Autophagy in kidney disease and aging: lessons from rodent models

Autophagy is a highly regulated lysosomal protein degradation pathway that removes protein aggregates and damaged or excess organelles to maintain intracellular homeostasis and cell integrity. Dysregulation of autophagy is involved in the pathogenesis of a variety of metabolic and age-related diseas...

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Bibliographic Details

Published in:	Kidney international Vol. 90; no. 5; pp. 950 - 964
Main Authors:	Lenoir, Olivia, Tharaux, Pierre-Louis, Huber, Tobias B
Format:	Journal Article
Language:	English
Published:	United States 01.11.2016
Subjects:	Aging - physiology Animals Autophagy Kidney Diseases - physiopathology endothelium kidney autophagy polycystic kidney disease kidney transplantation podocyte mTOR acute kidney injury aging glomerulus
ISSN:	1523-1755
Online Access:	Get more information
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