Assessment of Plasma-Endogenous Opioid Neuropeptide Levels and Psychometric Properties of Non-Suicidal Self-Injury in Adolescents

Non-suicidal self-injury (NSSI) is one of the most common mental health problems and growing public-health issues, coupled with a significant population-level burden among adolescents in both developed and developing countries. We aimed to assess the role of endogenous opioid system-emotion regulati...

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Published in:	Archives of suicide research Vol. 27; no. 2; pp. 749 - 768
Main Authors:	Cakin Memik, Nursu, Hunc, Fatih, Kalayci, Seyma, Demir, Necmettin, Senturk, Elif, Yildiz Gundogdu, Ozlem, Ozlen Dillioglugil, Meltem
Format:	Journal Article
Language:	English
Published:	England Routledge 03.04.2023 Taylor & Francis Ltd
Subjects:	Adolescent Adolescents Analgesics, Opioid beta-endorphin brief symptom inventory Child Developing countries Emotional Regulation Emotions Endogenous Health problems Humans Injuries inventory of statements about self-injury LDCs Measurement Measures Mental depression Mental disorders Mental health Narcotics Neuropeptides non-suicidal self-injury Opioids Plasma Plasma levels Property Psychometrics Public health Quantitative psychology Research subjects Self destructive behavior Self evaluation Self injury Self-Injurious Behavior - psychology Sociodemographics Suicidal behavior Suicide Teenagers beta-endorphin inventory of statements about self-injury Adolescents non-suicidal self-injury brief symptom inventory
ISSN:	1381-1118, 1543-6136, 1543-6136
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Abstract	Non-suicidal self-injury (NSSI) is one of the most common mental health problems and growing public-health issues, coupled with a significant population-level burden among adolescents in both developed and developing countries. We aimed to assess the role of endogenous opioid system-emotion regulation circuitry in NSSI through measurement of plasma beta-endorphin (β-EP), met-enkephalin (MENK) levels, and determination of psychometric features of Turkish adolescent subjects. In this research, we measured plasma β-EP and MENK levels of 49 adolescents with NSSI and 39 control subjects without NSSI between the ages of 12-18 years. All adolescent subjects were observed in the outpatient clinic, and their clinical and sociodemographic characteristics were examined. All subjects were assessed using the Brief Symptom Inventory (BSI) and Inventory of Statements About Self Injury (ISAS). Plasma β-EP levels were statistically lower in adolescents with NSSI than control group, whereas there was no statistically significant difference in MENK levels. β-EP levels showed a negative correlation with depression severity. The data obtained from BSI and ISAS were not found to be associated with both β-EP and MENK levels, while subscale scores exhibited versatile correlations. Our findings supported the salient role of β-EP in NSSI behavior. Also, decreased plasma β-EP could be assessed as a reliable indicator for NSSI. However, it is possible that measurement of basal plasma levels of neuropeptides might also bring many confounders and could cause bias. Therefore, repeated measurements of plasma-endogenous opioid neuropeptides in a time-dependent manner-concomitant to engage of NSSI behavior-might give more reliable results.
AbstractList	Non-suicidal self-injury (NSSI) is one of the most common mental health problems and growing public-health issues, coupled with a significant population-level burden among adolescents in both developed and developing countries. We aimed to assess the role of endogenous opioid system-emotion regulation circuitry in NSSI through measurement of plasma beta-endorphin (β-EP), met-enkephalin (MENK) levels, and determination of psychometric features of Turkish adolescent subjects.OBJECTIVENon-suicidal self-injury (NSSI) is one of the most common mental health problems and growing public-health issues, coupled with a significant population-level burden among adolescents in both developed and developing countries. We aimed to assess the role of endogenous opioid system-emotion regulation circuitry in NSSI through measurement of plasma beta-endorphin (β-EP), met-enkephalin (MENK) levels, and determination of psychometric features of Turkish adolescent subjects.In this research, we measured plasma β-EP and MENK levels of 49 adolescents with NSSI and 39 control subjects without NSSI between the ages of 12-18 years. All adolescent subjects were observed in the outpatient clinic, and their clinical and sociodemographic characteristics were examined. All subjects were assessed using the Brief Symptom Inventory (BSI) and Inventory of Statements About Self Injury (ISAS).METHODIn this research, we measured plasma β-EP and MENK levels of 49 adolescents with NSSI and 39 control subjects without NSSI between the ages of 12-18 years. All adolescent subjects were observed in the outpatient clinic, and their clinical and sociodemographic characteristics were examined. All subjects were assessed using the Brief Symptom Inventory (BSI) and Inventory of Statements About Self Injury (ISAS).Plasma β-EP levels were statistically lower in adolescents with NSSI than control group, whereas there was no statistically significant difference in MENK levels. β-EP levels showed a negative correlation with depression severity. The data obtained from BSI and ISAS were not found to be associated with both β-EP and MENK levels, while subscale scores exhibited versatile correlations.RESULTSPlasma β-EP levels were statistically lower in adolescents with NSSI than control group, whereas there was no statistically significant difference in MENK levels. β-EP levels showed a negative correlation with depression severity. The data obtained from BSI and ISAS were not found to be associated with both β-EP and MENK levels, while subscale scores exhibited versatile correlations.Our findings supported the salient role of β-EP in NSSI behavior. Also, decreased plasma β-EP could be assessed as a reliable indicator for NSSI. However, it is possible that measurement of basal plasma levels of neuropeptides might also bring many confounders and could cause bias. Therefore, repeated measurements of plasma-endogenous opioid neuropeptides in a time-dependent manner-concomitant to engage of NSSI behavior-might give more reliable results.CONCLUSIONOur findings supported the salient role of β-EP in NSSI behavior. Also, decreased plasma β-EP could be assessed as a reliable indicator for NSSI. However, it is possible that measurement of basal plasma levels of neuropeptides might also bring many confounders and could cause bias. Therefore, repeated measurements of plasma-endogenous opioid neuropeptides in a time-dependent manner-concomitant to engage of NSSI behavior-might give more reliable results. Non-suicidal self-injury (NSSI) is one of the most common mental health problems and growing public-health issues, coupled with a significant population-level burden among adolescents in both developed and developing countries. We aimed to assess the role of endogenous opioid system-emotion regulation circuitry in NSSI through measurement of plasma beta-endorphin (β-EP), met-enkephalin (MENK) levels, and determination of psychometric features of Turkish adolescent subjects. In this research, we measured plasma β-EP and MENK levels of 49 adolescents with NSSI and 39 control subjects without NSSI between the ages of 12-18 years. All adolescent subjects were observed in the outpatient clinic, and their clinical and sociodemographic characteristics were examined. All subjects were assessed using the Brief Symptom Inventory (BSI) and Inventory of Statements About Self Injury (ISAS). Plasma β-EP levels were statistically lower in adolescents with NSSI than control group, whereas there was no statistically significant difference in MENK levels. β-EP levels showed a negative correlation with depression severity. The data obtained from BSI and ISAS were not found to be associated with both β-EP and MENK levels, while subscale scores exhibited versatile correlations. Our findings supported the salient role of β-EP in NSSI behavior. Also, decreased plasma β-EP could be assessed as a reliable indicator for NSSI. However, it is possible that measurement of basal plasma levels of neuropeptides might also bring many confounders and could cause bias. Therefore, repeated measurements of plasma-endogenous opioid neuropeptides in a time-dependent manner-concomitant to engage of NSSI behavior-might give more reliable results. ObjectiveNon-suicidal self-injury (NSSI) is one of the most common mental health problems and growing public-health issues, coupled with a significant population-level burden among adolescents in both developed and developing countries. We aimed to assess the role of endogenous opioid system–emotion regulation circuitry in NSSI through measurement of plasma beta-endorphin (β-EP), met-enkephalin (MENK) levels, and determination of psychometric features of Turkish adolescent subjects.MethodIn this research, we measured plasma β-EP and MENK levels of 49 adolescents with NSSI and 39 control subjects without NSSI between the ages of 12–18 years. All adolescent subjects were observed in the outpatient clinic, and their clinical and sociodemographic characteristics were examined. All subjects were assessed using the Brief Symptom Inventory (BSI) and Inventory of Statements About Self Injury (ISAS).ResultsPlasma β-EP levels were statistically lower in adolescents with NSSI than control group, whereas there was no statistically significant difference in MENK levels. β-EP levels showed a negative correlation with depression severity. The data obtained from BSI and ISAS were not found to be associated with both β-EP and MENK levels, while subscale scores exhibited versatile correlations.ConclusionOur findings supported the salient role of β-EP in NSSI behavior. Also, decreased plasma β-EP could be assessed as a reliable indicator for NSSI. However, it is possible that measurement of basal plasma levels of neuropeptides might also bring many confounders and could cause bias. Therefore, repeated measurements of plasma-endogenous opioid neuropeptides in a time-dependent manner—concomitant to engage of NSSI behavior—might give more reliable results.
Author	Senturk, Elif Ozlen Dillioglugil, Meltem Kalayci, Seyma Demir, Necmettin Hunc, Fatih Yildiz Gundogdu, Ozlem Cakin Memik, Nursu
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Cites_doi	10.1046/j.1440-1819.2003.01088.x 10.1080/16506070701778951 10.1016/S0025-7125(05)70125-5 10.1016/S0140-6736(83)90572-X 10.1080/13811118.2013.748404 10.1016/j.physbeh.2003.08.001 10.1016/j.eatbeh.2005.09.003 10.1016/j.cpr.2006.08.002 10.1007/BF00178514 10.1016/j.jpsychores.2008.10.013 10.1111/j.1460-9568.2006.04744.x 10.1016/j.ab.2018.07.001 10.1111/jcpp.12866 10.1002/1098-2779(200102)7:1<3::AID-MRDD1002>3.0.CO;2- 10.1016/j.jad.2009.10.028 10.1016/j.psychres.2008.06.011 10.1080/15374410801955771 10.1016/j.psychres.2006.05.010 10.1176/appi.books.9780890425596 10.1007/s10964-005-7262-z 10.1007/s00127-015-1060-z 10.1080/13811110701247602 10.1002/mrdd.1410010209 10.1111/sltb.12070 10.1016/0306-3623(88)90137-1 10.5505/kpd.2018.02997 10.1016/j.socscimed.2010.06.034 10.1521/suli.2007.37.6.605 10.17826/cumj.466375 10.1080/13811110802324748 10.1016/j.canlet.2017.03.022 10.1016/j.jad.2020.09.036 10.1111/bph.13812 10.5152/npa.2016.12553 10.1001/archpedi.161.7.641 10.1521/suli.2009.39.5.518 10.1210/jcem-52-5-942 10.1007/s10862-008-9107-z 10.1016/j.psychres.2010.09.009 10.1016/j.jadohealth.2012.09.010 10.1038/nrn1431 10.3109/07420528.2012.699122 10.1046/j.1468-2982.1990.1005251.x 10.1016/j.euroneuro.2020.07.010 10.1176/appi.ajp.2009.09050744 10.1176/ajp.156.6.842 10.1136/bmj.288.6435.1950 10.1037/h0080336 10.5505/kpd.2018.77598
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Snippet	Non-suicidal self-injury (NSSI) is one of the most common mental health problems and growing public-health issues, coupled with a significant population-level... ObjectiveNon-suicidal self-injury (NSSI) is one of the most common mental health problems and growing public-health issues, coupled with a significant...
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SubjectTerms	Adolescent Adolescents Analgesics, Opioid beta-endorphin brief symptom inventory Child Developing countries Emotional Regulation Emotions Endogenous Health problems Humans Injuries inventory of statements about self-injury LDCs Measurement Measures Mental depression Mental disorders Mental health Narcotics Neuropeptides non-suicidal self-injury Opioids Plasma Plasma levels Property Psychometrics Public health Quantitative psychology Research subjects Self destructive behavior Self evaluation Self injury Self-Injurious Behavior - psychology Sociodemographics Suicidal behavior Suicide Teenagers
Title	Assessment of Plasma-Endogenous Opioid Neuropeptide Levels and Psychometric Properties of Non-Suicidal Self-Injury in Adolescents
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