A modular, reusable biocatalytic flow system for UDP-GlcNAc production

We report here the continuous flow synthesis of a high-value sugar nucleotide. Immobilisation of enzymes onto solid carriers permitted transfer of the biocatalysts into packed bed reactors to realise a continuous biocatalytic platform for the synthesis of uridine diphosphate N -acetylglucosamine (UD...

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Bibliographic Details
Published in:	Reaction chemistry & engineering Vol. 1; no. 6; pp. 1221 - 1226
Main Authors:	Roberts, Tom L, Dolan, Jonathan P, Miller, Gavin J, Lima, Marcelo A. D, Cosgrove, Sebastian C
Format:	Journal Article
Language:	English
Published:	England Royal Society of Chemistry 28.05.2025 The Royal Society of Chemistry
Subjects:	Chemistry Continuous flow Glycan Glycoproteins Modular systems Nucleotides Oligosaccharides Packed beds Synthesis Thermal stability
ISSN:	2058-9883, 2058-9883
Online Access:	Get full text
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