Structure-based mechanism of preferential complex formation by apoptosis signal-regulating kinases

Apoptosis signal-regulating kinases (ASK1, ASK2, and ASK3) are activators of the p38 and c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase (MAPK) pathways. ASK1-3 form oligomeric complexes known as ASK signalosomes that initiate signaling cascades in response to diverse stress stimuli....

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Bibliographic Details

Published in:	Science signaling Vol. 13; no. 622
Main Authors:	Trevelyan, Sarah J, Brewster, Jodi L, Burgess, Abigail E, Crowther, Jennifer M, Cadell, Antonia L, Parker, Benjamin L, Croucher, David R, Dobson, Renwick C J, Murphy, James M, Mace, Peter D
Format:	Journal Article
Language:	English
Published:	United States 10.03.2020
ISSN:	1937-9145, 1937-9145
Online Access:	Get more information
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