Isolation and molecular characterization of Fikirini rhabdovirus, a novel virus from a Kenyan bat

Zoonotic and vector-borne pathogens have comprised a significant component of emerging human infections in recent decades, and bats are increasingly recognized as reservoirs for many of these disease agents. To identify novel pathogens associated with bats, we screened tissues of bats collected in K...

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Veröffentlicht in:Journal of general virology Jg. 94; H. Pt 11; S. 2393
Hauptverfasser: Kading, Rebekah C, Gilbert, Amy T, Mossel, Eric C, Crabtree, Mary B, Kuzmin, Ivan V, Niezgoda, Michael, Agwanda, Bernard, Markotter, Wanda, Weil, M Ryan, Montgomery, Joel M, Rupprecht, Charles E, Miller, Barry R
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England 01.11.2013
Schlagworte:
Animals
Chiroptera - virology
Disease Reservoirs - virology
High-Throughput Nucleotide Sequencing - methods
Kenya
Liver - virology
Molecular Sequence Data
Phylogeny
Rhabdoviridae - classification
Rhabdoviridae - genetics
Rhabdoviridae - isolation & purification
Rhabdoviridae Infections - veterinary
Rhabdoviridae Infections - virology
RNA, Viral - genetics
Sequence Analysis, DNA - methods
Kenya
ISSN:1465-2099, 1465-2099
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Beschreibung
Zusammenfassung:Zoonotic and vector-borne pathogens have comprised a significant component of emerging human infections in recent decades, and bats are increasingly recognized as reservoirs for many of these disease agents. To identify novel pathogens associated with bats, we screened tissues of bats collected in Kenya. Virus isolates were identified by next generation sequencing of viral nucleic acid preparations from the infected cell culture supernatant and characterized. Here we report the identification of Fikirini rhabdovirus, a novel rhabdovirus isolated from a bat, Hipposideros vittatus, captured along the Kenyan coast.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1465-2099
1465-2099
DOI:10.1099/vir.0.053983-0