Treatment with 2,4-Dihydroxybenzoic Acid Prevents FSGS Progression and Renal Fibrosis in Podocyte-Specific Coq6 Knockout Mice

Although studies have identified >55 genes as causing steroid-resistant nephrotic syndrome (SRNS) and localized its pathogenesis to glomerular podocytes, the disease mechanisms of SRNS remain largely enigmatic. We recently reported that individuals with mutations in COQ6, a coenzyme Q (also calle...

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Veröffentlicht in:	Journal of the American Society of Nephrology Jg. 30; H. 3; S. 393
Hauptverfasser:	Widmeier, Eugen, Airik, Merlin, Hugo, Hannah, Schapiro, David, Wedel, Johannes, Ghosh, Chandra C, Nakayama, Makiko, Schneider, Ronen, Awad, Agape M, Nag, Anish, Cho, Jang, Schueler, Markus, Clarke, Catherine F, Airik, Rannar, Hildebrandt, Friedhelm
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.03.2019
Schlagworte:	focal segmental glomerulosclerosis nephrotic syndrome podocyte
ISSN:	1533-3450, 1533-3450
Online-Zugang:	Weitere Angaben
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