Intensive exercise ameliorates motor and cognitive symptoms in experimental Parkinson’s disease restoring striatal synaptic plasticity

Intensive physical activity improves motor functions in patients with Parkinson’s disease (PD) at early stages. However, the mechanisms underlying the beneficial effects of exercise on PD-associated neuronal alterations have not been fully clarified yet. Here, we tested the hypothesis that an intens...

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Veröffentlicht in:	Science advances Jg. 9; H. 28; S. eadh1403
Hauptverfasser:	Marino, Gioia, Campanelli, Federica, Natale, Giuseppina, De Carluccio, Maria, Servillo, Federica, Ferrari, Elena, Gardoni, Fabrizio, Caristo, Maria Emiliana, Picconi, Barbara, Cardinale, Antonella, Loffredo, Vittorio, Crupi, Francesco, De Leonibus, Elvira, Viscomi, Maria Teresa, Ghiglieri, Veronica, Calabresi, Paolo
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States American Association for the Advancement of Science 14.07.2023
Schlagworte:	Animals Cognition Corpus Striatum Diseases and Disorders Long-Term Potentiation - physiology Neuronal Plasticity - physiology Neuroscience Parkinson Disease - therapy Rats SciAdv r-articles
ISSN:	2375-2548, 2375-2548
Online-Zugang:	Volltext
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