Sotagliflozin in Patients with Diabetes and Chronic Kidney Disease

In a trial involving 10,584 patients with diabetes and chronic kidney disease, sotagliflozin resulted in fewer total deaths from cardiovascular causes, hospitalizations for heart failure, and urgent visits for heart failure than placebo. Diarrhea, mycotic infections, and diabetic ketoacidosis occurr...

Full description

Saved in:

Bibliographic Details
Published in:	The New England journal of medicine Vol. 384; no. 2; pp. 129 - 139
Main Authors:	Bhatt, Deepak L, Szarek, Michael, Pitt, Bertram, Cannon, Christopher P, Leiter, Lawrence A, McGuire, Darren K, Lewis, Julia B, Riddle, Matthew C, Inzucchi, Silvio E, Kosiborod, Mikhail N, Cherney, David Z.I, Dwyer, Jamie P, Scirica, Benjamin M, Bailey, Clifford J, Díaz, Rafael, Ray, Kausik K, Udell, Jacob A, Lopes, Renato D, Lapuerta, Pablo, Steg, P. Gabriel
Format:	Journal Article
Language:	English
Published:	United States Massachusetts Medical Society 14.01.2021
Subjects:	Adverse events Aged Cardiovascular diseases Cardiovascular Diseases - epidemiology Cardiovascular Diseases - mortality Cerebral infarction Confidence intervals Congestive heart failure Corporate sponsorship Creatinine Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy Diabetic ketoacidosis Diabetic Ketoacidosis - chemically induced Diarrhea Diarrhea - chemically induced Double-Blind Method Female Glomerular filtration rate Glucose Glycosides - adverse effects Glycosides - therapeutic use Heart attacks Heart failure Hemoglobin Hospitalization Hospitalization - statistics & numerical data Humans Ketoacidosis Kidney diseases Male Middle Aged Mycoses - etiology Myocardial infarction Patients Placebos Renal Insufficiency, Chronic - complications Renal Insufficiency, Chronic - drug therapy Risk factors Sodium-glucose cotransporter Sodium-Glucose Transporter 1 - antagonists & inhibitors Sodium-Glucose Transporter 2 Inhibitors - adverse effects Sodium-Glucose Transporter 2 Inhibitors - therapeutic use Statistical analysis Europe
ISSN:	0028-4793, 1533-4406, 1533-4406
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!