Validation of a novel molecular diagnostic panel for pediatric musculoskeletal infections: Integration of the Cepheid Xpert MRSA/SA SSTI and laboratory-developed real-time PCR assays for clindamycin resistance genes and Kingella kingae detection

Pathogen detection in pediatric patients with musculoskeletal infections relies on conventional bacterial culture, which is slow and can delay antimicrobial optimization. The ability to rapidly identify causative agents and antimicrobial resistance genes in these infections may improve clinical care...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of microbiological methods Vol. 156; pp. 60 - 67
Main Authors:	Searns, Justin B., Robinson, Christine C., Wei, Qi, Yuan, Ji, Hamilton, Stacey, Pretty, Kristin, Donaldson, Nathan, Parker, Sarah K., Dominguez, Samuel R.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.01.2019
Subjects:	Anti-Bacterial Agents - therapeutic use antibiotic resistance antibiotic resistance genes Bacterial Proteins - genetics Child children clindamycin Clindamycin - therapeutic use Colorado Diagnostics Drug Resistance, Bacterial Female hospitals Humans Infection Kingella kingae Kingella kingae - genetics Kingella kingae - isolation & purification Male methicillin-resistant Staphylococcus aureus Methyltransferases - genetics microbial detection musculoskeletal system Neisseriaceae Infections - diagnosis Osteoarthritis - microbiology Osteomyelitis Osteomyelitis - microbiology patients Pediatric phenotype quantitative polymerase chain reaction Septic arthritis Colorado Osteomyelitis Infection Diagnostics NPV Septic arthritis PPV MDP qPCR Pediatric CHCO
ISSN:	0167-7012, 1872-8359, 1872-8359
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!