First detection and analysis of a fish circovirus
Circoviruses are present worldwide in birds and pigs but their occurrence in fish has not yet been reported. Recently, increased mortality was observed in barbel fry (Barbus barbus) in Hungary. This paper reports the detection of previously unknown circular viral DNA genomes in barbels by the use of...
Uložené v:
| Vydané v: | Journal of general virology Ročník 92; číslo Pt 8; s. 1817 |
|---|---|
| Hlavní autori: | , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
England
01.08.2011
|
| Predmet: | |
| ISSN: | 1465-2099, 1465-2099 |
| On-line prístup: | Zistit podrobnosti o prístupe |
| Tagy: |
Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
|
| Abstract | Circoviruses are present worldwide in birds and pigs but their occurrence in fish has not yet been reported. Recently, increased mortality was observed in barbel fry (Barbus barbus) in Hungary. This paper reports the detection of previously unknown circular viral DNA genomes in barbels by the use of a circovirus-specific wide-range nested PCR. The analysis of two complete genomes (Barbel circovirus, BaCV1 and BaCV2) indicated that they belonged into a new genetic group within the family Circoviridae, distinct from known circoviruses and circovirus-like genomes. Their genome size was 1957 bases and contained two major ORFs similar to the capsid and replication-associated protein genes of circoviruses. A connection between the presence of the virus and clinical manifestations of the infection could not be proved. |
|---|---|
| AbstractList | Circoviruses are present worldwide in birds and pigs but their occurrence in fish has not yet been reported. Recently, increased mortality was observed in barbel fry (Barbus barbus) in Hungary. This paper reports the detection of previously unknown circular viral DNA genomes in barbels by the use of a circovirus-specific wide-range nested PCR. The analysis of two complete genomes (Barbel circovirus, BaCV1 and BaCV2) indicated that they belonged into a new genetic group within the family Circoviridae, distinct from known circoviruses and circovirus-like genomes. Their genome size was 1957 bases and contained two major ORFs similar to the capsid and replication-associated protein genes of circoviruses. A connection between the presence of the virus and clinical manifestations of the infection could not be proved.Circoviruses are present worldwide in birds and pigs but their occurrence in fish has not yet been reported. Recently, increased mortality was observed in barbel fry (Barbus barbus) in Hungary. This paper reports the detection of previously unknown circular viral DNA genomes in barbels by the use of a circovirus-specific wide-range nested PCR. The analysis of two complete genomes (Barbel circovirus, BaCV1 and BaCV2) indicated that they belonged into a new genetic group within the family Circoviridae, distinct from known circoviruses and circovirus-like genomes. Their genome size was 1957 bases and contained two major ORFs similar to the capsid and replication-associated protein genes of circoviruses. A connection between the presence of the virus and clinical manifestations of the infection could not be proved. Circoviruses are present worldwide in birds and pigs but their occurrence in fish has not yet been reported. Recently, increased mortality was observed in barbel fry (Barbus barbus) in Hungary. This paper reports the detection of previously unknown circular viral DNA genomes in barbels by the use of a circovirus-specific wide-range nested PCR. The analysis of two complete genomes (Barbel circovirus, BaCV1 and BaCV2) indicated that they belonged into a new genetic group within the family Circoviridae, distinct from known circoviruses and circovirus-like genomes. Their genome size was 1957 bases and contained two major ORFs similar to the capsid and replication-associated protein genes of circoviruses. A connection between the presence of the virus and clinical manifestations of the infection could not be proved. |
| Author | Tuboly, Tamás Székely, Csaba Cságola, Attila Lőrincz, Márta Farkas, Szilvia L |
| Author_xml | – sequence: 1 givenname: Márta surname: Lőrincz fullname: Lőrincz, Márta organization: Szent István University, Faculty of Veterinary Science, Department of Microbiology and Infectious Diseases, Hungária krt. 23-25, H-1143 Budapest, Hungary – sequence: 2 givenname: Attila surname: Cságola fullname: Cságola, Attila organization: Szent István University, Faculty of Veterinary Science, Department of Microbiology and Infectious Diseases, Hungária krt. 23-25, H-1143 Budapest, Hungary – sequence: 3 givenname: Szilvia L surname: Farkas fullname: Farkas, Szilvia L organization: Veterinary Medical Research Institute, Hungarian Academy of Sciences, Hungária krt. 21, H-1143 Budapest, Hungary – sequence: 4 givenname: Csaba surname: Székely fullname: Székely, Csaba organization: Veterinary Medical Research Institute, Hungarian Academy of Sciences, Hungária krt. 21, H-1143 Budapest, Hungary – sequence: 5 givenname: Tamás surname: Tuboly fullname: Tuboly, Tamás organization: Szent István University, Faculty of Veterinary Science, Department of Microbiology and Infectious Diseases, Hungária krt. 23-25, H-1143 Budapest, Hungary |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/21525210$$D View this record in MEDLINE/PubMed |
| BookMark | eNpNj81LxDAQxYOsuB969Si5eWqdSZO2OcriqrDgRc8lTVKMtM2atML-9wZ2BQ_DPHi_eY9Zk8XoR0vILUKOIOXDjws55FBgwXkGF2SFvBQZS9bin16SdYxfAMi5qK7IkqFggiGsCO5ciBM1drJ6cn6kajRpVH-MLlLfUUU7Fz-pdkH7VDbHa3LZqT7am_PekI_d0_v2Jdu_Pb9uH_eZLiRMWSsKU7esahUTojQgEbniSRjBpNSi0BYqpVnLal0iWq27xJSytgiQjtiG3J9yD8F_zzZOzeCitn2vRuvn2NRVxUEKViby7kzO7WBNcwhuUOHY_H3JfgHcL1RI |
| CitedBy_id | crossref_primary_10_1128_jvi_01737_24 crossref_primary_10_1016_j_virusres_2019_197826 crossref_primary_10_1099_jgv_0_000529 crossref_primary_10_1111_xen_12842 crossref_primary_10_1016_j_virusres_2024_199428 crossref_primary_10_1128_JVI_02222_18 crossref_primary_10_1016_j_virusres_2018_03_014 crossref_primary_10_3390_v15102025 crossref_primary_10_1186_s40168_022_01431_8 crossref_primary_10_1016_j_meegid_2021_105070 crossref_primary_10_1016_j_aquaculture_2024_741660 crossref_primary_10_3390_v13061042 crossref_primary_10_1099_vir_0_037838_0 crossref_primary_10_1016_j_antiviral_2012_06_003 crossref_primary_10_1007_s00705_021_05202_y crossref_primary_10_3389_fmicb_2024_1298106 crossref_primary_10_3390_v13091700 crossref_primary_10_3390_v13091865 crossref_primary_10_3390_pathogens13020150 crossref_primary_10_1007_s13337_013_0186_4 crossref_primary_10_1099_vir_0_045948_0 crossref_primary_10_3390_v13050944 crossref_primary_10_1186_1471_2148_11_276 crossref_primary_10_3389_fmicb_2017_00406 crossref_primary_10_1128_spectrum_00780_22 crossref_primary_10_3390_v11121092 crossref_primary_10_1007_s00705_024_06107_2 crossref_primary_10_1186_s13567_019_0653_z crossref_primary_10_1016_j_psj_2022_101767 crossref_primary_10_1016_j_virusres_2013_09_018 crossref_primary_10_1292_jvms_16_0642 crossref_primary_10_1016_j_virusres_2018_07_015 crossref_primary_10_1186_s13567_020_00876_9 crossref_primary_10_1007_s11262_013_1003_2 crossref_primary_10_1016_j_aquaculture_2025_743228 crossref_primary_10_1016_j_virusres_2011_11_021 crossref_primary_10_3389_fmars_2022_945289 crossref_primary_10_3390_life12030368 crossref_primary_10_1007_s00705_012_1391_y crossref_primary_10_1007_s00705_017_3247_y crossref_primary_10_3389_fmicb_2022_1011342 crossref_primary_10_1007_s11262_013_0928_9 crossref_primary_10_1111_nyas_12675 crossref_primary_10_1186_s12985_016_0642_z crossref_primary_10_3389_fvets_2021_736366 crossref_primary_10_1007_s00705_012_1291_1 crossref_primary_10_1016_j_bbrc_2013_07_122 crossref_primary_10_3390_v16020228 crossref_primary_10_1016_j_meegid_2016_02_009 |
| ContentType | Journal Article |
| DBID | CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1099/vir.0.031344-0 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Biology |
| EISSN | 1465-2099 |
| ExternalDocumentID | 21525210 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | --- -~X .55 .GJ 186 18M 2WC 39C 3O- 4.4 53G 5GY 5RE AAJMC ABDNZ ACBTR ACGFO ACPEE ACYGS ADBBV ADCDP ADCOW AEILP AENEX AFFNX AGCDD AI. AJKYU ALMA_UNASSIGNED_HOLDINGS BAWUL C1A CGR CJ0 CS3 CUY CVF DIK DU5 E3Z EBS ECM EIF EJD F5P FRP GX1 H13 IH2 K-O L7B NPM OHT OK1 P2P RGM TR2 VH1 W8F WH7 WHG WOQ X7M Y6R YKV YSK ZGI ~KM 7X8 |
| ID | FETCH-LOGICAL-c390t-b53d8b27ba2556d09114a46d0d5299c53ce07ac2b28c611eccf091698e100ba22 |
| IEDL.DBID | 7X8 |
| ISICitedReferencesCount | 68 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000293488800010&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1465-2099 |
| IngestDate | Fri Jul 11 15:09:27 EDT 2025 Thu Apr 03 07:01:38 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | Pt 8 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c390t-b53d8b27ba2556d09114a46d0d5299c53ce07ac2b28c611eccf091698e100ba22 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| PMID | 21525210 |
| PQID | 877409526 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_877409526 pubmed_primary_21525210 |
| PublicationCentury | 2000 |
| PublicationDate | 2011-08-01 |
| PublicationDateYYYYMMDD | 2011-08-01 |
| PublicationDate_xml | – month: 08 year: 2011 text: 2011-08-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England |
| PublicationTitle | Journal of general virology |
| PublicationTitleAlternate | J Gen Virol |
| PublicationYear | 2011 |
| SSID | ssj0014457 |
| Score | 2.3046818 |
| Snippet | Circoviruses are present worldwide in birds and pigs but their occurrence in fish has not yet been reported. Recently, increased mortality was observed in... |
| SourceID | proquest pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | 1817 |
| SubjectTerms | Animals Circoviridae - classification Circoviridae - genetics Circoviridae - isolation & purification Circoviridae Infections - veterinary Circoviridae Infections - virology Cyprinidae - virology Fish Diseases - virology Genome, Viral Molecular Sequence Data Phylogeny |
| Title | First detection and analysis of a fish circovirus |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/21525210 https://www.proquest.com/docview/877409526 |
| Volume | 92 |
| WOSCitedRecordID | wos000293488800010&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV07T8MwED4BBYmF96O85IHVxXGchyeEEBUDVB1A6hb5FZElKU1biX_POUnLhBgYEmWII-t8vvvOd_kO4DZPwlzoSFLFrKJCWkulEJJaprXjhqM5bHhmX5LRKJ1M5Lirzam7ssqVTWwMta2MPyO_SxGnIBzg8f30k_qmUT652nXQ2IReiEjGK3Uy-UkiCNEQfaItiKj_Q3TN2SjvlsVswAaet1AIyn5Hl42XGe7_c34HsNfBS_LQ6sMhbLjyCHbahpNfxxAMC0R7xLp5U4FVElVavFpeElLlRJG8qD-IKWamwtkv6hN4Hz69PT7TrmkCNaFkc6qj0KaaJ1p5cjGLcCAQSuCDjdDzmCg0jiXKcM1TEwcBrmCO78QydQFjOIifwlZZle4cSIzbM9UykQq_gI5cKYyNMFxLQoypXaD7QFaiyFApfaZBla5a1NlaGH04a8WZTVvyjMz30UXIwC7-HnwJu6sTXBZcQS_HDemuYdss50U9u2kWG--j8es3M5iyAg |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=First+detection+and+analysis+of+a+fish+circovirus&rft.jtitle=Journal+of+general+virology&rft.au=L%C5%91rincz%2C+M%C3%A1rta&rft.au=Cs%C3%A1gola%2C+Attila&rft.au=Farkas%2C+Szilvia+L&rft.au=Sz%C3%A9kely%2C+Csaba&rft.date=2011-08-01&rft.issn=1465-2099&rft.eissn=1465-2099&rft.volume=92&rft.issue=Pt+8&rft.spage=1817&rft_id=info:doi/10.1099%2Fvir.0.031344-0&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1465-2099&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1465-2099&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1465-2099&client=summon |