publication-title: Oncogene doi: 10.1038/sj.onc.1202124 – volume: 107 start-page: 12646 year: 2010 ident: 10.1016/j.bbagen.2016.01.002_bb0410 article-title: Overexpression of ST6GalNAcV, a ganglioside-specific alpha2,6-sialyltransferase, inhibits glioma growth in vivo publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0909862107 – volume: 5 start-page: 544 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0390 article-title: Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation publication-title: Oncotarget doi: 10.18632/oncotarget.1652 – volume: 63 start-page: 1696 year: 2003 ident: 10.1016/j.bbagen.2016.01.002_bb0460 article-title: Complex regulation of the fibroblast growth factor-binding protein in MDA-MB-468 breast cancer cells by CCAAT/enhancer-binding protein β publication-title: Cancer Res. – volume: 13 start-page: 2213 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0105 article-title: Specific glycosylation of membrane proteins in epithelial ovarian cancer cell lines: glycan structures reflect gene expression and DNA methylation status publication-title: Mol. Cell. Proteomics doi: 10.1074/mcp.M113.037085 – volume: 7 start-page: 57 year: 2015 ident: 10.1016/j.bbagen.2016.01.002_bb0245 article-title: The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain publication-title: Clin. Epigenetics doi: 10.1186/s13148-015-0089-x – volume: 18 start-page: 224 year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0070 article-title: Two opposing roles of O-glycans in tumor metastasis publication-title: Trends Mol. Med. doi: 10.1016/j.molmed.2012.02.001 – volume: 286 start-page: 531 year: 1999 ident: 10.1016/j.bbagen.2016.01.002_bb0220 article-title: Molecular classification of cancer: class discovery and class prediction by gene expression monitoring publication-title: Science doi: 10.1126/science.286.5439.531 – volume: 8 start-page: 34 year: 2013 ident: 10.1016/j.bbagen.2016.01.002_bb0135 article-title: Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips publication-title: Epigenetics doi: 10.4161/epi.23062 – volume: 287 start-page: 14301 year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0250 article-title: MicroRNA-214 suppresses growth and invasiveness of cervical cancer cells by targeting UDP-N-acetyl-alpha-d-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M111.337642 – volume: 34 start-page: 2300 year: 2013 ident: 10.1016/j.bbagen.2016.01.002_bb0190 article-title: Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis publication-title: Carcinogenesis doi: 10.1093/carcin/bgt208 – volume: 8 start-page: 409 year: 2007 ident: 10.1016/j.bbagen.2016.01.002_bb0020 article-title: Critical functions of N-glycans in l-selectin-mediated lymphocyte homing and recruitment publication-title: Nat. Immunol. doi: 10.1038/ni1442 – volume: 20 start-page: 959 year: 2010 ident: 10.1016/j.bbagen.2016.01.002_bb0030 article-title: Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans publication-title: Glycobiology doi: 10.1093/glycob/cwq051 – volume: 9 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0325 article-title: The transcriptional profiling of glycogenes associated with hepatocellular carcinoma metastasis publication-title: PLoS One – volume: 90 start-page: 77 year: 2005 ident: 10.1016/j.bbagen.2016.01.002_bb0290 article-title: Stable expression of sialyl-Tn antigen in T47-D cells induces a decrease of cell adhesion and an increase of cell migration publication-title: Breast Cancer Res. Treat. doi: 10.1007/s10549-004-3137-3 – volume: 57 start-page: 1 year: 2015 ident: 10.1016/j.bbagen.2016.01.002_bb0045 article-title: Glycans in the immune system and the altered glycan theory of autoimmunity: a critical review publication-title: J. Autoimmun. doi: 10.1016/j.jaut.2014.12.002 – volume: 15 start-page: 435 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0140 article-title: Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis publication-title: Genome Biol. – volume: 14 start-page: 901 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0430 article-title: Epigenetic inactivation of ST6GAL1 in human bladder cancer publication-title: BMC Cancer doi: 10.1186/1471-2407-14-901 – volume: 69 start-page: 779 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0120 article-title: Glycans are a novel biomarker of chronological and biological ages publication-title: J. Gerontol. A Biol. Sci. Med. Sci. doi: 10.1093/gerona/glt190 – volume: 142 start-page: 957 year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0170 article-title: Integrative genomic identification of genes on 8p associated with hepatocellular carcinoma progression and patient survival publication-title: Gastroenterology doi: 10.1053/j.gastro.2011.12.039 – volume: 23 start-page: 226 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0145 article-title: Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/ddt420 – volume: 2 start-page: 307 year: 2011 ident: 10.1016/j.bbagen.2016.01.002_bb0440 article-title: Alpha-mannosidase 2C1 attenuates PTEN function in prostate cancer cells publication-title: Nat. Commun. doi: 10.1038/ncomms1309 – volume: 31 start-page: 4140 year: 2013 ident: 10.1016/j.bbagen.2016.01.002_bb0160 article-title: A prognostic DNA methylation signature for stage I non-small-cell lung cancer publication-title: J. Clin. Oncol. Off. J. Am. Soc. Clin. Oncol. doi: 10.1200/JCO.2012.48.5516 – volume: 10 start-page: 473 year: 2015 ident: 10.1016/j.bbagen.2016.01.002_bb0060 article-title: Protein glycosylation in cancer publication-title: Annu. Rev. Pathol. doi: 10.1146/annurev-pathol-012414-040438 – volume: 46 start-page: 973 year: 2015 ident: 10.1016/j.bbagen.2016.01.002_bb0395 article-title: Sialylation by beta-galactoside alpha-2,6-sialyltransferase and N-glycans regulate cell adhesion and invasion in human anaplastic large cell lymphoma publication-title: Int. J. Oncol. doi: 10.3892/ijo.2015.2818 – volume: 23 start-page: 5908 year: 2003 ident: 10.1016/j.bbagen.2016.01.002_bb0065 article-title: Polysialic acid directs tumor cell growth by controlling heterophilic neural cell adhesion molecule interactions publication-title: Mol. Cell. Biol. doi: 10.1128/MCB.23.16.5908-5918.2003 – volume: 258 start-page: 964 year: 1992 ident: 10.1016/j.bbagen.2016.01.002_bb0010 article-title: Selectins: interpreters of cell-specific carbohydrate information during inflammation publication-title: Science doi: 10.1126/science.1439808 – volume: 59 start-page: 225 year: 2013 ident: 10.1016/j.bbagen.2016.01.002_bb0380 article-title: GALNT9 gene expression is a prognostic marker in neuroblastoma patients publication-title: Clin. Chem. doi: 10.1373/clinchem.2012.192328 – volume: 4 start-page: 98 year: 2010 ident: 10.1016/j.bbagen.2016.01.002_bb0330 article-title: Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression publication-title: Mol. Oncol. doi: 10.1016/j.molonc.2009.12.001 – volume: 1830 start-page: 2690 year: 2013 ident: 10.1016/j.bbagen.2016.01.002_bb0350 article-title: E-cadherin and adherens-junctions stability in gastric carcinoma: functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbagen.2012.10.021 – volume: 13 start-page: 1070 year: 2007 ident: 10.1016/j.bbagen.2016.01.002_bb0365 article-title: Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL publication-title: Nat. Med. doi: 10.1038/nm1627 – volume: 287 start-page: 28526 year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0345 article-title: Developmental expression of the neuron-specific N-acetylglucosaminyltransferase Vb (GnT-Vb/IX) and identification of its in vivo glycan products in comparison with those of its paralog, GnT-V publication-title: J. Biol. Chem. doi: 10.1074/jbc.M112.367565 – volume: 13 start-page: 448 year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0005 article-title: Vertebrate protein glycosylation: diversity, synthesis and function publication-title: Nat. Rev. Mol. Cell Biol. doi: 10.1038/nrm3383 – year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0050 – volume: 1820 start-page: 1412 year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0115 article-title: Epigenetic modulation of the HeLa cell membrane N-glycome publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbagen.2011.12.007 – volume: 8 start-page: 1213 year: 2013 ident: 10.1016/j.bbagen.2016.01.002_bb0150 article-title: Genome-wide DNA methylation assay reveals novel candidate biomarker genes in cervical cancer publication-title: Epigenetics doi: 10.4161/epi.26346 – volume: 5 start-page: 3365 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0155 article-title: Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue publication-title: Nature Commun. doi: 10.1038/ncomms4365 – volume: 291 start-page: 2364 year: 2001 ident: 10.1016/j.bbagen.2016.01.002_bb0025 article-title: Intracellular functions of N-linked glycans publication-title: Science doi: 10.1126/science.291.5512.2364 – volume: 300 start-page: 274 year: 1982 ident: 10.1016/j.bbagen.2016.01.002_bb0295 article-title: Surface sialic acid reduces attachment of metastatic tumour cells to collagen type IV and fibronectin publication-title: Nature doi: 10.1038/300274a0 – volume: 287 start-page: 32467 year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0315 article-title: Overexpression and beta-1,6-N-acetylglucosaminylation-initiated aberrant glycosylation of TIMP-1: a “double whammy” strategy in colon cancer progression publication-title: J. Biol. Chem. doi: 10.1074/jbc.M112.370064 – volume: 206 start-page: 223 year: 2010 ident: 10.1016/j.bbagen.2016.01.002_bb0180 article-title: Gene expression patterns distinguish breast carcinomas from normal breast tissues: the Malaysian context publication-title: Pathol. Res. Pract. doi: 10.1016/j.prp.2009.11.006 – volume: 47 start-page: 755 year: 2008 ident: 10.1016/j.bbagen.2016.01.002_bb0200 article-title: Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: potential role in progression publication-title: Genes Chromosom. Cancer doi: 10.1002/gcc.20577 – volume: 135 start-page: 117 year: 2014 ident: 10.1016/j.bbagen.2016.01.002_bb0255 article-title: Methylomics analysis identifies epigenetically silenced genes and implies an activation of beta-catenin signaling in cervical cancer publication-title: Int. J. Cancer J. Int. du Cancer doi: 10.1002/ijc.28658 – volume: 22 start-page: 1684 year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0270 article-title: Smoking and lung cancer-induced changes in N-glycosylation of blood serum proteins publication-title: Glycobiology doi: 10.1093/glycob/cws108 – volume: 22 start-page: 602 year: 2012 ident: 10.1016/j.bbagen.2016.01.002_bb0360 article-title: Characterization of ppGalNAc-T18, a member of the vertebrate-specific Y subfamily of UDP-N-acetyl-alpha-d-galactosamine:polypeptide N-acetylgalactosaminyltransferases publication-title: Glycobiology doi: 10.1093/glycob/cwr179 – volume: 20 start-page: 1005 year: 2002 ident: 10.1016/j.bbagen.2016.01.002_bb0400 article-title: UDP-GlcNAc2-epimerase regulates cell surface sialylation and cell adhesion to extracellular matrix in Burkitt's lymphoma publication-title: Int. J. Oncol. – volume: 7 start-page: 599 year: 2006 ident: 10.1016/j.bbagen.2016.01.002_bb0235 article-title: Mucin-type O-glycans in human colon and breast cancer: glycodynamics and functions publication-title: EMBO Rep. doi: 10.1038/sj.embor.7400705 – volume: 66 start-page: 5278 year: 2006 ident: 10.1016/j.bbagen.2016.01.002_bb0185 article-title: Progression-specific genes identified by expression profiling of matched ductal carcinomas in situ and invasive breast tumors, combining laser capture microdissection and oligonucleotide microarray analysis publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-05-4610 |
| SSID | ssj0000595 ssj0025309 |
| Score | 2.3883548 |
| Snippet | Most eukaryotic proteins are modified by covalent addition of glycan molecules that considerably influence their function. Aberrant glycosylation is profoundly... |
| SourceID | proquest pubmed crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 1776 |
| SubjectTerms | biosynthesis brain Cancer data collection Databases, Genetic DNA Methylation DNA, Neoplasm - genetics DNA, Neoplasm - metabolism Epigenesis, Genetic Epigenetics Female Gene expression Gene Expression Regulation, Enzymologic Gene Expression Regulation, Neoplastic genes glycosylation Humans lung neoplasms lymph nodes Male mannosidases medicine melanoma metastasis Neoplasm Proteins - biosynthesis Neoplasm Proteins - genetics Neoplasms - enzymology Neoplasms - genetics polysaccharides prognosis Promoter Regions, Genetic Protein glycosylation proteins transferases |
| Title | Glyco-genes change expression in cancer through aberrant methylation |
| URI | https://dx.doi.org/10.1016/j.bbagen.2016.01.002 https://www.ncbi.nlm.nih.gov/pubmed/26794090 https://www.proquest.com/docview/1797235082 https://www.proquest.com/docview/1825435459 |
| Volume | 1860 |
| WOSCitedRecordID | wos000379274800019&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVESC databaseName: Elsevier SD Freedom Collection Journals 2021 customDbUrl: eissn: 1872-8006 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000595 issn: 0304-4165 databaseCode: AIEXJ dateStart: 19950118 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1bb9MwFLZKB4IXBINBuUxBgqcqU5yb48fSFRiCag8DVbxEju1A2iiZepm238Sf5NhOnIppG3vgJUoT27LznfocHx-fD6G3Ac2TJBbY5TmOXJglsZuBXez6vsQ8jjDY0EKTTZDpNJnN6HGv97s9C3NWkqpKzs_p6X-FGp4B2Oro7C3gto3CA7gH0OEKsMP1n4D_WF7w2v2p5rDmWK9K42_CXXVYI1dALy1DD8vkEhTWWpNJX5QdUu1Wb1HzX4XKKjCU62FW1MYZwlQaDnbQ5q0erjaZculYE_17PTeG6aiUi5X2V1hvDlNh3ePo3ftJMddljhS1s_UM1NrCPVwYT8KXzcK--lGXolY1R1gH6EJvm5eN4wLHNmzOHtjyQpAOQxXRTcaGXqARu2RrbsWExFt6GhPD9XNJBxh3xPwgy6CYSnGLY52Z1fM7ndfu8_-lCm2AYhv7Nk9NK6lqJfVwqhOX7vgkokkf7YyOJrPPneKPNMmPHVd7UlOHE17uzVWW0FUrHW3xnDxCD5ulijMyIvYY9WS1i-4Z8tKLXXR_3HIFPkGHW0LnGKFzOqFzisoxQuc0Que0QudsCd1T9O3D5GT8yW34OVwe0GjtBgGTeUaYgDW72l6XcSgIgyW4FCH1cy-gHuciToTwSMy4yOKQ-aDPcpH7lMPsv4f6VV3J58gJw4gTmDciqvyQMU44U3dhlvhUEMEGKGi_Vcqb5PWKQ6VMr0NqgFxb69Qkb7mhPGlhSBsD1BiWKcjWDTXftKil8OnVphurZL1ZpaDwiB_AMui6MspNA8ON6AA9M5Db_voxaEyPei9uOZaX6EH3p3uF-uvlRr5Gd_nZulgt99EdMkv2GwGGX9Pjr38Aw-jIZQ |
| linkProvider | Elsevier |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Glyco-genes+change+expression+in+cancer+through+aberrant+methylation&rft.jtitle=Biochimica+et+biophysica+acta.+General+subjects&rft.au=Vojta%2C+Aleksandar&rft.au=Samar%C5%BEija%2C+Ivana&rft.au=Bo%C4%8Dkor%2C+Luka&rft.au=Zoldo%C5%A1%2C+Vlatka&rft.date=2016-08-01&rft.issn=0304-4165&rft.volume=1860&rft.issue=8&rft.spage=1776&rft.epage=1785&rft_id=info:doi/10.1016%2Fj.bbagen.2016.01.002&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_bbagen_2016_01_002 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0304-4165&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0304-4165&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0304-4165&client=summon |