Clinical and microbiological characterization of localized aggressive periodontitis: a cohort study

Background Localized aggressive periodontitis (LAgP) is an infectious periodontal disease which generally affects young people. Recent data suggest the involvement of different bacterial species in different populations. The causative bacterial species in Israel has never been identified despite a h...

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Vydáno v:Australian dental journal Ročník 59; číslo 2; s. 165 - 171
Hlavní autoři: Oettinger‐Barak, O, Sela, MN, Sprecher, H, Machtei, EE
Médium: Journal Article
Jazyk:angličtina
Vydáno: Australia 01.06.2014
Témata:
Adolescent
Adult
Aggregatibacter actinomycetemcomitans
Aggregatibacter actinomycetemcomitans - isolation & purification
Aggressive Periodontitis - microbiology
Aggressive Periodontitis - pathology
Chi-Square Distribution
Child
Chronic Periodontitis
clinical manifestation
Cohort Studies
Dental Plaque - microbiology
Female
Fusobacterium - isolation & purification
Fusobacterium nucleatum - isolation & purification
Humans
Israel
localized aggressive periodontitis
Male
Middle Aged
periodontal microbiology
Periodontal Pocket - microbiology
Polymerase Chain Reaction
population studies
Porphyromonas gingivalis - isolation & purification
Prevotella intermedia - isolation & purification
Statistics, Nonparametric
Young Adult
Israel
Aggregatibacter actinomycetemcomitans
periodontal microbiology
localized aggressive periodontitis
population studies
clinical manifestation
ISSN:0045-0421, 1834-7819, 1834-7819
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Shrnutí:Background Localized aggressive periodontitis (LAgP) is an infectious periodontal disease which generally affects young people. Recent data suggest the involvement of different bacterial species in different populations. The causative bacterial species in Israel has never been identified despite a high prevalence of LAgP in this population. The objectives of this study were to characterize the bacterial microbiota of periodontal pockets within an Israeli LAgP population who were also clinically assessed. Methods Twenty‐one LAgP patients (test) and 12 chronic periodontitis patients (control) were examined. Bacterial samples were collected from periodontal pockets and analysed by both culture and polymerase chain reaction techniques. Mann–Whitney U test and chi‐square test were used to compare results between the groups. Results Higher levels of Parvimonas micra (>106), Aggregatibacter actinomycetemcomitans (>105), Fusobacterium nucleatum/F. periodonticum (>106), and Tannerella forsythia (levels of 105 to 106 bacteria) were detected in the LAgP group compared to the control (p < 0.05), while levels of Porphyromonas gingivalis and Prevotella intermedia were higher in the CP group. Conclusions The characteristic periodontal bacterial flora of LAgP patients in Israel is mainly comprised of P. micra, A. actinomycetemcomitans, F. nucleatum/F. periodonticum and T. forsythia. Similar population based studies of each population will improve the quality of treatment of LAgP when individual sampling is not possible.
Bibliografie:ObjectType-Article-1
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ISSN:0045-0421
1834-7819
1834-7819
DOI:10.1111/adj.12165