High‐dose glucocorticoids for the treatment of ipilimumab‐induced hypophysitis is associated with reduced survival in patients with melanoma

BACKGROUND It remains unclear whether high doses of glucocorticoids have a negative impact on the efficacy of checkpoint inhibitors. To control for the potential association between immune‐related adverse events (irAEs) and improved survival, this study examined a unique cohort of patients who had t...

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Bibliographic Details
Published in:	Cancer Vol. 124; no. 18; pp. 3706 - 3714
Main Authors:	Faje, Alexander T., Lawrence, Donald, Flaherty, Keith, Freedman, Christine, Fadden, Riley, Rubin, Krista, Cohen, Justine, Sullivan, Ryan J.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 15.09.2018
Subjects:	checkpoint inhibitors Electronic health records Electronic medical records Glucocorticoids Health care hypophysitis Immune checkpoint Immunotherapy Inhibitors ipilimumab Melanoma Monoclonal antibodies Oncology Patients Survival melanoma hypophysitis glucocorticoids checkpoint inhibitors ipilimumab
ISSN:	0008-543X, 1097-0142, 1097-0142
Online Access:	Get full text
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